Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID77143	Pevonedistat	GSE92742	NKDBA	Human	24h	11.1uM	EID0446

Response Information :

Types	Number	Response transcription factors
Up-regulation	106	CEBPZ; PIR; HOXC6; TCFL5; ZNF143; TEAD1; MYCBP; PPARG; TMF1; HABP4; ZNF410; NR2F2; C1D; ORC2; CRY1; TSC22D2; SALL1; SP110; SOX4; PSMC3IP; HDAC2; MITF; ZNF200; ZNF189; CREB5; RBBP5; ING2; UBE3A; MYC; ZNF226; SNIP1; ZBTB24; TBL1X; PCGF2; CTR9; TOB1; NFIB; LPIN2; PHF8; BATF3; SAP30; MAFG; HDAC1; MSX1; RBPJ; DPF2; JARID2; RBPMS; ZNF148; AR; E2F3; RLF; BRD2; ZNF721; DRAP1; MXI1; ZMYM2; FOXO3; NRBF2; ESR1; PHF20; BRD3; MTA1; ZBTB18; SP3; EMX2; REST; BANP; TBPL1; HOXA5; SIAH2; GTF3A; NKX2-1; MTF2; NFIL3; MLX; EDF1; RORA; HOXB6; MAF; WWTR1; CITED2; BBX; ATF1; BRD8; SMAD2; PPARGC1A; ENO1; MYB; BAZ1A; EZH2; RYBP; SMARCE1; CRK; YWHAB; BIRC2; SMAD3; HMG20B; LEF1; ELK3; NUP62; HOXB5; TLE1; HNRNPD; HOXB7; KDM5D
Down-regulation	117	CEBPB; PPP1R13L; ILF2; RBFOX2; CDX1; CBX5; TFAP2A; RARG; ZNF331; SOX13; NCOA3; WNT4; KLF3; ZBED2; MYBL1; TCEA2; FOXM1; TOX; SIX3; PLAG1; ATF6; NFE2L2; TAF9B; VGLL1; CBFA2T2; FOXN3; SUPT6H; ATOH1; BTG1; ID4; RAD21; DDX17; EHF; EHMT2; PITX2; ZMYND11; PURA; IRF9; CENPB; TRIM29; HBP1; KLF5; JUNB; MYRF; ZHX2; JUP; ZNF117; EPAS1; AEBP1; TERF2; CCNA2; TFAP2C; ZNF33B; ZNF711; CBX7; HMGB1; SOX17; FOXF2; PRRX1; IRF6; ZNF665; SSBP2; CDIP1; DACH1; CBX4; HIRA; ETS1; PTTG1; TCF7L2; RXRA; ZFP36L2; GTF2I; RBL2; TCEA1; CNOT3; TCF21; TRPS1; VDR; NR1H3; ZSCAN18; BCL11A; GATA6; GMNN; TSC22D3; TFCP2; ZKSCAN1; FUBP1; MEIS2; TXNIP; TP63; SOX2; ID3; CENPF; ZNF195; TGFB1; ZNF83; PBX1; ZNF43; CTBP2; NFATC4; NRIP1; CREB3L2; SSBP3; ZMIZ1; SOX9; POU2AF1; PITX1; RFX5; DLX5; DMTF1; MKL2; PAX6; SOX11; EGR1; ID1; VPS72; ERBB4