Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID77200	Pevonedistat	GSE92742	NKDBA	Human	24h	3.7uM	EID0448

Response Information :

Types	Number	Response transcription factors
Up-regulation	31	CREB5; FOXC1; MAFF; NR1H2; BCL6; C1QBP; PIR; FOSL2; NFIL3; JAK2; BBX; HEY1; ETV5; KAT6B; IFI16; OSR2; WWTR1; EMX2; IRF8; FOXF2; CUX1; PEG3; BAZ1A; MXI1; MSX1; SNAI2; FOSB; BRD4; FOXO3; ATF3; KDM5D
Down-regulation	59	TSC22D3; PTTG1; CBX5; USP22; CENPF; BRD8; EGR1; SUV39H1; FOXM1; XBP1; ZMIZ2; TLE1; ZNF688; HMGA2; HMGB2; ZNF302; CCNA2; TXNIP; ETS2; BTG1; SSBP3; PROX1; DDIT3; NFYC; NFE2; JUND; RBL2; CENPB; CEBPB; ZNF217; MEIS1; TCF7; TGFB1; FUBP1; MYCL; HES1; ZBTB18; HMGB3; ZNF83; EHF; TCF12; FOXN3; ID3; FOXA2; TAF9B; ID2; KLF2; TP53; ASCL1; DMTF1; LEF1; TRIM29; SMAD3; ZBTB16; SATB2; TOX3; SOX9; ARID5B; MYBL1