Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID77038	Pevonedistat	GSE92742	NKDBA	Human	24h	0.4111uM	EID0445

Response Information :

Types	Number	Response transcription factors
Up-regulation	223	EGR2; EGR3; SATB1; IKBKAP; MTDH; IL16; SIX1; DEK; RAN; PAWR; SAP30; FOXA1; ING2; ATF3; CREBL2; CDC5L; TAF9; DR1; MNDA; NR4A1; PHF20; NKX3-1; PRDM4; C1D; RBBP8; HOXC13; ZNF665; BBX; CLOCK; IKZF1; PPARD; ZBTB11; SRF; OVOL2; ZNF778; ZNF611; ZNF354A; ZBTB1; SUMO1; ZBED1; CTBP2; ZZZ3; ZNF415; ZNF239; BCL10; ZBED2; RARG; PLAG1; MEOX1; GATA6; BACH1; HOXD1; BANP; KLF10; TAF11; SSX1; TDRD3; SPDEF; SNAPC4; ZNF83; CERS6; CCDC59; NUP62; ZNF652; COPS2; ZNF248; IRF7; ZNF692; NR1H3; BRCA1; EGR1; ARNTL; TRIM22; FUBP1; MED20; ZNF160; CBX6; MTF2; RNF138; PCBD1; FOXO1; EED; DNAJC2; TLE4; CBX3; E2F3; NFYB; RBFOX2; WWP1; ZNF721; PRRX2; ZNF33B; TCF7L2; PSIP1; CRY1; SOX11; ERBB4; BLZF1; ETS1; CHD1; CREB3; ZNF552; MED4; SHOX2; SIX3; TFEC; NFATC3; TFCP2L1; TEAD1; HIF1A; YBX2; PLAGL2; TFAP2C; CCNC; RNF6; THAP1; KLF13; ZNF12; TAF5; TSC22D3; NFAT5; KLF9; PHIP; CUX1; HOXC11; TTF2; TFAM; ZNF146; ITGB3BP; TCF7L1; ETS2; GLI2; SFPQ; MNT; ENY2; RBPMS; INSR; WDHD1; ZBED4; ZNF44; NR1H2; SMAD2; RRN3; ZNF165; KLF4; ADNP; ZNF131; ELF4; MYC; TLE1; NCOA2; KLF11; HOXB6; CRK; BRIP1; BNC1; SOX2; MED7; RB1; EHF; MBD2; GTF2IRD1; ST18; ZNF589; BACH2; UBP1; COPS5; L3MBTL1; ATF2; BNC2; HDAC9; PAX5; ILF2; HDAC2; HMGB2; AHR; SREBF1; POLR3C; MEF2A; ZBTB16; ISL1; TERF2; FOXJ3; BCL6; DMTF1; BIRC2; LITAF; UBE2B; KAT6A; RUNX1; KDM5D; SMARCD3; GTF3A; DNMT1; RAD21; ZMYM2; GRHL2; TGFB1; NFIB; KLF5; JUP; LEF1; SMAD3; WWC1; USP22; ELF5; PEG3; CBFB; TRIB3; SPIB; NANOG; NR2F6; HOXB7; BCL11B; XBP1; HOXC10; HOXC6; FOSB; CEBPZ; THAP11; ZMIZ1; ZFPM2; PPARG
Down-regulation	201	GATAD2A; SOX4; PRPF6; SALL1; TP53; MXI1; PHF1; SLC2A4RG; FOXO3; FLNA; POLR2A; TLX1; MDFI; PBX2; PDLIM1; SUPT4H1; SMARCA2; MED16; HMGB1; ZNF205; ZSCAN32; HOXA5; RHOA; SIM1; BRD2; NFKBIA; EYA2; SMARCC2; EHMT2; SIRT7; TTF1; SATB2; ING4; MED24; MTA1; MSX1; PAX8; PFDN5; ZNF227; KMT2B; ZNF768; KAT5; ZNF580; HEY2; ABL1; FOXO4; ID1; SREBF2; ZNF22; SIX5; MED1; NCOA1; ATF7IP; POU2F2; HDAC7; FOXM1; TONSL; ZNF93; ZFHX2; HSBP1; VSX1; EMX2; JUND; CREBZF; TBX2; CXXC1; SMAD6; E2F2; ZIC1; PEX2; TCF15; ZNF646; TFCP2; TCF25; NKX2-8; ZNF274; PITX2; TBP; TBX21; ZBTB32; MEF2D; TAF12; BRD8; CEBPB; HOXA4; RUVBL2; TSC22D1; ALX1; ID2; KLF1; ID3; NFE2L2; FOS; DDX17; ZNF184; E4F1; ELF1; BHLHE40; SMARCA1; FOXF1; NONO; CIC; CEBPD; CARHSP1; TCEB2; ZHX2; PURA; RING1; TRIM25; NOC2L; OLIG2; EDF1; CIZ1; KAT7; EPAS1; HBP1; ZNF516; NFKBIB; BATF3; TSC22D4; KDM4A; ZNF350; ZMIZ2; RELA; MSC; TGFB1I1; RFXANK; ETV6; TGIF1; PAX6; RBBP4; CITED1; KDM5B; ATN1; YBX3; HDAC1; ZNF500; NRF1; KLF2; RERE; PPARGC1A; WHSC1; HOXC4; HLX; NFE2; RFX7; HOXA11; PKNOX2; SND1; KAT6B; FOXL2; ZSCAN16; BTG1; ZEB1; PCGF2; TAL1; MAF; KAT2B; BCL3; HDAC4; MAGED1; AFF1; CALR; CTNNB1; SMARCB1; DNAJC1; TAF9B; BCL11A; MED23; ZBTB38; ZNF711; TULP3; TBX3; FOXC1; PITX1; VGLL4; TCF7; UBE2I; RFX5; JAK2; EYA1; PBXIP1; TRAK1; KDM5A; SSBP3; ID4; ZXDC; HEY1; CREG1; ZEB2; BRD4; JARID2; SOX9; DLX5; NCOR2; HMG20B; HMGA1; TXNIP; MEIS2; TWIST1; STAT3