Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID77044	Pyrvinium-pamoate	GSE92742	NKDBA	Human	24h	3.3333uM	EID0445

Response Information :

Types	Number	Response transcription factors
Up-regulation	233	TRIM22; IKBKAP; PHF20; ZEB2; SAP30; SMAD7; FOSL2; SUPT7L; BBX; ATF4; NR1D2; HCFC2; MTDH; CREB3; MAML1; NRBF2; ATF1; ZZZ3; RNF111; NR2C1; NRIP1; THAP10; MDM2; TCF12; SMARCA2; RNF6; ARNTL2; SATB1; ANKRD1; CRY1; TAF9; EGR2; TFAM; ATF2; STAT1; PMS1; EED; NFAT5; NR3C1; RB1; USP22; ZMYM2; IKZF5; SREBF1; ZBTB38; CHD1; C1D; CTR9; UBE2B; BCL10; DMTF1; TLE1; ZNF529; ST18; HIPK1; TERF2; ZBTB11; NUP62; HDAC6; TSC22D3; TDRD3; RBL2; THAP1; CREBL2; HOXA7; CREB5; NFE2L1; REPIN1; GTF2IRD1; DEK; NKX3-1; MED4; RFX7; MNT; DDIT3; ZNF189; RNF10; AHR; EGR3; ZNF468; COPS2; HOXD1; ZNF536; IRF8; CBX3; HIF1A; TOB1; ATF3; ZNF23; ZBTB1; SMAD5; BMI1; BPTF; ZFX; ADNP; ETV5; TOPORS; ZKSCAN1; MEN1; ZNF202; HMGA2; NFYB; KAT8; ZBTB25; ZNF813; SIX1; TP63; BIRC2; ARID5A; MLX; CHD9; CRK; UBP1; PBRM1; SMAD2; ZNF692; ZFP30; PSIP1; PLAG1; SETD2; TRIM16; KLF9; ELF2; PIAS2; FOXJ3; CCNH; ZBTB18; RELA; LPIN2; XBP1; SP100; TRIM29; BHLHE41; ZNF432; HOXA10; AES; REST; PHF2; MGA; HMGN3; MED7; TGFB1; ZBTB16; PLAGL1; CERS6; RNF138; ITGB3BP; RBBP8; CCDC59; TAF7; MAX; RORA; ZNF148; MEF2A; NCOR1; IRF7; NFIB; HOXC10; ZNF24; BAZ1B; HOXD3; ZBTB43; TULP4; NPAS2; BCL6; NAB1; BACH1; BASP1; TAF6; JUNB; ZFP64; PHF8; MYRF; BNC1; GTF3A; ZNF131; PPARG; WWP1; TCEA1; TRIM32; SMAD4; PURA; TRIB3; MED13; HDAC9; CTBP1; DNAJC2; ZNF146; TRIP6; HMG20A; ELK3; ZBED4; CEBPG; HSF2; SNAI2; CTBP2; PPP1R13L; SPDEF; LEF1; VDR; PATZ1; HIVEP1; ARID5B; DPF2; PAX5; TOX3; SP3; NHLH2; TSC22D1; GTF2I; MNAT1; RARA; SMAD3; MYC; ETS2; MITF; ZNF281; VGLL4; KLF13; ZNF12; WWC1; JUP; SERTAD2; BAZ2B; KAT2B; TGIF1; ZNF532; THAP11; FHL2; ZIC1; DNMT1; SCAND1; ZMIZ1
Down-regulation	243	FOXM1; LOXL2; PARP1; HMGB3; CENPF; ZNF544; PITX1; CCNA2; MXD3; ZNF93; ID4; E2F8; ID3; TFDP2; NOC2L; CCNE1; HHEX; KLF6; CEBPD; ASH1L; ID1; SLC2A4RG; RXRG; EZH2; FOXL2; TFDP1; EVX1; JUND; PAX8; CARHSP1; E4F1; GATAD2A; RHOA; TOX4; RERE; HEY2; NKX3-2; RFXANK; ZNF239; RUVBL1; SREBF2; HMX1; ZKSCAN3; ZNF671; THRB; LIN28A; GATA4; ZNF444; HIC2; KMT2B; SSRP1; HMGB2; PBX2; MYBL2; HCFC1; ZNF350; NFKBIA; HMGB1; PRPF6; NR1H4; PAX1; ZNF43; HIPK2; FOXF1; TFAP2A; CHD8; E2F4; CD3D; ABL1; UBE2L3; ZNF787; PTTG1; EYA2; ZNF324B; ZNF75D; PRDM10; HLF; ZNF253; ZSCAN2; NFE2L3; ZNF133; ZNF219; CDX1; HOXC8; NFYA; NFE2; TP53; ZKSCAN4; SOX21; SALL1; TAF9B; ERCC2; HOXC4; ZFHX2; ZNF91; WNT4; HIRA; TCF7L2; ZBTB20; PSMC3; CTCF; ARRB1; ESR1; ZNF180; SOX17; HMG20B; ZNF768; E2F2; CHAF1B; NAB2; ZNF85; ZNF205; ZNF250; AR; RORC; WWTR1; PA2G4; GMEB2; MLXIP; BRWD1; GATA1; HOXC5; SOX4; PPRC1; ZNF10; RNF141; ZNF212; MAZ; SAFB; CDK2; ZBTB48; NHLH1; TCEB2; FEV; PTRF; TRIM27; CEBPE; ZSCAN31; ING4; TCF3; ZBTB17; SMAD1; FLNA; DDX17; CALR; ZNF701; MED20; PRDM14; HOXB5; KLF7; ZNF516; HDGF; PFDN5; TEAD3; TCF21; ZNF586; NEDD8; SRF; ARID3B; ZNF165; SMARCB1; ZNF211; FOXF2; SSBP3; ZHX2; LHX3; BNC2; PIAS4; NRF1; BARX1; GFI1; BRF2; ZNF611; SIRT7; ZNF500; PHOX2B; PKNOX2; ZFHX4; SPIB; NANOG; FOXD1; NR2F1; POLR3C; HOXA11; AEBP1; EPAS1; ENO1; SOX13; DNMT3B; LYL1; ZSCAN16; ATOH1; ZNF589; ZNF117; TGFB1I1; PBXIP1; MEIS2; ZNF711; BTAF1; ARNT2; TWIST1; PPARGC1A; SUB1; ZNF512B; POU5F1B; PBX3; SOX11; ISL1; ALX1; EMX2; TULP3; CITED1; ELF3; MSX1; PCGF3; TFAP2C; SUV39H1; BCL3; BCL11A; MYCN; SOX2; MAFB; NFIL3; IRF6; NR2F6; SALL2; ZEB1; FOXO1; MYBL1; TFEC; TCF4; GRHL2; CITED2; NR0B1; CREB3L2; DLX2; MEIS1; NKX2-1; CTNNB1; HMGA1; AFF1; TXNIP; EGR1