Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID77146	Pevonedistat	GSE92742	NKDBA	Human	24h	0.4111uM	EID0446

Response Information :

Types	Number	Response transcription factors
Up-regulation	216	CCNA2; PPARG; ORC2; EED; CEBPZ; TBP; PIR; HDAC2; HOXC6; BMI1; CCDC59; CRY1; RBM14; HLTF; JARID2; ZSCAN5A; TRIM32; MED27; PSPC1; PIAS2; TRIM16; NEDD8; BHLHE40; ZBTB18; CTR9; DPF2; BATF3; SFMBT1; MYC; MYB; KLF1; BCLAF1; SP110; PHF8; PSMC3IP; NFIL3; UIMC1; KDM2A; SNIP1; ZNF143; ZNF410; BRPF1; NPAT; CHAF1B; SUV39H1; RNF111; FHL5; RUVBL2; NR2F2; ZNF267; ZBTB11; MYCBP; ELK3; SNW1; ING2; SFPQ; C1D; TAF1D; DRAP1; TSC22D2; ZBTB24; LPIN2; ZNF443; MED6; MSX1; NFKBIA; SMARCA4; NCOA6; ZNF189; BTAF1; HSF2; PPRC1; ZNF200; MLX; POLR2A; AFF1; BAZ1A; MED4; RBBP4; NFKB1; BRCA1; MED1; MEF2A; YWHAB; TEAD1; SMARCA5; BRD3; HIVEP2; EDF1; MGA; KAT5; HMG20A; CDK8; ING3; SF1; TTF1; ERG; ZNF473; ATF1; KAT7; SETD3; E2F6; C1QBP; GABPB1; BRD2; TRIP4; ECD; HTATIP2; REST; ALX1; SMAD2; ZFP64; PLAGL2; HCFC2; TBL1X; NKX3-1; SAP30; CBX3; DR1; ASH2L; NUP62; ZNF23; SUB1; CRK; IKBKAP; TRRAP; PCGF2; FOXD1; SERTAD2; PATZ1; ZNF148; PMF1; EZH2; RBL1; SETD2; PA2G4; CHD1; RBBP5; NFAT5; FOSL1; SP100; RNF14; RLF; WHSC1; ZMIZ2; CENPF; DNMT3B; TRIM28; ENO1; COPS2; HNRNPD; PUF60; NELFB; BRD8; RB1; STAT5A; SIAH2; ELK1; SSRP1; PBRM1; TBL1XR1; MMS19; EMX2; MITF; ELF1; PIAS3; ZMYM2; SP3; XBP1; HSBP1; RNF10; SAP18; UBP1; RNF6; ERBB2; NFIB; IRF4; SMAD3; SMARCE1; MAFG; NFYC; MTDH; FOSB; HOXB7; BIRC2; CBFB; NCOA4; CCNC; MAFB; KDM5D; ATF4; TLE1; TBPL1; BASP1; SREBF1; SMARCA2; ZBTB38; MTF2; HOXC10; GTF3A; CREG1; RBPJ; HMGB3; WWTR1; RHOA; MNAT1; SPEN; KLF6; TP53; FOXJ3; YBX1; PAX8; MAGED1; HMG20B; HMGA2; HOXB6
Down-regulation	185	PRDM14; TFAP2A; TCEA2; NEUROD1; TERF1; KLF3; ZNF331; TRIB3; CEBPB; CEBPD; CDX1; ZNF345; ZNF665; SOX3; PRDM12; NCOA3; ZNF835; ZIC3; ZNF232; HBP1; TCF7L1; ATN1; RARG; NAB2; SRY; TOX; CDK9; ING4; ZNF141; TBX1; ZNF91; MEIS2; PRDM2; AES; BARX1; ZNF667; CDIP1; IRF3; SOX13; INSM1; RAD21; SOX2; ID4; ZNF682; ZNF43; JUP; ZHX2; MYBL1; SALL2; RING1; ZNF74; PBXIP1; ZNF611; TRPS1; PNRC1; ZNF195; MBD1; HSF1; ERBB4; LHX3; CBX4; ETS1; CALCOCO1; FOXG1; SOX18; ZNF573; RBFOX2; THRB; ZNF415; ZNF117; TP73; ZNF688; SUPT6H; TTF2; GRHL2; ZNF268; MYCN; ZNF75D; ZFP36L2; CREBL2; ZNF711; MEIS1; SNAI2; CAMTA2; GTF2I; ZNF580; ST18; ZNF816; HOXB13; PRRX1; LZTR1; BRWD1; WNT4; SMARCC2; KDM5C; DDIT3; DLX5; PITX1; TCF7L2; CENPB; IRF9; ZNF623; PHIP; FOXF2; PEG3; TWIST1; BCL11A; AEBP1; TULP3; NFATC4; CNOT3; FOXI1; EN1; SUPT3H; SOX17; TXNIP; ZNF589; ZNF219; ZNF264; CBFA2T3; ZMIZ1; ZSCAN18; CBX7; ZNF83; BHLHE41; OLIG2; NR4A2; LIN28A; HOXD1; PBX1; ZNF85; ACTL6B; EPAS1; NRIP1; SMARCB1; KLF13; ZNF500; CSDC2; BPTF; HDAC9; VGLL1; SSBP3; SOHLH2; GATA6; SOX9; GMNN; ID1; TFAP2C; ID3; TRIM22; THAP10; TAF9B; TGFB1; E2F5; THRA; TP63; ZIC1; BTG1; POU2AF1; TBX21; IRF6; DACH1; NFATC3; PAWR; ZBTB16; PAX6; PAX5; SSBP2; HEY1; INSR; EHF; TRIM29; TDP2; SPDEF; SHOX2; ASCL1; ZNF512B; CREB1; HIRA; TSC22D3; ZBED2; SPIB; CREM; VPS72; E2F2