Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID77199	Pevonedistat	GSE92742	NKDBA	Human	24h	11.1uM	EID0448

Response Information :

Types	Number	Response transcription factors
Up-regulation	49	CREB5; PIR; HEY1; MTDH; MXI1; HLX; YBX3; RBBP5; MNDA; SOX4; BRD2; LPIN2; SIAH2; NFAT5; ZNF136; PEG3; IRF4; NFIL3; ZNF426; PSMC3IP; SPEN; CREM; FOXO3; IFI16; TP63; FOS; E2F3; C1QBP; BAZ1A; ISL1; FOSL2; EMX2; ZFPM2; TLE4; BBX; ZNF394; ZIC1; WWTR1; STAT1; TBPL1; ZBTB38; MEOX2; NR2F2; HOXA10; WT1; POU2AF1; MSX1; BHLHE41; CDK7
Down-regulation	55	TSC22D3; CBX5; PTTG1; CENPF; XBP1; HMGA2; PRRX2; FOXM1; CCNA2; SUV39H1; DNMT1; SOX13; DACH1; HDAC7; TFAP2C; CEBPB; ZMYND8; NONO; MYCN; EGR1; FOSL1; CREB3L2; WHSC1; PITX2; SREBF1; TCEA1; CENPB; TXNIP; TSC22D1; PBX1; ZFP36L2; HMGB2; DDIT3; MKL2; RBFOX2; HMGB1; TBL1XR1; CHD9; FUBP1; ETS2; ID3; DDX17; ERBB2; SOX9; HES1; ZNF532; DMTF1; BTG1; MYBL1; ID1; HLTF; ZMIZ1; SMAD3; ID2; LEF1