Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID77154	Pyrvinium-pamoate	GSE92742	NKDBA	Human	24h	0.3704uM	EID0446

Response Information :

Types	Number	Response transcription factors
Up-regulation	195	PPARG; JARID2; NFAT5; BMI1; BATF3; KDM5A; DDIT3; MED1; PIAS2; HOXC6; XBP1; ORC2; TBL1X; TBP; HLTF; ATF1; NFIL3; ZFP64; BHLHE40; ARNTL2; LPIN2; TMF1; STAT5A; HABP4; PSPC1; BRD3; C1D; CNOT1; KAT7; DNAJC1; CTR9; NEDD8; CEBPZ; DRAP1; SNIP1; PIR; KLF12; MYC; CCDC59; TRIM32; AFF1; PHF20; SMAD2; SNW1; ZNF267; ZNF148; DPF2; GTF2IRD1; EGR3; ZMYM2; PHF8; ZNF84; ZMIZ2; ZBTB24; REST; ARID4A; FOSB; BBX; ZBTB11; NRBF2; NFATC3; RUNX3; MYB; MYCBP; POLR2A; ERBB2; ZZZ3; ING2; SETD3; NFKBIA; TOB1; MED7; HIVEP2; ASH2L; UBE2B; SMARCA2; FOXD1; NCOA6; CRY1; ZEB2; ZBTB38; BTAF1; FOXJ1; RNF111; KDM2A; PCGF2; ELF1; NR1D2; EDF1; CDYL; MAF; PPARGC1A; ZNF226; BRD8; MAFG; BRPF1; ZNF189; TRRAP; SMARCE1; FOXO4; FOXC1; TCEB2; TSC22D1; RREB1; CBX3; RNF6; ZNF443; MGA; ELK1; ZNF23; MSX1; ITGB3BP; HMG20A; ENO1; ERG; HSF2; RB1; BCLAF1; RBBP5; MAGED1; SIM2; CHD1; HSBP1; TSC22D3; NFIB; ATF4; FOXJ3; NCOA4; DDX5; SETD2; SP3; ATF2; RNF4; TRIM16; ADNP; TRIP6; SPEN; BRCA1; NFYC; E2F3; MITF; AHR; SREBF1; BCL10; HTATIP2; TP53; TBL1XR1; PBRM1; IKBKAP; RLF; ZBTB18; STAT3; MLX; ZNF468; NR1I2; NUP62; PLAGL1; TLE1; DNMT3B; ELF3; YWHAB; NR2F2; PSIP1; BIRC2; SOX4; HDAC6; EMX2; USF2; KDM5D; USP22; REPIN1; ELK3; NFE2L1; ETV5; STAT1; FHL2; CRK; RBPJ; VGLL4; HOXC10; CITED2; HOXB7; TBPL1; SMAD3; FOS; KAT6B; SCAND1; BAZ1A; LEF1; PAX8; BASP1; TRIM28; NCOR2; RHOA; HMGA2
Down-regulation	174	TFAP2A; NEUROD1; ZNF232; CEBPD; ZNF345; MEIS1; E2F4; ILF2; ATN1; MYBL1; ZFP36L2; CAPN15; ZSCAN9; ZNF180; UBE2L3; ZNF331; FOXM1; ZNF93; MEIS2; ZBTB44; ZNF682; TGIF2; ZIC3; NHLH2; BNC1; RAD21; ESRRG; GMNN; ZNF195; ZNF415; ZNF85; ZNF43; ZNF354A; CUX2; CNOT3; SRY; TCF7L1; ZNF665; BRWD1; CDIP1; SIX6; CALR; HLX; PIAS4; ZNF22; SOX13; HMGB1; BACH2; ZNF444; SOX11; RBFOX2; ZNF253; THAP7; PRDM2; AES; CDK9; PSMC3; ZNF91; SOX17; ETS1; LZTR1; SOX2; E2F5; SUMO1; IL16; CENPB; FOXN3; ATOH1; ZNF74; ING4; KLF3; RARG; LHX3; FOXF2; TAF9B; PEX14; CCNE1; ZNF589; TCF21; TOX; TULP3; MYBL2; PBX1; EN1; CDK2; CBX4; WNT4; INSM1; ZNF544; RING1; DNMT1; ZNF467; ZNF117; TGFB1; SOHLH2; PRRX1; BCL6; PBXIP1; TAF4B; HIRA; DMTF1; GRHL2; IRF6; SALL2; ZNF711; IRF9; SHOX2; SMARCB1; NR2F1; ZNF136; PBX3; NFATC4; REL; PAX6; CBFA2T3; HOXA1; ERBB4; TDP2; DLX2; HOXB13; TFAP2C; AEBP1; FUBP1; TCF7L2; TCF4; ISL1; IRF8; ZHX2; SLC2A4RG; ZNF512B; ZFPM2; GATA6; VPS72; VGLL1; FOXF1; GLI2; ZBED2; ID4; FOXA2; ST18; CAMTA1; E4F1; NKX2-1; PAX5; ZNF500; GTF2I; ZNF586; SPIB; ZIC1; TLE2; HIC2; DACH1; BCL11A; SSBP2; GATA2; TRPS1; THAP10; POU2AF1; NR4A2; TWIST1; PHIP; TXNIP; TBX3; ARID1A; ARID5B; SSBP3; SPDEF; SNAI2; ID1; ZSCAN18; E2F2; WT1; HHEX; HOXB2