Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID77145	Pevonedistat	GSE92742	NKDBA	Human	24h	1.2333uM	EID0446

Response Information :

Types	Number	Response transcription factors
Up-regulation	199	PPARG; HLTF; EED; IRX5; ORC2; NEDD8; MSX1; TRIM32; CEBPZ; MYB; DPF2; BHLHE40; ZNF189; CTR9; SAP30; BMI1; BATF3; ING3; PIR; MED27; ZNF267; CRY1; C1D; TRIM16; ZNF148; RBM14; ZSCAN5A; ZNF143; NCOA6; UIMC1; MYCBP; HDAC2; NPAT; SNW1; ZFP64; PATZ1; ING2; CCDC59; ZNF672; CCNA2; JARID2; PHF8; SFPQ; BAZ1B; TBP; TSC22D2; SNIP1; HMG20A; ASH2L; BRD2; KAT7; RBL1; SMARCA4; ZNF410; MYC; MLX; MGA; TRRAP; PHF20; CHAF1B; PLAGL2; HSBP1; EP400; CHD1; ZBTB24; E2F3; BCLAF1; NFAT5; SMAD2; LPIN2; AFF1; BRD3; PIAS2; RNF111; TAF1D; BRPF1; MED6; E2F6; DNAJC2; FOXD1; KLF1; PSMC3IP; PSPC1; KDM2A; TOB1; DRAP1; ZBTB43; TFAM; SUV39H1; ELK3; BRCA1; ZBTB11; MED1; TBL1X; CBX3; EZH2; REST; ZNF443; NFATC1; EDF1; ARID4A; BTAF1; PMF1; E2F8; SETD2; NR2F2; SFMBT1; YWHAB; SUB1; NFIL3; MAGED1; CDK8; MITF; RBBP4; ZEB2; TCERG1; HOXC6; PCGF2; HSF2; SMAD3; ENO1; RBBP5; BAZ1A; NUP62; SMARCD3; SREBF1; BBX; GABPB1; MED23; RNF6; MAFG; BRD8; ITGB3BP; KLF10; SAP18; IKBKAP; RB1; EMX2; HMGXB4; ATF1; MED7; ZNF23; TBPL1; SETD3; ERG; ZMYM2; RLF; PIAS3; ZBTB18; STAT5A; WWTR1; BCL10; MMS19; SMARCE1; ZNF587; BIRC2; XBP1; PBRM1; DNMT3B; ELK1; SP3; HTATIP2; FOXJ3; RUNX1; ZNF226; VEZF1; PUF60; LEF1; ETV5; KAT6B; NFYC; WHSC1; TRIM28; ERBB2; RNF4; SIAH2; BASP1; NCOA4; NKX3-1; HNRNPD; TGFB1I1; SMARCA2; ZBTB38; REPIN1; SIX1; GTF3A; CBFB; HMGB3; CRK; SCAND1; KDM5D; HOXB7; RFX5; ZNF217; MNAT1; HMG20B; MAFB; ESR1; HMGA2
Down-regulation	189	TFAP2A; ZNF835; ZNF665; ATN1; ZNF345; KLF3; ZIC3; MYBL1; NEUROD6; IRF3; TCF7L1; CEBPB; ZNF223; ZNF91; RARG; SOX13; NCOA3; PRDM14; CDX1; SOX21; ZNF117; CAPN15; ZNF232; ZNF253; ZFP36L2; HBP1; ZNF331; RAD21; TERF1; PRRX1; TCEA2; RING1; ZNF93; PNRC1; ZNF682; ZNF224; CDK9; ETS1; WNT4; ZNF141; ZNF43; IRF6; BRWD1; ZNF112; SOX3; DDX17; PRDM2; TRIB3; TP73; THRB; NAB2; LHX3; EPAS1; BARX1; ZNF816; ZNF667; SALL2; ID4; CSDC2; ZMYND11; MBD1; BTG1; TFAP2C; TRPS1; MLLT10; CDIP1; SP1; SOX2; RBFOX2; FOXN3; TCEA1; ZNF573; ZNF711; ZNF688; TOX; MYCN; TCF3; ZNF165; LIN28A; ZMIZ1; TAF9B; TRIM29; ZNF264; GTF2I; MEIS2; PHIP; JUND; EHF; ING4; IRF9; CAMTA2; IFI16; ZHX2; ZNF85; AES; TAF4B; SSBP3; CNOT3; PBX1; ZNF136; TGFB1; HSF1; TCF7L2; INSR; PBXIP1; KLF9; SUPT3H; JUP; SOX17; SNAI2; INSM1; PAWR; SOHLH2; E2F5; ZNF611; AEBP1; GATA6; CEBPD; EN1; STAT2; TXNIP; FOXF2; ERBB4; REL; MEIS1; FOXI1; ZNF195; MLXIP; KLF5; CSDE1; ZNF83; BCL11A; CREBL2; TSC22D3; TWIST1; CBX7; ST18; ZNF33B; HDGF; NFE2L2; VGLL1; ZSCAN18; ELK4; ZNF32; NFATC3; BHLHE41; NFATC4; GRHL2; PBX3; MYRF; SPDEF; KLF13; ZNF500; ID1; FUBP1; OSR2; HIRA; CTBP2; NR4A2; FOXG1; DACH1; BNC2; E4F1; PFDN5; KLF6; CBFA2T3; STAT1; NFE2L3; THAP10; NR2F1; LITAF; YAP1; PAX6; ARID1A; ZNF239; TP63; E2F2; ZIC1; SSBP2; DMTF1; PITX1; DLX5; ZNF512B; ISL1; TBX3; VPS72; CREM; SOX9; CITED2