Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID77036	Pevonedistat	GSE92742	NKDBA	Human	24h	3.7uM	EID0445

Response Information :

Types	Number	Response transcription factors
Up-regulation	155	SSBP2; TRIM22; IKBKAP; SIX1; MTDH; SAP30; RAN; ING2; PPARD; MDM2; TAF9; NUP62; EGR4; PMS1; EGR2; SMAD7; CCDC59; KLF10; MDM4; HOXD1; LEF1; ZNF124; ATF3; RNF138; EGR3; RBBP8; DNAJC2; PCBD1; ZBTB24; NR2F2; MTF1; CRY1; C1D; COPS2; AHR; PHF20; NR2E1; CHD1; ZBTB11; ZNF432; NR2C1; MYT1L; UBE3A; CREB5; PSIP1; TADA3; DEK; NKRF; PLAGL1; ARID5A; HIC2; EED; NPM1; TAF11; RFX7; MEOX2; CBX5; ZNF529; HMG20A; BBX; PAX5; MYCBP; HMGN3; IRX5; HEY1; TLE1; CREB3L1; ZNF562; ZNF536; RBFOX2; MAFG; SIX3; MYC; MAZ; ELK3; MTF2; BCL10; RNF10; ZNF623; FOXN2; CASZ1; EMX2; CRK; CBX3; BRCA1; CTR9; TFAM; SHOX2; SP100; ZNF160; ZMYM2; ZNF267; NR3C2; WWP1; CCNC; PRMT2; TAF10; GLI2; ZHX3; SMAD2; ZNF721; HMBOX1; BATF3; SERTAD2; CCNT1; NHLH2; FOXJ3; KDM5D; ZNF44; SOX11; OSR2; MEF2A; PIAS2; SMARCD3; TCF7; GTF2IRD1; ATF4; HDAC2; YBX1; ZFHX4; NEDD8; CARM1; BAZ1A; FUBP1; ZNF3; MEOX1; PIR; BMI1; UBP1; NFIB; RORA; GTF3A; BCL6; ECD; HOXC10; TLE4; NR4A1; INSM1; TOX; DNMT1; BIRC2; CNOT2; KLF13; VDR; BAZ2B; JARID2; CBFB; FOXG1; RAD21; XBP1; BASP1; TRIP6; ZFPM2; CEBPZ; NR2F6
Down-regulation	170	FOXM1; RHOA; PITX1; NFE2L3; CENPF; IRF4; LOXL2; HBP1; TCEA2; PRPF6; TFDP2; PTRF; NFKBIA; KMT2B; SMARCA1; CARHSP1; RBL1; FOSL1; ID1; ABL1; ELF3; ZHX2; SOX4; CHD7; CEBPD; ATF7IP; ZNF35; TP53; RXRA; VEZF1; GMEB2; ZNF93; FLNA; SUPT4H1; HIPK2; ID4; ZNF227; BRD7; TAF9B; PAX8; CCNA2; GFI1; HEY2; ZMYND11; ID2; ZKSCAN4; ZNF45; PURA; RUNX3; SOX13; ZNF75D; TCEB2; MAFB; MXI1; BARX2; CTBP2; ZNF302; BRD8; FLI1; ZNF331; E4F1; KLF3; HHEX; EHF; ZNF768; ZBTB16; SNAI1; DDX17; DBP; NFKB1; KLF5; ZNF787; PREB; FOXF1; FOS; MNX1; SIRT7; SSBP3; NRF1; HDAC5; TAF12; PNRC1; RELB; ARNTL2; TAF5; AFF1; TBX2; FOXO3; NFX1; ZNF274; SMAD6; PPP1R13L; SOX9; TCF7L2; MLXIP; ZNF500; PPARGC1A; MYRF; KLF6; TCF25; KLF9; CNOT6; JAK2; ZNF215; ID3; DNAJC1; EPAS1; PTTG1; YAP1; LITAF; FOXL2; NAB2; SATB2; FOXO4; TBP; HOXB2; PITX2; PRDM1; SOX12; MED13; THRAP3; FOXO1; CREB3L2; CENPB; ZSCAN16; CNOT3; LIN28A; EYA2; ELF1; CALR; BCL3; SALL1; ZEB2; CCNE1; EDF1; PBX1; GATA6; NR1D2; SREBF1; KAT7; ZNF589; UBE2I; ZNF264; BTG1; FOXC1; FOXE1; TCF21; JUNB; MAF; IRF6; TSC22D1; PSMC3; RFX5; DLX5; TRIM28; BCL11A; TGIF1; AEBP1; TFAP2C; PRRX1; TXNIP; ZFP36L2; MYBL1; TOB1; WWC1; PBX3; TRPS1; NANOG; EGR1; STAT3