Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID77059	Naltrexone	GSE92742	NKDBA	Human	24h	3.3333uM	EID0445

Response Information :

Types	Number	Response transcription factors
Up-regulation	214	ID2; GATA2; IKBKAP; ZNF329; EGR3; TRIM22; ING2; SMAD7; EGR2; ZZZ3; RAN; TLE4; BBX; SAP30; SIX1; RBPMS; ZNF189; THAP10; CREBL2; ZSCAN18; NRIP1; NKX3-1; CREB3; ZEB2; PHF20; NFYB; ATF4; ATF1; RNF6; NPM1; USP22; ITGB3BP; ZNF124; STAT1; ZNF267; C1D; TSC22D3; IRF8; CBX7; CBX3; EED; CRY1; ZNF84; MTDH; TAF9; PCBD1; HIC2; ZBTB1; SFPQ; PAWR; RBBP8; NUP62; ZBTB24; YBX2; PLAGL1; TLE1; FOXA1; RNF111; HIF1A; NR4A1; IL16; ZMYM2; ZBED1; DEK; PSIP1; TEAD1; NR2C1; BRCA1; ZBTB11; ZNF274; REPIN1; HDAC6; MED4; SAFB2; HIRA; ELF2; TRIM24; PAX5; ZNF432; NR1D2; BHLHE41; SMAD2; KLF2; MNT; ZBTB25; NR1H3; RNF138; THAP1; CREB5; SKI; BCL10; ENY2; MEN1; EGR4; ZNF184; ZNF623; LMCD1; FOXJ3; ZBTB38; CHD1; ZNF143; MAGED1; MED7; ATF2; REST; TERF2; SAP18; LEF1; PIAS2; HMG20A; NR1H2; MAX; TCEA1; TMF1; HOXA10; RORA; PKNOX1; WWP1; ZNF226; ZNF146; UBP1; BLZF1; BIRC2; EHF; OSR2; CREB3L1; EWSR1; CDK8; CDC5L; TAF11; RRN3; UBE2B; NFIB; KLF4; ARID5A; DNAJC2; ZNF587; CCDC59; TERF1; CBX5; HMGN3; ARNTL; ZHX2; NCOR1; TADA3; TFAM; CHD9; NRBF2; CTBP2; CBFA2T3; NR3C2; NFAT5; ADNP; CTR9; ERBB2; DNMT3B; HLF; SREBF1; CERS6; TRIP6; ASCL1; CRK; GTF3A; ZNF160; HOXD1; ZNF140; HTATIP2; PHF8; MEF2A; BASP1; HMBOX1; NCOA2; MED23; ZNF589; RAD21; AHR; MEOX2; KLF10; HMGB2; BAZ1B; GTF2IRD1; TBX3; TOX3; ZNF721; ZBTB20; TAF10; NANOG; TFEC; MNAT1; DMTF1; DNMT1; HOXB13; GATA6; SNAI2; FOXO1; RYBP; XBP1; GLI2; CCNC; YBX1; ETS2; SMAD3; NPAS2; ZBED2; HOXC10; ZNF3; TBL1X; ZMYND8; HOXB7; MYC; ZBTB18; NR2F6; FOSB; TRIB3
Down-regulation	219	EYA2; PRPF6; MXI1; TFDP1; PAX8; POU2F2; ZNF580; ZNF444; SLC2A4RG; TCEB2; SOX4; RFXANK; GMEB2; SREBF2; FOXM1; HMX1; RHOA; ZSCAN32; LOXL2; TRIM25; FOXA2; PRDM13; PDLIM1; TLX1; ASH1L; FOXO3; MDFI; CHD7; MED25; CUX2; ZNF324B; HEYL; ZNF205; TTF1; PROP1; CALR; PHOX2B; ING4; DLX4; PITX1; SP1; ZNF668; PBX2; SNAI1; RBM39; FOXD1; NHLH1; ZFHX2; TONSL; NFE2; NFKBIA; NOC2L; ALX1; ESRRG; DCC; ZNF133; VSX1; MKL2; CEBPE; HOXA5; EVX1; KMT2B; CSDE1; NR1I3; PFDN5; LHX6; TBP; ZNF212; HOXA4; ZNF282; ERCC2; REL; CNOT6; SATB2; EPAS1; WDR77; MYOG; HOXC4; E2F4; RNF141; E4F1; MMS19; ZNF93; ZNF671; MTA1; FOXK2; SSBP3; ABL1; GFI1; PHOX2A; FLNA; VGLL4; SAFB; ATN1; NAB2; ID1; DRAP1; CEBPD; SALL1; KLF12; SIRT7; PAX6; HAND1; HLX; NKX3-2; ZNF646; NEUROD6; TP53; EYA1; ZNF768; RING1; TBX2; ZNF787; HHEX; CARHSP1; SRCAP; VEZF1; ZFY; HIPK2; NRF1; FOXJ1; SUPT4H1; PA2G4; ZNF629; PEX2; HEY2; CNOT3; MECOM; NEUROD1; ZMYND11; ZIC1; PSMC3; SUB1; NFE2L2; DBP; TAF4; RARA; ZNF200; WHSC1; ARRB1; FOSL1; TCF15; CCNE1; SFMBT1; BRF2; NKX2-1; YBX3; NFATC4; FOXF1; FOXF2; MSX1; BRD2; HBP1; MED1; ZNF91; CD3D; BHLHE40; ESR1; AATF; MAZ; ZNF426; GLI3; ZNF43; PBX3; NCOA1; ZNF219; CHD8; KLF7; BARX1; ZNF688; NCOA6; OLIG2; TFCP2; VPS72; ELF3; SMARCB1; HDGF; BCL3; POLR3C; ZFP36L2; KDM5C; ZNF22; NFKBIB; STAT5A; HOXB5; GCFC2; DLX5; HEY1; TFAP2A; ZFHX4; NAB1; FOXE1; ZNF467; HOXA11; CREG1; MED13; ZEB1; TAF1D; TAF9B; MLXIP; RUNX1; ARNT2; CTNNB1; ARID1A; PCGF2; TCERG1; BCL11A; SOX11; DLX2; MAFF; AFF1; ELF1; ZNF232; ID4; SOX9; IRF6; KDM5D; MEIS2; EGR1