Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID77035	Pevonedistat	GSE92742	NKDBA	Human	24h	11.1uM	EID0445

Response Information :

Types	Number	Response transcription factors
Up-regulation	154	EGR3; EGR2; ATF3; IKBKAP; RAN; NUP62; CREB5; PLAGL1; ING2; TRIM22; MTDH; NFIB; C1D; ZNF143; TAF9; TEAD1; IRF3; NR2F2; ZNF267; PCBD1; DNAJC2; THAP10; PAWR; RNF138; BBX; PHF20; TLE4; CCNH; MTF1; PMS1; NR4A1; FOXJ3; EMX2; RBBP8; ZMYM2; COPS2; ZZZ3; ZBTB24; CCDC59; NRBF2; PSIP1; CHD1; TFAM; ELF5; SMARCD3; HLF; HOXA5; ANKRD1; EGR1; ZBED1; NFATC1; GTF3A; ZNF84; NR2C1; TLE1; REST; EGR4; ZNF721; ZNF160; CBX3; WWTR1; ZBTB11; BCL6; ZNF432; CCNC; TAF11; MDM2; HOXC10; ARID5A; KLF10; BATF3; MITF; RBBP5; MEOX1; RBPMS; PKNOX1; HOXD1; MYCBP; MYC; ZBTB38; BRCA1; FUBP1; ATF4; CBX6; STAT2; RRN3; TSG101; SIX1; SMAD2; MTF2; RORA; ZNF44; BHLHE41; CRK; ZNF165; GLI2; BAZ1A; ERBB4; ZNF652; ZNF148; RYBP; BIRC2; HMBOX1; HMGN3; CRY1; KLF6; TOB1; ZFPM2; MXD1; HDAC2; YBX1; PAX5; ZNF131; WWP1; SOX10; ITGB3BP; ARID5B; BMI1; HOXB2; NFAT5; WWC1; MYB; ZBED2; TAF1D; IRF8; ZNF423; UBE2B; SP100; YAP1; CTR9; MEF2A; HTATIP2; CITED2; PEG3; BAZ2B; ESR1; ZNF3; MEIS1; WT1; CBFB; ZSCAN31; TRIP6; XBP1; HOXC6; ASCL1; AHR; FOXC1; TOX3; TCF4; HOXA10; CEBPZ; ZBTB18; TBL1X; TRIB3
Down-regulation	168	FOXM1; TP53; CENPF; NFKBIA; PRPF6; SMARCA1; NFE2L3; RARB; TCEA2; RHOA; DLX4; RUNX3; SLC2A4RG; ZNF302; SOX13; FOSL1; SSBP3; ZNF580; EYA2; RFXANK; TLX1; JUND; CEBPB; PARP1; ABL1; WNT4; SOHLH2; GMEB2; CEBPD; ZNF93; PBX3; ZNF444; POU2F2; CDX1; ID1; WHSC1; LZTS1; ZNF528; HDAC11; ZKSCAN4; CNOT6; PURA; HIC2; NRF1; RBL1; ZNF768; SATB2; ARID3A; CHAF1B; DBP; ZBTB39; KMT2B; TCF25; GTF2F1; TAF9B; RXRG; SMAD6; DRAP1; CTCF; ZNF227; TCEB2; PITX1; ZNF331; TRIM25; GFI1; PNRC1; NFKB1; PITX2; GABPA; HMGA1; FOXD1; CCNA2; DACH1; FOXF1; E4F1; ZNF274; ELF3; AEBP1; EHMT2; HMGB1; ALX1; TBX2; HBP1; PTTG1; ZNF500; BTG1; PHOX2B; TAF12; MLXIP; RELB; TGFB1I1; PBX1; ZEB2; BCL3; ARID1A; BRD3; THAP11; TAF4; CARHSP1; TFAP2C; IRF2; KAT7; DDX17; NOC2L; EDF1; ID2; ZSCAN9; ZMYND11; PRKDC; FOS; ELF1; GTF2I; PRRX1; NFKBIB; JUNB; SALL1; ELK3; ZNF711; TBP; ZNF264; MYCN; TFCP2; KDM5C; MED1; MAFB; RFX5; PSMC3; VEZF1; BARX1; ZNF217; OSR2; FLI1; DLX5; NCOA6; UBE2I; HDAC4; EPAS1; NKX2-1; KMT2A; USF2; AFF1; NR4A2; VGLL1; REPIN1; ST18; MYBL1; ID3; JUP; MEIS2; CTNNB1; MECOM; EYA1; NR2F6; PQBP1; KDM5A; DLX2; IRF6; MSX1; TRIM28; TSC22D1; CALR; TRPS1; MAF; DNMT1; SOX9; ZFP36L2; ZMIZ1; TWIST1