Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID77091	Pevonedistat	GSE92742	NKDBA	Human	24h	0.4111uM	EID0447

Response Information :

Types	Number	Response transcription factors
Up-regulation	201	PPARG; IRX5; CCNA2; ORC2; MEF2A; PSMC3IP; RBM14; SIAH2; NFIL3; TRIM16; GATA4; HOXC6; ALX1; EED; NRF1; CREG1; HDAC2; NFKBIB; ZBTB18; CRY1; HOXC10; ING3; RB1; STAT5B; MED6; HLTF; BMI1; CHD1; TTF1; CRK; BRCA1; ZNF267; STAT5A; SFMBT1; ZBTB32; BATF; BATF3; TBP; ZNF443; NFKB1; HIVEP2; POLR2A; CCDC59; PIR; CTR9; HABP4; GABPB1; EDF1; BLM; HMGA2; IRF4; ZSCAN5A; ELK3; RUVBL2; BHLHE40; KAT7; CHAF1B; TRIP6; SETD3; MLX; DDX54; PSPC1; HSF2; RUNX1; UBP1; MTA1; NPAT; PRRX2; SUV39H1; ZNF473; RUNX3; HMG20A; TRIP4; PHF2; MTDH; C1QBP; TEAD1; ZBTB24; ARNTL2; MED1; NKX3-1; BCLAF1; NEDD8; KDM2A; E2F6; CARM1; SF1; ZNF200; ING2; UBE3A; NFATC1; TAF1D; ASH2L; MYC; MNAT1; RNF14; ATF1; ZNF593; RELB; NUP62; SMARCA4; PUF60; NR2F2; RNF111; BAZ1B; ECD; FOXL2; JARID2; TSC22D2; NFKBIA; PLAGL2; DNMT3B; ZNF143; KLF12; TRIM28; SP110; FOSL1; DRAP1; IKBKAP; BRPF1; IRF5; CBX3; PA2G4; PREB; FOSB; HMGA1; MGA; DPF2; FOXD1; ZBTB38; ARID4A; SSRP1; TRRAP; MSX1; SNW1; PPRC1; RBBP4; EZH2; ZNF672; GCFC2; PHF8; HTATIP2; TRIM32; BRD2; ZEB2; CENPF; ELF1; ZNF410; SNIP1; AATF; NCOA6; NAB1; COPS2; ITGB3BP; KLF6; BAZ1A; BRD3; ERG; ZBTB11; WHSC1; KAT5; IRF7; ELK1; WWTR1; ETV5; SFPQ; PCGF2; GATA3; AFF1; RNF6; ENO1; BASP1; PBRM1; MYB; SMARCA2; MAFB; EYA2; FOXO3; MED24; SMAD2; BCL3; LPIN2; ZMIZ2; MECOM; YWHAB; JUN; SUB1; HOXB7; SP3; CBFB; RFX5; STAT6; TAF10; KLF2; MITF; EMX2; TBPL1; CREB3L1; CTNNB1; RBPMS; KDM5D
Down-regulation	167	TFAP2A; ARNT2; CARF; HOXD1; CEBPD; TRIB3; MED14; PRDM14; ZNF83; IKZF3; ZNF195; LIN28A; SOX3; ZNF345; CEBPB; ZBTB16; ZNF611; NEUROD1; FOXG1; CHD2; MYBL1; PNRC1; BPTF; INSR; ZNF74; CALCOCO1; TCF7L1; SRY; HBP1; ZNF682; ZNF623; ZNF711; ZNF232; SOX18; ZNF354A; POU2F3; NR1H4; ZIC3; ZNF440; ING4; CERS4; PRDM12; ZFPM2; HOXB1; ZNF91; TERF1; TCEA2; ZNF665; FEZF2; HIRA; ETS1; TXNIP; SOX11; ZFP36L2; TSC22D3; ID1; ZMIZ1; RARG; ZNF117; ZNF675; JUP; NFATC4; ZFP69B; ZNF141; OLIG2; TBX1; ZNF12; ZNF652; KLF3; ZNF701; ZNF415; AES; ID4; SOX13; EPAS1; BCL11A; ZNF573; ZNF133; NCOA3; ERBB4; ZNF43; ZNF350; ZNF224; SALL2; BTG1; ZNF75D; ZNF331; NFATC3; TCF4; DDX17; ZBTB20; CBFA2T2; BACH2; ASCL1; BARX1; SOHLH2; MEIS2; EN1; INSM1; MEOX1; TTF2; WT1; ST18; ZNF667; ZNF500; ZNF273; TOX; PHIP; PCGF3; ZNF160; ZNF44; HOXB2; TCF7L2; SMAD1; ZNF580; ZNF85; GRHL2; ZHX2; PITX1; ZNF589; SOX10; ZNF165; CBFA2T3; ZNF93; PEG3; MEIS1; MYCN; MLXIP; CTBP2; LHX3; SOX17; CDIP1; SNAI2; KLF11; PBXIP1; FOXF2; ZNF721; NFE2; SPDEF; PFDN5; KDM5C; TRPS1; IRF9; SOX2; POU2AF1; PBX3; ZNF264; ID3; HDAC9; HEY1; AEBP1; KLF13; PSMC3; TOX3; PLAGL1; VPS72; PBX1; PAWR; CREB1; EGR2; ZKSCAN1; NR4A2; TGFB1; ZSCAN18; TFAP2C; IRF6; PAX6