Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID77016	Ixazomib	GSE92742	NKDBA	Human	24h	10uM	EID0444

Response Information :

Types	Number	Response transcription factors
Up-regulation	145	ATF3; ZNF195; UBE2B; NFE2L1; ZNF136; EGR1; MED13; DDIT3; DNAJC2; NRBF2; TAF11; LDB1; MAFG; ZNF222; CEBPD; USP16; ARID5A; ZNF12; SIRT7; LITAF; INSR; ZNF345; PRDM4; CEBPG; RLF; TRIM33; SOX10; ATF4; ZNF44; BRD4; CHD1; PBXIP1; SUPT5H; PPARG; GATAD2A; ERBB4; ZNF91; POLR3C; RRN3; ZNF304; CIR1; CSDE1; COPS2; ZNF263; BANP; PHF1; CCDC59; E2F3; PIAS1; ZNF232; RBPJ; RBM39; ZNF468; GTF2F1; RSF1; ZNF273; ZBTB43; ZNF224; JUN; TFDP2; HSF2; FOXO1; TAF7; DLX5; ZNF394; ELF4; NFIL3; ZNF410; ZFHX4; JUNB; ZBTB11; ZNF430; VPS72; TCF7L1; RBBP5; CERS6; SP140L; ZNF117; SUPT4H1; SP100; SIRT2; HBP1; HTATIP2; PEX14; FOXO3; CDC5L; ZNF165; ZNF10; MED17; TDP2; HINFP; HMBOX1; ZNF331; NCOA1; HCFC2; SIX2; PCGF1; HIPK1; MBD4; HSF1; TOX3; ZNF350; CBFA2T3; ZNF473; SIN3B; IRF9; ZNF83; EYA1; ZNF652; ZNF211; ELF5; TRIM29; MXI1; HIRA; PEG3; TRIB3; BACH2; FOS; TSC22D2; SPIB; YBX3; TFAM; STAT5A; NFATC1; REL; HIC2; ZNF711; ZIC1; EN1; ERBB2; HEY1; ZNF264; CEBPB; PHIP; FOXJ3; FOXC1; MAF; GABPB1; ZBTB16; PAX8; BTG1; MYRF; TFAP2A; ARNT2; TRPS1
Down-regulation	150	CCNA2; TSC22D3; FOSL1; HMGA2; BRCA1; CBX5; SUV39H1; CENPF; ENO1; BHLHE40; FOXM1; MYBL1; ELF3; ELK3; HOXA10; ERG; HMGB2; SIAH2; PTTG1; WDHD1; ZNF217; DDX17; SSRP1; CDK2; MXD3; CARHSP1; NFX1; RBL1; OVOL2; MYC; SOX11; NRIP1; EZH2; RUVBL1; DNMT1; SP3; IRF2; YBX2; HMGB1; HDGF; ZMYND11; ZNF672; ITGB3BP; PIAS3; PMS1; SAP30; PRMT2; ETS2; PMF1; LZTS1; TFDP1; RBBP4; HNRNPD; RELB; NR2F1; TFCP2; HLTF; SATB1; CBX3; ETV1; ASH2L; HMGXB4; HOXC4; TCF4; DNMT3B; BAZ1B; PATZ1; SMARCA4; ZBTB18; RNF141; TCEA2; AR; ZHX3; WHSC1; NFYB; CHAF1B; PA2G4; PRDM1; CREBL2; NONO; POU5F1B; TGIF1; EYA2; RBBP8; CBFB; ZSCAN18; PRKDC; FOXD1; SMARCC1; RBPMS; ID2; TCFL5; ESR1; HMGA1; RERE; MAGED1; HLF; MEIS1; LOXL2; HIVEP2; KAT7; LIN28A; TAF9B; SLC2A4RG; HMGB3; WWTR1; TLE4; SMARCA2; NCOA4; SPDEF; SMARCA1; GRHL2; EGR4; GTF2I; LMCD1; PCGF2; TBL1XR1; ACTL6A; ZBTB20; YEATS4; HDAC6; DEK; HOXC10; SOX17; ZFP36L1; IFI16; TEAD4; PBX1; MECOM; NFIB; ID1; PURA; ZBTB38; ID3; ID4; TP53; STAT6; CTBP2; MYB; TRIM22; NR2F2; MNAT1; CITED2; LEF1; TBX3; FOXF1; HSBP1; BHLHE41; NR3C1; E2F2