Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID77090	Pevonedistat	GSE92742	NKDBA	Human	24h	1.2333uM	EID0447

Response Information :

Types	Number	Response transcription factors
Up-regulation	178	PPARG; EED; MED27; NFKBIB; HLTF; HDAC2; CREG1; ALX1; ING3; RB1; CRY1; LEF1; ZNF282; FOXD1; MSX1; ORC2; BHLHE40; BRCA1; CHD1; ZNF148; RBM14; TTF1; SIAH2; TRIM16; JAK2; TFAM; ASH2L; DPF2; TRRAP; ZNF267; MGA; RCOR1; PSMC3IP; HABP4; SNW1; MEF2A; HAND1; KAT6B; ZNF384; CTR9; NEDD8; MYCBP; HMGA2; BATF3; DNAJC2; NFATC1; PIR; CHAF1B; ITGB3BP; BRD2; ZNF143; ZNF764; TAF1D; NCOA6; EZH2; DDX54; RFX5; KAT7; ZFP64; CBX3; BMI1; C1D; EP400; EDF1; BRF2; SAP30; GCFC2; HOXC10; BBX; FOXJ3; STAT5A; ZNF189; HOXC4; MTA1; SFMBT1; ENO1; LHX6; SUV39H1; ZBTB24; ZNF443; E2F3; HMGA1; TOB1; IRF5; ING2; MNAT1; SMARCA4; ZNF337; NPAT; PLAGL2; ELK3; CHD3; DRAP1; TCERG1; HSF2; MLX; GABPB1; CCDC59; MITF; SFPQ; BAZ1B; RELA; HIVEP2; TSC22D2; TRIM32; KLF12; MAFG; SMARCA2; BAZ1A; SMARCD3; ETV5; EMX2; TBP; MYB; IKBKAP; SP3; ZFHX4; MED6; PHF8; ZNF672; REPIN1; PATZ1; ATF1; SETD2; CCNA2; RNF6; SUB1; BCLAF1; BRD3; KDM2A; SIX1; MYC; RBBP4; SNIP1; ZEB2; C1QBP; HIVEP1; ZNF217; JARID2; TRIP6; HSBP1; EYA1; ZBTB11; NFAT5; ZNF394; SMARCA1; NUP62; BRPF1; SMAD7; RUNX3; NKX3-1; SREBF1; PHF20; BCL10; PCGF2; EYA2; ISL1; TRIM28; SP100; ZNF432; HTATIP2; HOXC6; SMAD2; AFF1; PITX1; HDAC1; MED24; BRD8; TBPL1; ZBTB38; CTNNB1; YWHAB; LPIN2; ATF3; BIRC2; NR2F2; HOXB7; KDM5D
Down-regulation	142	INSR; EPAS1; PRRX1; IRF3; CERS4; BTG1; CARF; CEBPB; HBP1; ZNF835; FOXO1; TSC22D3; SP1; ZNF688; CSDC2; PBX3; ZNF83; RARG; RAD21; CHD8; LIN28A; ZNF224; ETS1; ZMIZ1; ZIC3; PNRC1; NKX2-1; ZNF665; FOXN3; MED14; ZFP36L2; BPTF; ZFPM2; TFAP2A; CITED2; ETS2; HOXD1; ZNF91; SOX13; BNC2; DDX17; EN1; CNOT3; ZBTB16; MYBL1; TCF7L1; ZNF345; ZNF117; CEBPD; TRIB3; ZNF573; GTF2I; ZNF675; CHD9; ZNF253; WNT4; ZNF623; ZNF611; ZNF652; ZNF93; ESRRG; KLF3; TRPS1; SOX3; ZNF682; SALL2; ID4; NFATC3; NCOA3; ATN1; ZNF232; ZNF331; PAWR; UBE2I; NEUROD1; IFI16; ZNF141; TFAP2C; TCF7L2; SOX18; AEBP1; INSM1; HIRA; CTBP2; ZNF33B; ZNF580; ZHX2; PITX2; TCEA2; IRF6; MED13; MLXIP; NR4A2; CREB3L2; MXI1; ZNF44; ASCL1; SPDEF; ZNF264; IRF9; ERBB4; ZNF165; NFE2L2; ZNF430; ZNF85; ZNF43; DACH1; REL; FOXE1; KLF4; ID1; GATA6; E2F5; PBX1; STAT1; KLF6; TRIM29; KLF5; TGFB1; PBXIP1; OSR2; TAF9B; MEIS1; LHX3; MEIS2; YAP1; ARID1A; EHF; CDIP1; SOX17; SOX2; TERF2; SOX11; VPS72; NR1H2; FLNA; ZIC1; CREB1; ST18; CBFA2T3; NR4A1; EGR1