Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID77214	Cgs-15943	GSE92742	NKDBA	Human	24h	5uM	EID0448

Response Information :

Types	Number	Response transcription factors
Up-regulation	306	ETV1; ZNF131; ZNF586; PARP1; EPAS1; NFE2L2; FOXC1; SOX2; ADRB2; TBX2; PAX5; NFATC1; MAFB; ZNF165; FOS; RELB; AFF4; FOXI1; TRRAP; NFX1; MYCN; NR4A2; HDAC4; MAML1; KDM5B; ELK4; LYL1; GLI2; HTATIP2; LITAF; ZBTB17; CRTC1; GATA4; KDM5A; LMX1B; FOXO1; SAFB2; AEBP1; NKX2-5; PAWR; NFYA; CBX6; GFI1; ECD; HLX; GABPA; NFKBIB; EHMT1; CTNNB1; MEF2A; SAFB; CBL; MDM2; ZNF253; ZBED1; NR2F1; SIN3B; LHX5; POU2F2; GATA2; KLF15; BTG1; MED21; TOPORS; TP63; ARID3A; TLX3; SPIB; SMAD5; PIAS1; NFYB; HR; TCF20; ZNF281; IKZF5; FOSB; CBFA2T3; CRK; KMT2A; XBP1; SNAI1; ZNF688; KAT6B; RFX1; ZBTB25; TSC22D2; ZNF528; TAF1A; NHLH1; ZEB2; HOXA5; MLXIP; SIRT2; CBX7; SRY; RFX7; CUX1; ZNF614; ZNF671; GABPB1; NR4A1; PURA; JAK2; FOXH1; CHD1; ZNF268; ZHX2; YAF2; GTF2I; SERTAD2; SKI; ASH1L; BRWD1; DLX5; ZNF189; MBD1; HOXA1; ZNF557; AATF; SOX4; ETS1; PIR; ZNF222; HOXC5; SKIL; CIITA; ZBTB39; PPARG; EP300; ZNF335; RAX; IL16; MTF1; ZNF556; MXD4; PRDM8; RXRA; DYRK1B; CREB3; ING1; CNOT6; FOXC2; ZBTB40; ADNP; GCFC2; RNF111; RNF141; PEG3; ETS2; ZNF510; CREBZF; ZNF10; TAF7L; ELF1; POLR2A; NCOA1; TFEB; MDM4; PIAS2; PRRX1; MKL1; MYT1L; TAF7; CCNE1; MECP2; TCF3; TRIM16; TAF5; ATF7IP; TCF7L2; STAT2; RARG; EGR1; TAF5L; TAF1; MTA1; AFF1; TAF4; HSF4; HHEX; ZBTB48; NR5A2; CDK9; BTAF1; ZNF195; MZF1; MED25; IRX5; ZBTB18; NRBF2; LPIN2; ERCC2; IRX4; HIPK2; BLZF1; TLE2; CAMTA1; UIMC1; TAF12; PHF8; PMS1; ID3; KLF3; CIZ1; SCAND1; FOXJ1; TRIM29; ARID4A; RBM14; ING3; MXD1; TSG101; KLF9; ZNF430; MAX; BAZ2B; REPIN1; NR2F2; BRD8; NR0B1; NR0B2; ZBTB7A; ZNF14; IRF4; NR1H2; BBX; HBP1; PKNOX1; MNDA; HSF2; TGIF1; MYRF; MED7; OSR2; HMBOX1; SOX13; ZNF267; SUPT3H; SPEN; ASCL1; HES1; ZNF552; CSDC2; JUNB; ZNF232; ZNF721; SNAI2; RBM39; EGR3; TOB1; MAFG; NCOR2; HDAC6; WDR77; POU2AF1; VEZF1; ERG; HIPK3; THAP11; SMAD6; PPP1R13L; HIC2; AGO2; ZNF227; BACH2; ZNF124; DLX2; INSR; DDIT3; TGFB1; CREG1; MSX1; ZNF45; PCGF3; DMTF1; HOXC6; FUBP1; ZFP36L2; TULP4; PNRC1; ZNF331; TCF21; RERE; GMNN; CEBPG; CTR9; CREM; FOXD1; HOXA10; HOXA11; TDP2; SMAD7; ZMYM2; ID2; NR1H3; GATA6; MXI1; JUP; KLF2; HMGN3; ST18; RFX5; VDR; RUNX3; PDLIM1; TFAP2C
Down-regulation	295	BIRC2; ZFP36L1; GTF2IRD1; TRIB3; LOXL2; FHL2; ZNF133; DACH1; FOXG1; USP22; PCGF2; CERS6; MYC; DRAP1; HDAC2; ATF5; BTF3; PBX2; PA2G4; MAZ; CBX3; SMARCC1; PCBD1; ZNF302; CCNC; HMGXB4; MYCL; AHR; ZFHX4; RHOA; ILF2; SP100; INSM1; SETDB1; HMG20B; ZNF587; HDGF; ZNF248; DEK; SMARCD2; FOSL1; KLF1; PMF1; SMARCE1; PBX1; TADA3; SP3; MTDH; TAL1; RXRG; BRD7; TULP3; ZNF22; ZNF74; MED24; ZNF83; NFKB2; SMARCA4; ZNF239; TEAD3; TSC22D3; ELK3; CALR; RLF; TLE4; ESR1; MEOX2; CCNA2; ADNP2; CAPN15; RNF2; SOX11; ZNF512B; CBFB; HOXD13; FOXJ3; CEBPZ; ZZZ3; SETD2; ZNF787; ZNF135; JUN; THRA; YBX1; PUF60; NUP62; RXRB; STAT6; OVOL2; ZNF415; ENY2; ZNF345; ZSCAN12; SUB1; IFI16; ZNF155; AR; HMGB3; TFCP2; ZNF410; FOXJ2; SMARCA1; SP140L; RORA; JUND; HOXB5; ZNF606; SALL2; CHD4; NONO; HMGB2; ZFPM2; RBBP4; SUV39H1; BHLHE40; RNF138; ATF3; DR1; SLC2A4RG; ZNF148; E2F3; SOX12; MED14; PSIP1; MYCBP; ZNF334; ZNF223; CLOCK; PBRM1; CENPF; ZNF76; GFI1B; MSL3; FOXF1; RELA; SP110; CRYM; CBX5; TOX; PRKDC; EMX2; TTF1; SSBP2; HOXB6; PITX1; DEAF1; CSDE1; KLF10; E4F1; YEATS4; ZNF250; ZNF146; ZSCAN16; WHSC1; MAGED1; TBL1XR1; FOXM1; ZNF112; ABL1; PRDM4; NRIP1; CDYL; NFYC; SIX6; ZFP69B; CCDC59; SRF; KLF7; RFXANK; VPS72; LDB1; TGFB1I1; L3MBTL1; MED4; ATF1; HOXB13; HIRA; ERBB2; MYBL2; SAP18; HIVEP1; ZNF432; ZNF177; HEY1; ZNF32; EN1; PQBP1; BHLHE41; NFKBIA; ZSCAN18; CARM1; HMGB1; TFAM; KLF6; NR1I2; ZNF12; SSRP1; HMGA1; ZNF274; TWIST1; RING1; NFE2; STAT5A; SUPT4H1; HDAC1; SCMH1; RBBP8; ZNF3; ZNF136; SMAD2; ELF4; TAF11; SAP30; RAN; POLR3C; BMI1; STAT1; BNC1; USP21; ATF6; NEDD8; RAD21; ZBTB20; HSBP1; TEAD4; BNC2; NR1H4; TCEA1; ZBTB11; HOXB2; SATB2; ZNF44; GTF3A; MEIS1; ATN1; ZMIZ2; MKL2; TOX3; ZNF562; SMARCD3; SPDEF; CALCOCO1; CENPB; ARL2BP; TRIM28; BCLAF1; ACTL6A; LEF1; CCNH; PEX14; WT1; MED1; TRIP6; NKX2-1; CRY1; NANOG; NKX2-2; KLF5; PAX8; ZNF580; ZNF623; CUX2; ZEB1; ZNF544; CREB3L1; RYBP; TCF12; EZH2; BATF3; HOXD1; NFIB; ID4; JARID2; WWTR1; ZNF91; SALL1; PLAGL1; DNAJC2; KAT2B; MTF2; RBPJ; ID1; ETV5; SIX1; MECOM; HOXB7; SATB1; ZBTB38; CITED2; FLNA; MYBL1; ARID5B; TBX3; TRIM22; STAT5B