Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID77257	Vorinostat	GSE92742	NKDBA	Human	24h	10uM	EID0449

Response Information :

Types	Number	Response transcription factors
Up-regulation	133	NR1H2; BCL3; CREM; SETDB1; ADRB2; ZNF354A; PHF1; NHLH2; HMBOX1; PBXIP1; CDYL; ZNF446; HDAC1; NR4A3; STAT2; JUNB; ZNF331; ERBB4; HEY1; DACH1; LZTR1; ZNF43; HABP4; PFDN5; TCF7L2; TDRD3; PEG3; ZNF44; CAMTA1; POU4F1; CCNE1; HHEX; JUP; ING4; ARNTL; PRDM2; ZNF571; FLI1; SATB2; EVX1; SOX4; ZSCAN5A; ZNF117; RFXANK; TULP4; CREB5; ZNF692; RUVBL1; KLF7; HMGXB3; SUPT4H1; NR5A2; HMG20B; ZNF394; SREBF1; EPAS1; MEF2C; PPARG; TRPS1; MED15; NR3C2; SOHLH2; FOXO4; CBX4; NR4A2; ZNF45; ZNF224; AIP; RHOA; ZNF257; RORA; ZNF573; MZF1; STAT1; TBPL1; NKX2-1; SPIB; ZNF468; STAT4; ZNF226; ZNF85; GTF2F1; SP110; DLX2; HIC2; MXI1; TOB1; RBBP4; BACH2; RELB; IRF4; PHF20; BANP; RREB1; IL16; TCEA2; PARP1; MNAT1; FUBP1; LITAF; EYA1; MAF; ZNF544; HEY2; LOXL2; DLX5; ZNF266; CEBPD; SOX11; SIRT7; VPS72; CHD7; HOXA5; ID3; ATF3; BCL11A; PROX1; INSM1; HIVEP1; ZNF91; PAX5; SMARCA1; GATA3; TRIM16; E2F3; SCAND1; IRF7; DRAP1; KLF11; ID1; BASP1; ID4; HOXD1
Down-regulation	225	CCNA2; SUV39H1; FHL2; ERBB2; ATF1; PTRF; FOSL1; HMGB2; ZFP36L1; CHD9; ZBED1; HOXA10; BRCA1; NUP62; PCBD1; TGFB1I1; CBX5; HMGB1; ETS2; PHF2; IFI16; ZBTB16; BAZ1B; HOXB2; FOXM1; EWSR1; YEATS2; BACH1; HNRNPD; SMARCC1; TFAM; SMARCC2; ADNP; UBE3A; ZNF148; ATF4; GABPB1; PTTG1; ELF5; HMG20A; DEK; REPIN1; NR2F2; PHF8; MYC; TRIM22; TFEB; BMI1; TEAD4; TRIP6; HMGXB4; CENPB; NCOR1; SP140L; SUZ12; RNF6; NFKB1; TCERG1; RBM14; NPAS2; NFYB; ZMIZ1; ZBTB38; MAFF; SCMH1; WHSC1; COPS2; SMARCD2; CTBP1; USP22; TCF12; SRF; CNOT1; UBP1; EHF; BCLAF1; CBX3; PSIP1; PATZ1; TCEA1; PRMT2; NCOR2; CENPF; YBX3; HDAC2; HDAC6; CNBP; MDM2; CHD3; STAT5A; SAP30; RARA; CNOT2; UBE2I; ZNF22; MTA1; NFIC; NFE2L1; ARL2BP; SF1; HMGA1; ARNTL2; STAT6; NKX3-1; SFMBT1; ZNF654; SMAD4; TRAF6; SP3; DNAJC2; BAZ1A; MBD3; TSC22D3; SMARCE1; RAD21; TULP3; NCOA2; WDHD1; NCOA4; HOXB6; KLF4; TLE2; OVOL2; HOXB13; PDLIM1; ZNF146; HMGA2; TERF2; CTCF; ETV6; ZBED4; MAGED1; CARM1; RNF111; MED21; CREB3L1; MECP2; PMF1; BTAF1; THAP11; TFE3; RBFOX2; CCDC59; ING2; ZKSCAN1; BTG1; TAF9; ZNF189; YWHAB; SMARCA2; SNW1; HLF; RBPMS; MED24; ZEB2; CBFB; FOXN3; BAZ2B; ZSCAN18; AES; SMAD1; HOXB7; PPRC1; DNAJC1; MTF2; PMS1; TRRAP; HMGN3; CDK8; SP100; EGR2; EZH2; MEIS2; GTF2IRD1; ZNF282; SIAH2; NCOA6; NAB1; AFF1; MED1; MSX1; TCF21; ZMYM2; NEUROD1; ZEB1; HOXC6; ZNF532; TBL1X; HOXC10; PBX2; TP53; TOPORS; MLXIP; ZMYND8; TFAP2C; DMTF1; TRIM32; KLF10; ECD; SMAD7; FLNA; MBD2; RAN; CRK; YBX1; ELF1; ZNF12; MAFB; GATA6; ZBTB20; SOX9; IRF8; KLF6; NRIP1; ETV5; EGR3; FOXD1; WWTR1; ZFPM2; DNMT1; ZNF131; SNAI2; KDM5D; MEIS1; POU2AF1