Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID77189	Menadione	GSE92742	NKDBA	Human	24h	1.2906uM	EID0446

Response Information :

Types	Number	Response transcription factors
Up-regulation	160	SP110; CCNA2; HOXC6; NEDD8; PSPC1; TBP; NFKBIA; IRX5; BCLAF1; BRD8; ING2; PPARG; BHLHE40; CDK8; CASZ1; CNOT1; AFF1; BATF3; MAGED1; NCOA6; NFKB1; ING3; DPF2; TSC22D2; MED1; ELK1; BMI1; SND1; SOX4; TBL1X; ERBB2; MSX1; ORC2; TCEB2; ZBTB18; KDM2A; SNIP1; SUV39H1; TAF1D; HLTF; DRAP1; TSC22D1; PHF8; NFAT5; MYCBP; DDX5; DNMT3B; MYC; ZNF302; ZBTB24; ELK3; HTATIP2; RBBP7; COPS2; NFKB2; NR2F2; BRD2; BRPF1; EDF1; LPIN2; DNAJC1; ZNF410; CREG1; PIR; SREBF1; HMG20A; RUNX3; SNW1; KAT5; MMS19; ZNF23; HOXA7; ZNF184; KAT7; FHL2; RNF14; PMF1; NPAT; ZMYM2; RNF141; CTR9; RBBP4; TRIM32; TCERG1; MED23; MYB; RNF10; TAL1; PCGF2; EMX2; SAP18; KAT6B; BRCA1; MAF; MED24; TBL1XR1; SP100; REST; JARID2; PUF60; GTF3A; ZNF721; ZNF148; IKZF1; SSRP1; PHF20; TCF7; EZH2; ERG; SMAD3; ENO1; KAT6A; BASP1; WHSC1; RBM14; TSC22D3; NCOA4; HSBP1; SCAND1; TLE1; NUP62; SMARCE1; ELF1; YWHAB; HMG20B; VGLL4; SMAD1; KLF6; NFIB; RUVBL2; CRK; HOXA5; MAFB; USF2; ID2; BIRC2; TP53; RHOA; ATF4; SSX1; ZNF160; NONO; TRIM28; LEF1; ZBTB38; RBPJ; FOSL1; ZNF146; HOXA10; CARHSP1; TCF4; SATB2; HOXB7; MAZ; ZMYND8; HMGB3; HNRNPD; NCOR2; HOXB6; PAX8
Down-regulation	141	MYBL1; TFAP2A; HDAC9; PRDM14; TOX; SRY; ATN1; ZIC3; TRIB3; SIX3; TERF1; SOX13; SOX3; MEIS2; ZNF91; ZNF232; SOX2; ZNF93; ERBB4; LIN28A; GMNN; TTF2; NANOG; NCOA3; SNAI2; SOX17; TRPS1; BARX1; SUPT3H; VAX2; ZNF665; TCF7L1; ZNF331; RAD21; ETS1; ARNT2; FOXF2; KLF3; NAB2; OLIG2; CAPN15; ZNF117; MBD1; ST18; ZHX2; PRRX1; MECP2; ZNF589; RBFOX2; ZNF195; TP63; TFDP1; HIPK1; EMX1; CBX4; TFAP2C; TAF5L; CDIP1; TEAD4; LHX3; ERF; CDC5L; ZNF711; PRDM2; SALL2; ZNF43; TRIM29; CSDE1; GRHL2; THAP10; CEBPD; SOX10; ZNF85; MNDA; POU2AF1; MED17; IRF9; GATA6; CSDC2; CNOT3; E2F5; IRF6; ID3; VGLL1; ZSCAN18; PHIP; EN1; TRIM22; SPDEF; ZNF512B; TCEA1; CBFA2T3; BHLHE41; FOXG1; KAT2B; BPTF; ID4; NFATC4; CBX7; CUX2; ZNF423; CREBL2; ID1; BCL11A; HOXD1; TCF7L2; MYRF; IRF8; HIC2; BACH2; INSM1; ZNF239; TDP2; NR2F1; ELK4; HIRA; SSBP2; HEY1; KLF5; USP22; JAK2; SPIB; DLX5; JUP; ISL1; SHOX2; ZIC1; ARID1A; EHF; TGFB1; PAX5; SSBP3; PEG3; PITX1; INSR; ZBED2; HHEX; LITAF; NR4A2; SOX9; VPS72