Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID77058	Naltrexone	GSE92742	NKDBA	Human	24h	10uM	EID0445

Response Information :

Types	Number	Response transcription factors
Up-regulation	214	STAT1; IKBKAP; SMAD7; TRIM22; NKX3-1; MTDH; SIX1; HOXA7; RFX7; ZNF329; BBX; CRY1; RBBP8; HCFC2; NRIP1; AHR; C1D; HES1; TDRD3; CBX3; MED4; NR2F2; PHF20; PMS1; ATF1; SATB1; RNF138; RBL2; RRN3; THAP1; USP22; DEK; ING2; CREB5; MDM4; CREB3; BCL10; BNC1; TAF9; NFE2L1; CREBL2; PCBD1; PSIP1; RBPMS; ZNF460; ZNF468; TCF12; TSC22D3; TEAD1; ZBTB11; ZNF813; ZNF432; TLE4; ZZZ3; ZBED1; ATF2; YEATS4; TERF2; WDHD1; REST; ACTL6A; SMAD5; RNF6; VAX2; TTF2; SAP30; PAX5; TFAM; ZNF217; NR4A1; ZSCAN12; MAML1; HOXD1; TCF3; ELF2; HIF1A; PIAS2; FOXA1; ZMYM2; TLE1; PHF2; NCOR1; MED14; MNT; GFI1B; HMG20A; SOX15; CDK8; HOXC10; ZSCAN18; MED7; ZNF623; HMGN3; NUP62; HDAC6; E2F3; EGR2; SFPQ; EED; BRCA1; FOXN2; PRKDC; THAP10; GTF2I; PLAG1; BCOR; ZBED4; MDM2; EGR3; MEOX2; AES; ARL2BP; ITGB3BP; ZFX; HMGB1; CHD1; BCL6; IRF2; SMAD2; TAF11; TCEA1; BRIP1; TAF7; HOXA10; HMBOX1; LEF1; CHD9; CDK7; BIRC2; UTF1; NR1H2; ARID5A; PRMT2; NFAT5; TP63; TMF1; ZBED2; KLF2; KLF5; TOPORS; BPTF; IFI16; KLF10; E2F5; NR2C1; SAP18; BAZ1B; SKIL; NR1D2; REPIN1; DNAJC2; DMTF1; MAGED1; NFIB; KDM5D; ZNF146; APEX1; UBP1; ERBB4; TOX; RAD21; RB1; UBE2B; CCDC59; TERF1; AEBP1; IRF8; ZNF267; IRF9; PLAGL1; ZNF12; ZFP69B; EWSR1; SIX2; GTF2IRD1; KAT6A; MTF2; ZNF226; HSF2; ETS2; SETD2; MBD2; NR3C2; NFIC; HOXB13; TAF5L; ZEB2; KLF13; ZNF131; GLI2; ASCL1; WWP1; CRK; CBFB; DNMT1; ARNTL; TRIM32; GTF3A; POU4F1; RORA; AGO2; HDAC2; SP3; MNAT1; FOXJ3; TGFB1; FOXG1; OSR2; ISL1; TRIB3; ZNF532; XBP1; CEBPZ; TXNIP
Down-regulation	248	PRPF6; TFDP1; TP53; SMARCA1; FOSL1; PAX8; PITX1; PBX2; MAFG; TFDP2; ZNF93; SIRT7; FOXO3; GMEB2; MXI1; PDLIM1; ERCC2; SLC2A4RG; CARHSP1; KMT2B; ZSCAN32; RHOA; ID1; SREBF2; RBM39; ZNF133; RFXANK; RERE; MYOD1; EVX1; ZNF768; MYOG; ZNF212; HOXC5; HMX1; ZEB1; ZFHX2; ZNF224; BTG1; BTAF1; ZNF426; ZNF302; MTF1; DLX4; NOC2L; GATA4; MED16; ZNF91; PROP1; NFKBIA; ZNF35; FOXM1; CHD7; NFE2L3; POU6F1; TRIM25; FLNA; POU2F2; NHLH1; MSX1; ZNF671; HHEX; GATAD2A; GABPB1; ZNF253; NFE2; CDX1; MNDA; ATN1; E4F1; TBX2; ZNF43; NKX2-5; MMS19; CHAF1B; CXXC1; PFDN5; ZNF219; ZNF580; HEY2; MYBL2; NCOA1; ALX1; CITED2; HOXC4; ZNF205; ING4; EDF1; STAT5A; ARID3A; NKX3-2; CALR; BRD2; SOX4; IRF1; NAB2; E2F8; PHF1; NFATC1; ZBTB48; ZNF335; REL; HCFC1; ZNF266; ZNF665; MED25; CEBPE; ZNF629; MAFB; ZNF500; ZBTB17; SIM2; ZIC1; ZNF264; ID4; LHX6; FEV; DAXX; ERF; PHIP; ABL1; FOS; FOXL2; TBP; GFI1; DBP; LIN28A; PTRF; ZNF211; TCF20; ZNF586; ZBTB20; BATF; FOXA2; HSF4; CNOT6; HIPK2; RXRG; TCEB2; YBX3; KAT6B; TEAD3; HBP1; MTA1; ZFHX4; PSMC3; HDAC7; PAXBP1; PAX6; CREBZF; TCF15; SALL1; KDM5B; ZNF274; TAF1D; ZNF430; PA2G4; KLF6; FOXJ1; USP16; SMARCB1; ZNF688; NRF1; DDX17; NFE2L2; ZNF672; ZNF652; MLXIP; RELB; EPAS1; MZF1; LHX3; CEBPD; ELK1; HSF1; MYRF; RXRA; ENO1; CTNNB1; AFF1; ZSCAN31; PEX2; RORC; CIC; SSBP3; ATF7IP; EYA2; KDM5C; NFKBIB; SFMBT1; WNT4; NFATC4; TSC22D2; EMX2; ELF3; CD3D; FOXD1; MECOM; HAND1; HLX; PHOX2B; CNOT3; ZNF394; HLTF; ESR1; ZNF711; HOXB5; TRAK1; DNAJC1; HOXB2; CENPB; IRF4; TWIST1; JAK2; MAF; NFIL3; NELFB; MLXIPL; PCGF3; CBX4; ELF5; TOX3; FOXF1; NCOA4; ZKSCAN1; FOXF2; RFX5; MAFF; ZNF281; BCL3; CCNA2; TCF4; NAB1; NR2F6; PBX3; BCL11A; HOXC6; ZMYND8; POU2AF1; HMGA1; HOXB7; IRF6; TBL1XR1; STAT3; TRPS1; PEG3; SOX9; EGR1