Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76975	Ixazomib	GSE92742	NKDBA	Human	24h	0.3704uM	EID0442

Response Information :

Types	Number	Response transcription factors
Up-regulation	335	TBP; TRIM32; NFKBIA; PUF60; HOXC6; BRD8; SMAD2; ZMYM2; EDF1; DRAP1; NRBF2; TRIM28; NCOA4; ZNF212; NUP62; ZNF189; ZFP64; MLX; BRPF1; IKBKAP; HOXD10; FOXO4; FHL2; ZSCAN5A; ELK1; BCLAF1; CHD1; PLAGL2; NFIL3; KDM5A; ZBTB11; CDK8; RNF4; ZNF292; KDM2A; MED1; ORC2; MYCBP; NFE2L1; PIR; NONO; AFF1; NFAT5; PPARG; SNW1; HSF2; JARID2; RBBP5; ASXL1; KAT5; MMS19; RBM14; MED4; PIAS2; ZNF148; TCERG1; RUVBL2; KLF1; NPAT; XBP1; SP110; PAX8; KAT7; USF2; FOXJ3; PHF8; CTR9; JUN; ARID4A; UBE2B; ZNF473; ZNF23; ZNF639; PHF20; KLF12; ZSCAN31; SNIP1; SETD2; DDX5; COPS2; TRIM16; PATZ1; NFYC; UIMC1; C1D; CRY1; MGA; GABPB1; MAGED1; NR2F2; ZNF629; MSL3; SMARCE1; ZMIZ2; ZNF764; MED23; YWHAB; BIRC2; TMF1; ZBTB20; KDM5D; CREG1; SREBF1; ECD; SSX1; ZSCAN16; STAT5A; POLR3F; CDK7; ZNF236; NCOA6; BBX; ZBTB24; TCF25; BTAF1; CREBZF; BATF3; LPIN2; ERCC3; MITF; HIVEP2; PCGF2; MED6; HMG20B; REST; ZSCAN12; DDIT3; KDM4A; EP400; ZNF783; NRF1; RBPJ; HABP4; CCDC59; EP300; CUX1; SMARCA2; TEAD1; RNF111; ZNF267; TRAK1; BCL10; PPARGC1A; ZNF266; NACA; ZNF652; ZNF646; BRD2; ZNF16; ADNP; ZBTB43; BRD3; ZNF3; SCAND1; MED7; ABL1; SMARCA4; YBX1; UBE3A; ELF1; TSC22D2; SMARCD3; PHOX2A; FOXO3; HOXD3; MYC; KAT8; E2F6; TCEB2; PMF1; TRIM33; BLZF1; NEDD8; DNAJC2; DNMT3B; ZNF226; UBE2I; ZNF184; TRIP4; TBL1XR1; NR1I2; ERBB2; AGO2; CREB5; MNX1; ZNF274; ZNF200; RELA; ZMYND8; PSPC1; TRIM27; ZNF468; MTA1; EYA1; GTF2IRD1; MAFG; ATF5; FOXD1; MAX; SP100; PBRM1; ATF2; SP2; PCBD1; SFPQ; LDB1; ATF4; HCFC2; HLTF; DPF2; MED24; BAZ1A; GTF2A1; MNDA; ZNF410; NFRKB; RB1; WT1; RNF10; ZNF408; ZNF721; HSBP1; NKX3-1; SIX2; BATF; SND1; RFC1; ZEB2; SUPT4H1; SOX12; PIAS1; ZNF45; DNAJC1; BTF3; ZNF263; WWC1; CNOT2; ENO1; VGLL4; BASP1; NPM1; ZNF248; MAZ; MXD4; BAZ2B; KLF10; TRRAP; TLE1; TSG101; TGFB1I1; NCOR2; KLF2; TBPL1; YAF2; MTDH; E2F3; ZNF35; ZNF302; NR1D2; SP3; TSC22D4; LEF1; CLOCK; TAF11; ZNF419; CHD7; EMX2; MAFB; HMGXB3; MAF; CCNC; EGR3; AATF; RBBP4; STAT3; JUNB; VEZF1; SMAD4; DR1; SMAD3; TFDP2; RBM39; ZNF552; CERS6; SMAD7; TAF10; RSF1; PFDN5; SIRT7; PIAS3; ARID4B; ZBTB18; HOXB7; TOB1; HTATIP2; RAN; GTF3A; TAF7; ZNF587; GATAD2A; RLF; TBL1X; LITAF; NFIB; JUND; SP140L; NR2C1; CNOT6; ZFX; PLAGL1; PSMD9; SOX4; MSX1; KMT2A; SAP30; RRN3; PA2G4; COPS5; TCF7; HDAC4; MXI1; SATB1; ETV5; TSC22D1; TOX3; ZNF394; TADA3; ZNF160; RUNX3; IRF4; ZBTB38; RREB1; TP53; CITED2; ATF3
Down-regulation	310	TFAP2A; MEIS2; IRF9; ARL2BP; DACH1; IRF6; PRDM14; NR1H2; MYBL1; RAD21; RARG; CENPF; FOXF2; TULP3; ZNF232; CREBL2; BNC2; TCF21; SPDEF; ZNF665; LHX3; SALL2; WNT4; ZIC3; E2F4; CDIP1; ZNF816; RBFOX2; NFATC4; FOXM1; FOXH1; SRF; AEBP1; TAF5L; VGLL1; MLLT10; EHF; SOX17; CBFA2T3; TCEA2; THRB; ETS1; FUBP1; ID3; PSMC3; TAF6L; TCF3; CDK9; ATN1; BRWD1; TCEA1; PRDM2; E2F5; ZNF117; TP73; ERBB4; CAMTA2; SOX13; BARX1; VENTX; TCF7L1; TERF1; XRCC6; NR2F1; PBX3; TEAD4; CREB1; SNAI1; HIPK2; ZNF74; SRY; TRPS1; ZNF331; ELK4; NFYB; ZNF589; GATA6; ZNF75D; TAF1; EMX1; SOX3; NEUROD1; ZNF688; CNOT3; CBL; ZSCAN18; ZMIZ1; EN1; ACTL6B; TBX1; ZNF141; ZNF510; KLF3; HIC2; HOXD13; NFATC3; LIN28A; ZNF180; TGIF2; SOX2; CHD2; AES; TFDP1; SNAI2; ERF; CREM; ZBTB17; FEZF2; SIX6; SHOX2; NR4A3; PHIP; AHR; IFI16; ZBED2; TGFB1; ZNF654; CEBPD; HOXA1; NR2F6; HMGB2; DLX5; ASH1L; HSF4; ARRB1; NEUROG1; SUV39H1; SUPT6H; RFX1; E2F8; ZNF223; TOX; HMGB1; IRF3; SKIL; EGR4; WDHD1; ZNF91; TWIST1; MECP2; ID4; NFYA; TAF9B; CBX7; ZXDC; TAF1C; FOXA2; TERF2; HLX; CUX2; NAB2; OVOL2; MED21; NHLH1; ZSCAN9; TAF4B; BNC1; SSRP1; NANOG; YEATS4; MYBL2; MBD3; ZNF273; E2F1; FOS; ZNF415; ZEB1; KAT2A; TFCP2; ZNF239; GTF2I; ZNF22; KDM5C; FOXG1; TAF12; PRRX1; SOX15; ZBTB3; SNAPC4; PAX6; PPARD; PRDM1; FOXJ2; PRDM12; REL; FOXN3; HMGA1; HOXB5; INSM1; ARNTL2; RUVBL1; ATOH1; RBBP8; SUMO1; NFE2L3; PITX1; RING1; SUPT3H; LMCD1; ERG; GRHL2; ARID1A; ZNF557; TP63; ZNF835; ZNF131; GMNN; MAP3K10; ZNF671; MYRF; CDX1; TCF4; TBX21; MED12; ZFP69B; NR4A1; RORC; ZNF34; ASCL1; PEG3; PIAS4; ST18; CIZ1; ZNF623; ZHX2; PMS1; HOXC4; MED14; ZNF32; SLC2A4RG; WDR77; SSBP2; SOX18; UBTF; ZNF85; VPS72; NFE2L2; PPP1R13L; CAPN15; ZNF43; EPAS1; ZNF195; ARID3B; HSF1; ZNF124; ZNF253; STAT2; ING4; CCNA2; GLI2; SMARCB1; ZNF692; FOXE1; KLF13; DNMT1; CREB3L2; NR0B1; CDK2; IRF8; TRIM22; ILF2; HOXD1; BACH1; PAXBP1; ID1; LOXL2; FOXF1; MKL2; KLF6; PAWR; TTF2; DEK; NR4A2; MEIS1; HOXA4; HLF; MYCN; BHLHE41; ZNF586; TBX3; HDAC9; STAT4; TAF5; PCGF3; HEY1; SSBP3; PRKDC; ESR1; PBXIP1; ACTL6A; EGR2; SMARCA1; PBX1; NR5A2; HOXB13; ETS2; KLF4; VDR; KLF5; IRF7; POU2AF1; TFAP2C; MYCL; ZIC1; BCL11A; MECOM; KLF9; HHEX; DLX2; HOXB2