Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID77088	Pevonedistat	GSE92742	NKDBA	Human	24h	11.1uM	EID0447

Response Information :

Types	Number	Response transcription factors
Up-regulation	114	TBX2; MXI1; CRY1; HABP4; ZNF516; SIAH2; TEAD1; PSMC3IP; MSX1; AHR; NFIL3; UIMC1; SOX4; CREB5; SALL1; ZBTB43; FOSL2; ORC2; MTA1; BHLHE40; CITED2; ZNF410; TSC22D2; CHD1; HOXC4; HEY1; SMAD5; UBE3A; ENO1; TMF1; HSF2; NR2F2; MNAT1; ZNF384; HOXC10; TBX21; MYCBP; MAFG; BATF3; POLR2A; MITF; EMX2; ZNF226; ZNF143; NRBF2; FOXO3; RORA; PCGF2; KLF12; ARID4A; CRK; NFIB; SAP18; MED6; PIR; ZNF593; HIPK1; ZFHX4; MSC; SFMBT1; STAT5A; GATA3; SETD2; KAT7; PAX8; SPEN; MGA; MEIS1; EDF1; KLF2; EZH2; ESR1; TCERG1; KLF6; BBX; RBBP5; BRD2; NKRF; ATF3; NFAT5; NFATC3; PHF8; GABPB1; HTATIP2; HDAC1; SP100; ATF1; FOXC1; CTR9; HLTF; ZMIZ2; HOXC6; TOB1; BRD3; CREM; MYC; ETV5; JUN; ZBTB18; SMARCA2; JARID2; ARID5B; HOXA5; ZEB2; LPIN2; BAZ1A; ZBTB38; ZIC1; TBPL1; CREB3L1; NUP62; IRF7; CTNNB1; HOXB6
Down-regulation	138	ZNF302; CEBPB; ZMIZ1; HOXD3; ILF2; PLAG1; HOXD1; ATF6; TERF1; CEBPG; ZFP36L2; NFYB; ZNF623; MKL2; BTG1; TSC22D3; JUP; CBFA2T2; CBX5; HOXB1; EN1; CTCF; ID4; ZNF83; CDX1; ZNF33B; TRIM29; RBFOX2; HIRA; HMGB1; CENPF; CREB3L2; TFAP2A; PBX3; ZNF532; SIX3; ZNF345; SOX13; RARG; SMAD1; ID1; VGLL1; CCNA2; TRIB3; DDX17; SUPT3H; ZBED2; PITX2; TOX; ZKSCAN1; MDM4; TAF9B; ZNF711; WNT4; RAD21; TFAP2C; POU2AF1; HDAC9; ZBTB20; BPTF; ZNF665; CTBP2; BCL11A; TULP4; MED20; EHF; E2F5; HBP1; DACH1; SMARCB1; BACH2; BASP1; MYBL1; GTF2A2; FOXE1; TCF4; TCEA2; CBX7; ZNF331; GATA6; TRPS1; NFE2L2; ZNF273; ZNF117; TCF7L1; PTTG1; ZBTB16; TCF12; ZHX2; FOXO1; PITX1; NCOA3; ZNF93; SERTAD2; SOX11; FOXN3; ZNF232; ZSCAN18; ZNF652; ZNF415; DMTF1; ZNF611; ZNF43; ZEB1; PBX1; STAT3; ID3; CUX2; ZNF430; SCAND1; ZNF91; KLF5; TERF2; HIC2; ZNF423; TLE2; SOX17; ST18; TCF7L2; TXNIP; KLF11; PLAGL1; IRF9; CREB1; ZMYND8; MYRF; JUNB; FOXF2; PHIP; IRF6; SOX2; SSBP2; STAT1; VDR; HES1; EGR1; MAFB; HHEX