Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID77061	Naltrexone	GSE92742	NKDBA	Human	24h	0.3704uM	EID0445

Response Information :

Types	Number	Response transcription factors
Up-regulation	225	BBX; ZNF124; RBBP8; EGR3; MTF2; NFAT5; ZNF329; ZSCAN18; PHF20; SAP30; DMTF1; ZZZ3; ZFP30; MTDH; TFAM; SMAD5; CHD1; MDM4; STAT1; BCL10; NKX3-1; SIX1; EGR2; NRIP1; KDM5A; HOXD1; ZNF606; TDP2; RBL2; CREBL2; DEK; UBTF; ATF1; CBX3; USP22; RNF6; MEOX2; PLAGL1; TRIM22; TSC22D3; ENY2; TEAD1; ZNF813; NR2C1; MED4; NR1D2; SMAD2; NFYB; NR1H3; NFKB2; RAN; IRF1; PLAG1; AHR; ZNF12; REST; ZNF148; ZNF217; ZNF623; HES1; ZNF423; MDM2; ELF2; TRIM29; ZBTB1; MAML1; TLE1; ACTL6A; NUP62; TAF9; PSIP1; ZNF667; EED; ZBTB38; TDRD3; SUPT7L; BCL6; STAT4; KDM5D; PCBD1; TP63; HIF1A; MEOX1; ZNF267; ZNF160; ITGB3BP; NFE2L1; HOXB13; GMEB1; PMS1; ZBTB11; EHF; ZNF652; ZNF721; TOPORS; ZNF432; LDB1; WT1; KLF5; ZBED2; ING2; C1D; BCOR; CTBP2; CDC5L; TFCP2L1; RYBP; ZMYM2; GTF2IRD1; HMGB2; SFPQ; ZNF419; RNF138; ZNF84; CDK8; BRCA1; BAZ2A; HMGN3; NR4A1; CREB3; IRF3; ZNF587; ZNF274; HDAC6; ARID5A; ZNF611; TTF2; HMG20A; IKBKAP; DNAJC2; CCNT1; ELF4; TAF7; HDAC9; WWTR1; TMF1; FOXN3; ERBB4; MNT; TERF1; NRBF2; TSG101; BNC1; UBP1; MED13; FOSL2; ZBTB20; RFX7; TOX; GTF3A; PKNOX1; MBD2; E2F3; NPAS2; TLE4; ZNF83; ZNF304; ZBTB43; CERS6; ATF2; TGFB1; KLF9; ZNF131; KLF10; ZNF331; CREB5; CHD9; SMAD7; HOXA10; TCEA1; ZNF443; JUP; MECOM; TCF12; YEATS4; MED14; SUPT3H; BASP1; UBE2B; TAF10; ZEB2; RAD21; GMNN; SMAD4; PLAGL2; ERBB2; NR4A2; ZNF3; TULP3; WWP1; FUBP1; GTF2I; NCOA2; ETS1; ZNF264; CTR9; DACH1; BIRC2; BMI1; SMARCD3; CRK; FOXJ3; MYBL1; NFIB; ZNF146; ELF3; LEF1; LMCD1; ZFPM2; BAZ1A; IRF7; BAZ2B; SMAD3; SNAI2; GLI2; NANOG; MNAT1; RORA; POU4F1; TRIB3; MEIS1; THAP11; FOSB; NR2F6; ZMIZ1
Down-regulation	234	TTF1; SLC2A4RG; SREBF2; HCFC1; PRPF6; SOX4; HEY2; POU2F2; GATAD2A; RHOA; PITX1; NFKBIA; PARP1; ZNF35; ID1; GMEB2; HMGXB3; RBM39; ZNF668; FOXO3; CEBPB; TP53; ZNF227; MED16; TLX1; FOSL1; ZSCAN32; CXXC1; ZNF444; NSD1; SMARCA1; NOC2L; MED25; ZSCAN2; CNOT6; CREBZF; PDLIM1; MXI1; MSX1; ZEB1; RING1; SALL1; ESR1; PAX8; WNT4; CARHSP1; ZNF335; KLF7; SAFB; RUVBL2; E4F1; TCEB2; KMT2B; ZFHX2; FOXM1; AIRE; BRF2; POU2AF1; MKL2; FLNA; HOXB5; CTCF; PFDN5; MLXIP; MTA1; ZNF770; MYOG; ABL1; VSX1; MAFG; KDM2A; LHX6; MYBBP1A; MMS19; CCNE1; ZNF10; JUND; KAT6B; NKX2-2; CHAF1B; ERCC2; YY1; ABT1; TBX3; SF1; ZNF253; STAT6; TCF4; RNF141; UIMC1; TCF25; PBX2; PTRF; TFDP2; ZBTB40; TBX2; MAFB; PRDM10; ZNF219; ZNF671; RREB1; ZNF205; MKL1; NFX1; SSRP1; ZNF516; PAX6; HMX1; ZNF211; ZNF93; PROP1; NFKBIB; ZNF586; EP400; RFXANK; HOXC4; GATA4; ZNF768; CD3D; ZNF212; HOXB2; SHOX2; TBP; SATB2; KLF6; MED24; ARNTL2; ATOH1; RELB; ID2; HHEX; ELK1; GABPA; MYBL2; BHLHE40; POLR2A; MED27; PIAS4; PMF1; SIRT7; FOXL2; RXRG; ZFP36L1; KLF12; TEAD3; RERE; GFI1; PAXBP1; KDM5B; TAL1; MYRF; NEDD8; DLX5; ZNF426; SUPT4H1; TULP4; NCOR2; FOXJ1; PCGF2; IRF4; EPAS1; FOXF1; FOS; ZNF646; FOXO1; HIRA; ELF1; DNAJC1; CEBPD; SUB1; TCF20; SP140L; HOXB6; CUX1; ZNF500; STAT5A; HDAC4; PSMC3IP; CDK2; AATF; TGFB1I1; NR2F1; RBPJ; AFF1; EZH1; ZNF165; EDF1; DLX2; JAK2; TCF15; NFE2; FOXO4; SP110; UBE2I; HOXA11; TRAK1; MAFF; TCF7L2; ID3; PURA; SMAD6; ZMIZ2; CALR; TFCP2; ZFP36L2; PSMC3; PBX3; CCNA2; HDGF; MAF; KLF2; TRIM28; TCERG1; RBBP4; ZNF467; TCF7; MYB; CREG1; DNMT1; SMAD1; TSC22D2; MED6; MED1; ZSCAN31; NKX2-1; TRIP6; HOXC6; BCL11B; TXNIP; ID4; SALL2; TRPS1; EGR1; STAT3