Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID77201	Pevonedistat	GSE92742	NKDBA	Human	24h	1.2333uM	EID0448

Response Information :

Types	Number	Response transcription factors
Up-regulation	96	GABPB1; SIAH2; PPARG; ADRB2; CRY1; BAZ1A; ZNF189; CEBPZ; E2F6; CCDC59; HDAC2; PCGF2; ORC2; DRAP1; ZNF443; MTDH; PHF2; CREB5; JAK2; NFIL3; ECD; ZNF263; NEDD8; PCBD1; EED; TRIM32; MAX; MNDA; ZBTB24; ZNF672; RBM14; ZBTB11; MDM2; ETV5; BATF3; PIR; ELK3; SIM2; BMI1; RBBP5; HSF2; C1QBP; CD3D; BRPF1; ENO1; ING3; FOSL1; EDF1; JUN; MYCBP; EZH2; HCFC2; UBP1; MED24; DNAJC1; FOSB; HOXA5; BBX; MITF; WWTR1; SUB1; NFAT5; IRF8; TRIM16; EMX2; ZBTB38; TRIM28; ING2; HEY1; FOXO3; SMARCA2; NCOA4; IRF4; EGR3; MSX1; HTATIP2; HOXC6; JARID2; BRD2; IKBKAP; TSC22D2; TLE4; NR2F2; CTR9; KLF4; TRIP6; TBPL1; BCLAF1; SPIB; FOXD1; MED1; HLTF; RFX5; KDM5D; BASP1; CDK7
Down-regulation	97	ZFP36L1; TRIB3; TSC22D3; CEBPD; TCF3; EPAS1; NCOA2; TFAP2A; HBP1; VGLL1; ZMYND8; MED12; JUP; IRF9; SOX13; MED14; ZNF423; VPS72; TCEA1; OVOL2; TXNIP; RING1; ERBB4; HOXD1; ZNF232; TAF9B; PBX1; ID4; ZNF331; TCF7L1; NR2F1; CEBPB; ID1; HOXD3; CBX7; KLF13; NFE2L2; ID3; SSBP2; NFATC4; CREB3L2; SPDEF; HMGB1; RBFOX2; SALL2; GFI1; CTBP1; SMAD6; ZNF24; TRPS1; FOXO1; ELF3; PBX3; MYCL; ZNF141; DDX17; ZNF573; ERG; TAL1; TRIM29; INSR; RAD21; DACH1; HES1; ZNF711; KLF3; TGFB1; PRDM2; CUX2; ZFP36L2; ZSCAN18; KLF5; PCGF3; TCF7L2; ZHX2; ZBTB16; ARID5B; ZNF264; TWIST1; PFDN5; MEIS1; TOX; ZNF117; FUBP1; ZNF532; ZNF91; ZBED2; PBXIP1; HMGN3; PDLIM1; IRF6; MEIS2; ST18; TFAP2C; SOX9; HIC2; MYBL1