Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID77144	Pevonedistat	GSE92742	NKDBA	Human	24h	3.7uM	EID0446

Response Information :

Types	Number	Response transcription factors
Up-regulation	100	CEBPZ; PIR; PPARG; ZNF410; MED27; BHLHE40; LPIN2; MYCBP; GTF2IRD1; TBL1X; MYC; CCDC59; TSC22D2; ING2; ECD; TRIM32; HDAC2; TBP; NPAT; ORC2; PSPC1; HLTF; PSMC3IP; SP110; NR2F2; ZNF143; SAP30; DPF2; SETD3; MAFG; DRAP1; ZFHX4; DNAJC2; HCFC2; BATF3; TAF1D; NFIB; RBPJ; NFYC; ZNF148; PHF8; GTF3A; SND1; MLX; EDF1; BRD2; RUNX3; JARID2; ZMYM2; MSX1; MXI1; ELK3; SERTAD2; CREB5; RBBP4; SIX1; MMS19; RNF10; YWHAB; MDFI; PCGF2; SMARCA4; SOX4; RLF; HSF2; CTR9; PUF60; NFAT5; SMAD3; ZNF281; BRD8; SUB1; SMAD2; FOXO3; FOXJ3; NFATC3; HTATIP2; KAT6B; BASP1; MTF2; TOB1; CRK; WHSC1; ATF3; BAZ1A; ZBTB38; EMX2; ZBTB18; MAFB; RYBP; ENO1; NUP62; HMG20B; HNRNPD; LEF1; ATF4; TLE1; SCAND1; HOXB6; KDM5D
Down-regulation	119	CDK9; ATN1; RAD21; TOX; ZNF665; LIN28A; CDX1; AEBP1; FOXM1; JUP; ZNF264; ZNF667; CAPN15; ZNF253; ZNF331; SOX13; PRDM2; CENPB; CEBPD; PNRC1; ZIC3; TERF1; MYBL1; CNOT3; ZNF552; TCEA2; SOX17; MEIS2; PBX1; ZMIZ1; ST18; ZNF816; ID4; ZHX2; HDAC9; TRIB3; TRPS1; SOX2; EHF; SMARCB1; ZFP36L2; INSM1; NANOG; TFAP2A; ZNF623; ILF2; TSC22D3; MYRF; GRHL2; CALR; TFAP2C; CREBL2; TCF21; ZSCAN18; ZNF551; CBX7; ZNF83; PBXIP1; PBX3; NRIP1; KAT2B; BCL11B; ZNF91; ZNF117; FOXF2; ETS1; TCF7L1; FOXG1; CDIP1; BCL11A; TGFB1; NFATC4; MYCL; HMGA1; TCEA1; E2F5; GTF2I; THAP10; VGLL1; GATA6; SALL2; THRA; HMGB2; SSBP3; SOHLH2; ZBED2; PRRX1; HOXD3; PHIP; ERBB4; EPAS1; TP63; HOXD1; ZNF43; USP22; SSBP2; IRF6; HMGN3; MLXIP; SOX9; BTG1; PAX6; ATF5; CBFA2T3; DLX5; SOX11; ID1; DACH1; FOS; IRF9; SPDEF; AHR; TOX3; TXNIP; LITAF; PEG3; E2F2; CRYM; VPS72