Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID77077	Menadione	GSE92742	NKDBA	Human	24h	11.6157uM	EID0445

Response Information :

Types	Number	Response transcription factors
Up-regulation	132	LMO1; CRTC1; KAT5; TLE4; PLAG1; NR1H4; TADA3; TUB; GATAD2A; PIAS3; GATA2; IRF8; IRF3; IKBKAP; SCAI; CIZ1; HDAC11; ZNF14; PLAGL1; NFIC; MED25; PUF60; JUNB; WNT4; SHOX2; GLI2; ZNF770; HINFP; ZNF580; HIPK1; ZNF611; NR2F1; ZBTB20; ZNF8; ZIC3; KLF1; NR1H2; CDK7; PAX6; NPM1; TCF21; SIX6; ZBTB43; ZBTB32; SPDEF; RORA; TAF6; NCOR2; ETS1; YBX2; GTF2F1; HDAC3; GATA1; CASZ1; BNC2; ZNF44; MEIS1; ARID4B; NELFB; PCBD1; CTBP1; TAL1; ZNF721; FOXA2; ZNF506; IFI16; ZNF148; RBPMS; FOXN3; ZNF160; POU2F1; LEF1; WIZ; ZBTB38; STAT4; IRF1; ZNF711; BACH2; CHD9; IRF2; NR3C2; AR; INSM1; PBX1; IRF9; ZNF91; NR4A1; MEIS2; PITX1; ZNF589; TRIM32; ZNF652; PEG3; FOXO4; ZNF219; TCF4; MYC; ZEB1; HMG20B; TSC22D3; TCF7; ZFPM2; HIVEP1; THAP11; DMTF1; XBP1; SUV39H1; CNOT2; VGLL4; FOXE1; EGR2; SALL2; HDGF; TXNIP; CERS4; SMARCD3; KLF13; ATF1; CREB3L2; ZBED2; TGFB1; FHL2; TRIM29; FOXO1; SP3; JARID2; TBL1X; INSR; BCL11B; EMX2; NR2F6; TRIB3
Down-regulation	176	PARP1; TCEA2; SAP30; BANP; PRPF6; SMARCA2; CNOT1; ZNF239; PRKDC; POU3F2; YEATS2; ZNF302; ZNF593; HEY2; E2F2; TBPL1; AHR; E2F3; ZNF544; ZNF165; HMGA1; ZSCAN18; ENO1; SREBF2; ORC2; KAT6B; BIRC2; URI1; TBL1XR1; RFC1; ARNT2; WDR77; ZNF512B; KLF6; CSDE1; SMARCC1; RBBP4; TAF4; GMEB2; CNOT6; TOPORS; MSX1; ZFHX3; ZNF281; KMT5A; ZNF93; TOX; MED23; ZNF195; C1QBP; PHF20; YWHAB; MNDA; CREM; MED20; MLLT10; NFYB; CENPF; BRD7; TTF2; MAFF; ARL2BP; DR1; COPS5; CITED2; JAK2; ZBTB48; CCNH; MAFB; TCF7L1; CALR; PEX2; PMS1; FOSL2; TOB1; CCNC; RNF6; C1D; MTF2; DAXX; THRAP3; MBD2; ARID5B; FOXD1; CDK2; CBX5; TP53; MECOM; CREB5; SFPQ; TAF1D; ATF3; GCFC2; TCEA1; ELF1; PQBP1; CTBP2; EYA2; ZNF140; HDAC9; CRYM; FOXC1; ERBB4; NCOA6; FOS; TFCP2; PSPC1; RNF138; PHIP; FUBP1; ERG; USP22; ARID1A; ENY2; BTAF1; CEBPD; SNAI2; HOXA10; PIR; ZBED4; ETS2; ID4; SOX9; TP63; MNAT1; BHLHE41; PRRX1; ZBTB18; ASH2L; HIF1A; CTNNB1; SMAD4; FLI1; IRF7; REPIN1; TAF9B; ZNF532; DLX5; TRAK1; MITF; GMNN; HDAC2; MYBL1; CBFB; HDAC4; ELF3; SP110; ZBTB16; HOXB7; SIAH2; HOXC6; SMAD3; AEBP1; ZMYM2; NCOA1; FOXJ3; SP100; IRF6; LMCD1; ZSCAN31; HDAC1; GRHL2; ZFP36L2; CREB1; BAZ1A; ZMYND8; TSC22D1; EYA1; HOXC10; STAT3; ZIC1; TWIST1; FOSB; ID1; DNMT1; EGR1