Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID77039	Vorinostat	GSE92742	NKDBA	Human	24h	10uM	EID0445

Response Information :

Types	Number	Response transcription factors
Up-regulation	117	SIX1; EGR3; ATF3; E2F5; TCFL5; NR4A1; IKBKAP; NR4A2; SUMO1; HOXA5; CREM; FOXA1; BBX; TDRD3; ZNF331; WT1; NR5A2; TAF11; TAF10; ZNF667; RBBP5; EGR2; HEY1; L3MBTL1; AES; HOXD1; SMARCD3; STAT1; TBX1; MTF2; TLE2; MEOX1; ADRB2; NR2F1; CREB3; ENY2; HDAC5; CREBL2; CHD1; UBE2B; RXRB; RUNX3; ERBB4; INSR; TGFB1; CTR9; MED21; JUNB; EGR4; NRBF2; TEAD1; PBX1; CBX6; ITGB3BP; TSG101; SND1; INSM1; CDYL; NR4A3; ZBED2; HSBP1; CBX4; MTDH; HES1; CRY1; RARA; IRF4; ZBTB11; NR3C2; TERF1; HMG20B; BRD4; ZNF589; BAZ2A; SIN3B; PEG3; WWP1; MYCL; ZNF721; ZNF160; WWC1; SPIB; TSC22D3; MYCBP; ZNF281; CCNC; ECD; MXI1; RCOR1; ZNF12; PITX1; CUX1; SMAD7; HMBOX1; CRK; JARID2; MEIS1; SALL2; SOX3; GLI2; CTBP2; ID3; TLE1; FOXO1; HIF1A; DACH1; NKX2-2; MYC; NFIB; LEF1; THAP11; BASP1; TSC22D1; FOSB; SMAD3; NR2F6; TRIB3
Down-regulation	165	TP53; FOSL1; FOXM1; WHSC1; PAX8; FOXD1; ATF5; ABL1; HMGB1; NFKBIA; TGFB1I1; HIRA; CHAF1B; SUV39H1; KDM5D; ZNF282; PMF1; SCMH1; VGLL4; TLX1; TFDP1; CENPF; TTF1; NFE2L3; SLC2A4RG; FEV; CTCF; SALL1; ZBTB14; KLF7; CEBPD; SP140L; KLF6; PRPF6; RBM39; STAT6; HMGB2; ID1; PUF60; EYA2; ZNF544; SMARCA2; ZNF264; SFMBT1; SIAH2; PTRF; CARHSP1; GMEB2; ELF1; HOXC4; MSC; CBX5; HCFC1; HMX1; HMGA1; ARL2BP; KLF11; FHL2; ESR1; ETV6; CEBPG; ELF3; MTA1; CREB3L1; HOXC8; BARX2; GABPB1; ZHX2; CCNA2; NFE2L2; NCOA6; ENO1; NFKB1; TGIF1; FOXO3; HAND1; PHOX2A; FOXA2; ZFP36L2; PTTG1; DDX17; NKX3-1; KDM4C; YBX3; HMGB3; ZNF136; CSDE1; EN1; HMGXB4; NCOR1; YEATS2; PHOX2B; BACH1; BCL11A; CTNNB1; HNRNPD; RUNX1; MNDA; BCLAF1; KMT2B; IFI16; ZNF430; ELF5; HOXC10; STAT5A; DDIT3; HHEX; MYCN; MYB; ZNF22; PRMT2; TFCP2; SMARCC1; POU5F1B; TRIM28; NR2F2; ZNF93; RBPMS; HOXA11; MSX1; ZNF43; RBBP4; SP3; ZEB1; BAZ1A; GFI1; ZBTB16; ZMIZ2; FOXF1; TCERG1; MED24; KLF5; MED1; TRIM22; SP110; HOXC6; LMCD1; KAT7; MAFB; TRIP6; SOX17; ST18; MAFF; PCGF2; TBL1XR1; NFIL3; PSMC3; SOX9; CEBPZ; ETS2; MAGED1; PHIP; ZNF532; NAB1; HTATIP2; TXNIP; ZBTB38; AEBP1; PIR; TBL1X; HOXB7; ERBB2; DNMT1; DLX5; EGR1