Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID77045	Pyrvinium-pamoate	GSE92742	NKDBA	Human	24h	1.1111uM	EID0445

Response Information :

Types	Number	Response transcription factors
Up-regulation	260	ID2; EGR3; SMAD7; IKBKAP; TAF9; THAP10; BBX; TRIM22; MTDH; CARF; CHD1; EGR2; ST18; ZNF468; MYT1L; ZNF83; BCL10; ZNF667; ZNF177; ZNF329; BHLHE41; TERF2; PMS1; AES; CRY1; SIX1; PAX5; ATF4; CAPN15; CREBL2; ZBED2; ZEB2; STAT1; ZNF268; UBE2B; ZNF460; ZNF623; HOXD1; NR1D2; CREB3; ZNF131; MTF1; CHD9; ZNF189; TLE2; NR2C1; ZNF12; RNF6; THAP4; PAX6; MEOX2; ZNF529; CERS6; DDIT3; NFATC3; REPIN1; ZNF813; SUPT7L; ZNF304; ZNF112; ATF2; CREB5; DEK; ZMYM2; RB1; ZNF536; ERBB4; THRA; ZSCAN12; BAZ2A; FEZF2; ATF1; RBL2; PHF20; CCDC59; ZNF141; ARID5A; ZNF778; ZNF267; OVOL2; HOXA7; USP22; NRIP1; INSR; EN1; IL16; ZNF175; ZNF146; NPAS2; RAD21; ZNF24; ZNF551; INSM1; SUPT3H; NR4A1; SPEN; ZNF432; JUNB; HIF1A; ZNF23; MYT1; NR2E1; EGR4; TGFB1; RNF138; HOXA1; ZBTB11; NFAT5; MED14; THAP1; TSC22D3; TCF12; RFX7; MEN1; RRN3; ZBTB18; NR1H2; FOXN2; CCNC; RBBP8; ZNF160; DACH1; MAML1; FOSL2; AEBP1; MLLT10; ZNF573; PCBD1; ARID4B; CDK8; FOXA1; TLE1; C1D; ZNF692; ZNF124; BLZF1; ZNF264; PAWR; ARNTL; RBFOX2; FOXG1; ZZZ3; SPDEF; ZIC3; ZNF415; DMTF1; IRF8; HES1; EHF; HOXB13; CBX5; IRF1; ZBTB24; MNDA; KAT8; TMF1; TCEA1; EGR1; SERTAD2; GTF2IRD1; CTBP2; ZNF587; ZNF574; HEY1; CRK; CBX3; L3MBTL1; ZNF117; KLF13; TOPORS; ADNP2; ZBED4; ZFP69B; GLI2; BRIP1; SIX3; CDC5L; FOXE1; ENY2; COPS2; TFAM; KLF10; BCL6; PSIP1; CUX2; HMGA2; NHLH2; ASCL1; TP63; WWP1; HMGN3; CBX7; MBD2; ZNF552; MEF2A; CBX6; BCLAF1; NLK; ETS1; ZNF107; SKIL; CDK9; PLAGL1; MXD1; TAF10; ATF3; ZNF165; TAF7; TRIM29; MDM2; CEBPG; BIRC2; AHR; TOB1; WNT4; TRIB3; FOSB; FOXJ3; BNC1; TFEC; EWSR1; BMI1; SMAD4; MED23; ERG; NKX2-2; TOX; CNBP; TERF1; ELF5; TRPS1; ZNF721; XBP1; HOXA10; ZHX2; LEF1; POU2AF1; HDAC2; USF2; PPARG; HDAC9; THAP11; PRRX1; MYRF; ISL1; ETV5; ZKSCAN1; HOXB7; IRX5; PATZ1; DNMT1; BAZ2B; SP3; NR2F6; MYB; NKX2-1; TOX3; TBL1X; HOXC6; SNAI2
Down-regulation	283	LOXL2; TFDP1; PAX8; FOXM1; EZH2; SMARCA1; CENPF; RERE; SOX4; CARHSP1; NFE2L3; RHOA; HMGB3; SREBF2; RBL1; PRPF6; TTF1; NFKBIA; FLNA; SIRT7; ZSCAN32; HMX1; EVX1; FOXO3; VGLL4; ASH1L; SUV39H1; ABL1; JUND; PDLIM1; TLX1; ING4; PTTG1; ERCC2; CCNE1; AR; KLF6; CRTC1; AIP; WHSC1; HEYL; NFE2; HMGXB3; PBX2; HEY2; ZNF227; TBP; ZKSCAN3; DRAP1; HCFC1; RXRA; ZNF239; ZBTB7B; ZNF324B; FOXF1; SLC2A4RG; HOXC4; KLF15; ENO1; MYBL2; ZNF32; SNIP1; TCEB2; RNF141; TAF12; LIMD1; PARP1; CNOT6; RCOR1; ZFHX2; POLR2A; POU2F2; ZNF671; ZNF444; CDK2; KAT5; MXD3; MAFG; ALX1; PCGF2; KDM2A; ZNF212; HHEX; ARRB1; THRB; ZNF771; SALL1; PSPC1; NFIX; LPIN2; SETD3; ZNF93; ZNF35; TAF4; BRF2; PEX2; HOXD9; SSBP2; GABPB1; MEIS1; HOXC5; WDR77; NR2F2; SATB1; ZBTB14; SFMBT1; EHMT2; HINFP; E2F8; PUF60; HOXD11; NOC2L; MAP3K10; KMT2B; KDM4C; KLF12; PSMC3; TRIM24; CREBZF; TBX2; ZNF335; NR1I3; PFDN5; SUPT4H1; URI1; NR0B2; SSRP1; TCF15; TEAD3; FOXL2; HLF; HOXA11; ZNF43; BATF3; EPAS1; BRD3; FOXD1; TFCP2; ZNF384; MYCBP; BRD2; MXD4; ELK1; NCOA1; FOXO4; BCL3; SMARCD1; ELF1; DDX5; ZNF516; PHF1; BRD8; ELK4; NKX3-2; RBPJ; NFKBIB; RBBP4; HDAC3; THRAP3; NFX1; SUB1; TFDP2; ZNF544; EP400; ZNF350; CTNNB1; PITX1; MECOM; BRPF1; NRF1; PROP1; CIC; RFXANK; ZMIZ2; RBBP5; PRDM10; NFYC; TRIM27; FOXJ1; HAND1; SMARCA4; SOX12; ZNF266; SSBP3; DAXX; CREB3L1; KDM5B; YAF2; HBP1; NKX3-1; ZNF226; AFF1; EDF1; ZNF274; RORC; ID1; AATF; STAT2; SOX11; ASH2L; PMF1; HDAC7; LITAF; ZFHX4; SMAD6; PRDM1; SP110; KAT7; MYCN; MXI1; MSC; ARID5B; TRIM16; NEDD8; MEF2C; BHLHE40; TCERG1; DDX17; RBM39; GCFC2; NFATC1; MED1; NFRKB; JARID2; NFIL3; VEZF1; ELF3; CREG1; FLI1; DNAJC1; SETDB1; YAP1; HDGF; HMGB2; JAK2; MAFB; ZSCAN31; HTATIP2; PPARGC1A; ZFP36L2; PKNOX2; EMX2; ZNF219; RFX5; HMG20B; FOXN3; HLTF; NAB2; IRF9; HDAC1; ID4; JUP; STAT5A; UIMC1; CITED2; YWHAB; PBX3; PQBP1; HOXB2; CALR; TCF21; PBXIP1; NR0B1; TRIM32; SIAH2; YBX3; TBPL1; TXNIP; KLF11; WT1; ZBTB20; EYA1; MED6; ZNF532; KAT2B; KDM5D; MAF; MITF; TSC22D2; BTG1; PIR; STAT3; SMAD3