Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID77147	Vorinostat	GSE92742	NKDBA	Human	24h	10uM	EID0446

Response Information :

Types	Number	Response transcription factors
Up-regulation	145	NEDD8; HLTF; CTR9; TSC22D1; SNIP1; RBBP5; ZSCAN5A; TBP; ORC2; FOXO4; ZBTB18; SND1; PIAS2; CRY1; JARID2; CEBPZ; SOX4; IKBKAP; TCEB2; RUVBL2; UBE2B; IKZF5; SMARCD3; TRIM16; MYCBP; SAP18; LPIN2; KDM5A; ING1; EED; CREG1; NFAT5; ECD; HDAC1; NR3C2; HOXA5; DPF2; HABP4; NPAT; BRD2; TSC22D4; PPARG; STAT1; RCOR1; NRBF2; TOB1; KAT7; ZBTB11; RUNX3; ASH2L; SETD3; CRK; TCFL5; CHD1; MXI1; ELK3; PHF20; ARID4A; EDF1; HDAC3; MLX; BHLHE40; ADRB2; SMARCA5; SMAD2; HCFC2; BBX; BRPF1; DRAP1; FOSL2; HDAC2; SIX1; ZKSCAN5; MED4; STAT3; RNF141; UIMC1; MED23; HSBP1; HSF2; SMAD5; PPARGC1A; MTF1; ATF3; ZNF189; POU3F1; SP110; HMG20B; THAP1; KDM2A; TBPL1; BCL3; BRD8; MYOD1; NCOA4; ING3; AFF1; PURA; ZHX3; RBM14; ID2; KLF2; TEAD1; TRRAP; ZNF14; ZNF212; RXRB; ZNF226; ZBTB40; ING2; RNF111; ZNF143; WWC1; ZNF783; HOXC6; ALX1; PSPC1; MED6; HOXA7; ITGB3BP; NCOA6; ZNF45; CDK8; TRIM32; ZNF468; HEY2; SREBF1; TBL1X; ZNF473; TSC22D2; MED1; KLF12; URI1; MGA; TAF10; NR1D2; SATB2; ZMYM2; MAGED1; MYT1; BRD3; BMI1; FOSB; CERS6; DMRT1
Down-regulation	176	FOXM1; IFI16; TRIB3; ATN1; E2F4; SOX21; NEUROD1; CCNA2; CDX1; SOX17; OVOL2; DCC; TFAP2A; HDGF; LHX2; TCF7L1; MYBL1; ZBTB7B; BNC1; ZIC3; HMGB1; ZFP36L2; MEIS2; SP140L; PRDM14; TEAD4; KLF3; HMGB2; ARL2BP; DEK; CAPN15; EWSR1; RAD21; TEF; BARX1; ZNF232; ZNF91; ZHX2; CEBPG; NEUROG2; POU6F2; CDIP1; FOXE1; SOX13; ZNF93; ZNF140; FOXB1; MAP3K10; CEBPD; FOXJ2; TCF3; ZNF219; LHX3; HMGA1; THRB; ATF5; ALX4; LIN28A; TRIM22; SOX14; TP73; ZNF180; SOX2; YBX3; ZNF264; TULP3; CDK9; ELF4; ARID3B; SOX18; VGLL1; PHIP; PAX6; PRDM1; ZNF154; CTCF; MBD3; CHD2; ZNF43; ETS1; ZNF85; DNMT1; HOXC8; TGFB1I1; ZNF141; TUB; AFF2; KAT2B; POU4F3; SMARCB1; FOXH1; ZNF665; FEZF2; E2F1; SUV39H1; ZNF117; NAB2; PRDM10; PROP1; FOXF2; TBX5; CBX2; FEV; ST18; EN1; KLF15; MYBL2; ZNF215; HMX1; HOXB1; ARNTL2; WDR77; PRRX1; EHF; HDAC9; PSMC3; ZNF345; TAF6L; HLX; PML; HEYL; POU2AF1; DDX17; ESR1; HOXA3; ZNF682; TFDP1; BACH1; ZNF22; HSF4; TOX; SRF; NEUROD2; ZNF33B; BRWD1; YEATS4; LMX1B; ZBED1; TP53; GRHL2; BNC2; ATOH1; CSDE1; ILF2; ELF5; SNAI2; ZNF74; NEUROD6; HIPK2; ZSCAN18; MYF6; ABL1; CENPF; PGR; GFI1; BCL11A; NCOR1; IRF9; SIX3; PRDM2; ZXDC; PTTG1; RBFOX2; RARG; ARID3A; TP63; TFAP2C; ZKSCAN8; MBD1; TTF2; CAMTA2; ID4; EMX1; ZNF136; CDK2; BRIP1