Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID77089	Pevonedistat	GSE92742	NKDBA	Human	24h	3.7uM	EID0447

Response Information :

Types	Number	Response transcription factors
Up-regulation	183	IRX5; PPARG; ECD; ALX1; ORC2; HDAC2; CCDC59; EDF1; MYOD1; ING3; SIAH2; HLTF; BATF; RBM14; GTF2IRD1; HMG20A; CHAF1B; NFYC; PSMC3IP; HABP4; RUNX3; TSC22D2; UIMC1; MYCBP; FOXJ3; NPAT; EED; RB1; TEAD1; PIR; KAT6B; SMAD5; EMX2; CHD1; KLF12; MEF2A; CEBPZ; BAZ1B; ZNF148; MAFG; BRD2; ZNF443; MSX1; SMAD7; NFKBIB; STAT5B; TAF1D; FOXD1; NFIC; TBL1X; BLM; BHLHE40; SFMBT1; SETD3; PURA; CARM1; TRIM16; STAT5A; MXI1; ING2; DNAJC2; TBP; ZNF267; ZNF410; BATF3; ZBTB38; SMAD2; CTR9; NFAT5; E2F6; MLX; JAK2; PCBD1; DNAJC1; HMBOX1; TRIM32; BMI1; MED6; TRIP6; DDX54; CRY1; ZBTB11; MYC; RUNX1; LPIN2; NFATC1; IKBKAP; ASH2L; ZBTB24; YAF2; MSC; COPS2; ZNF143; TFAM; CASZ1; SMARCA2; ZNF281; HOXC10; TSC22D4; SP110; PPRC1; PIAS2; SIX1; SETD2; CRK; SMARCA4; HSF2; USP16; CHD3; BRPF1; HIVEP2; ITGB3BP; MED1; HCFC2; SCMH1; DRAP1; ARID4A; CREB5; ZFHX4; PSPC1; ZFP64; NCOA6; RBL2; EYA2; SAP18; BBX; KAT7; SNIP1; ZNF672; BCLAF1; EYA1; SP100; SOX4; ELK3; ETV5; KDM2A; SERTAD2; ZBTB18; PPARGC1A; NFATC3; UBP1; KLF9; ZNF189; NR2F2; NUP62; PCGF2; GABPB1; HOXC6; PATZ1; NCOR2; JARID2; EZH2; LEF1; NCOA4; SP3; FOXO3; KLF2; HEY1; IRF7; YWHAB; BASP1; MED24; ZEB2; BCL3; IRF4; BAZ1A; BRD3; ZMYM2; TAF10; SIX2; RBBP4; FOXC1; GTF3A; ATF1; KDM5D; ATF4; SUB1; CREB3L1; TWIST1; TBPL1; PHF20; SPEN; ESR1
Down-regulation	173	LIN28A; ATF5; ARNT2; ZFPM2; MYBL1; TRIB3; ILF2; CEBPD; HOXD1; RAD21; PRDM14; TSC22D3; PBX3; ZNF623; ZNF816; IRF3; HOXD3; TFAP2A; ZNF492; ZMIZ1; GRHL2; NANOG; ZNF74; ID4; EPAS1; ZNF345; SRY; POU5F1B; TOX; POU2F3; ZNF83; ZNF211; MED14; JUP; TFAP2C; SOX13; ZIC3; ZNF682; ZNF224; CTBP2; SUPT3H; PBX1; PNRC1; BTG1; TCF21; ATN1; NFATC4; TRPS1; YBX3; FOXM1; ZBTB16; ZNF665; SMARCB1; PRDM2; TCF7L1; FEZF2; EHF; HDAC9; MEIS2; NR1H4; FOXF1; RBFOX2; ZNF180; CNOT3; ZNF611; AEBP1; ZNF354A; HMGB3; ID1; ZNF215; ZNF675; NEUROG2; ENY2; ZNF573; ZNF667; ZNF219; EN1; ZNF12; ETS1; ZNF75D; ZNF93; TDP2; CDK9; ST18; ZNF232; VGLL1; SOX3; NEUROD1; ZNF532; ZNF195; HIRA; BCL11A; PRPF6; ZNF264; AHR; ZNF701; SOX17; ZFP36L2; WT1; SOX10; SOX11; ZNF551; ZBTB20; ZNF711; TCEA2; ZNF544; ZNF141; PRRX1; FOXF2; NKX2-2; SOX18; SPDEF; TCF7L2; PQBP1; SALL2; PSMC3; POLR3C; FOXE1; ZNF117; NR5A2; MLXIP; TP63; PITX1; HHEX; ZBED2; INSM1; GMNN; MYCL; PHIP; ZNF91; FOXI1; KAT2B; INSR; NCOA3; ZNF331; CALR; PBXIP1; SOHLH2; E2F5; PTTG1; ZHX2; FOXN3; WNT4; GATA6; TCF4; SOX2; KDM5C; ZNF589; PEG3; ZSCAN18; TAF9B; MYRF; ZNF415; PAWR; ZNF43; TULP3; IRF6; HOXB2; NR4A2; NFE2L3; EGR2; ID3; NR1H2; PAX6; TLE4; BACH2; HMGN3; VPS72; TGFB1; TXNIP; ERBB4; EGR1; E2F2