Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76974	Ixazomib	GSE92742	NKDBA	Human	24h	1.1111uM	EID0442

Response Information :

Types	Number	Response transcription factors
Up-regulation	302	HOXC6; PUF60; NFKBIA; TRIM32; IKBKAP; BRD8; RNF4; TBP; EDF1; ZFP64; DRAP1; ZNF629; KAT7; NONO; ZNF212; PIR; ZNF16; TRIM16; KAT5; HDAC3; ZSCAN5A; CHD1; XBP1; TCF25; SNW1; NFE2L1; FHL2; ZMIZ2; CTR9; ZNF267; NRBF2; IRX5; TCERG1; PAX8; PCGF2; UIMC1; SNIP1; ZNF473; KDM5A; ZMYM2; E2F6; BRPF1; BHLHE40; FOXO4; TRIM28; BCLAF1; KDM4A; ZNF148; MED6; HMG20B; ZBTB40; MLX; MMS19; JUN; ZNF764; AFF1; PMF1; SETD2; ERCC3; NCOR2; DNAJC1; PPARG; CEBPZ; ETV1; C1D; CDK7; MED4; USF2; DNAJC2; ZNF45; TCF15; SETD3; RUVBL2; ZNF263; BATF3; NFKB2; ETV5; LIMD1; MAGED1; PHOX2A; MAX; FOXJ3; UBE2I; MNX1; NR3C2; UBE2B; RB1; ZNF292; SIX1; ZNF266; NEDD8; PIAS2; HLTF; UBP1; ZNF12; MED1; ZNF189; ELK1; MXD4; ING1; NFYC; SP110; BRD2; ATF4; ZNF384; EYA1; EZH1; NFIL3; CREB3L1; ADNP; ZSCAN31; HOXD10; NR2F2; REST; MAFB; ZNF443; PLAGL2; HSF2; SMAD2; BIRC2; MED7; SMARCE1; ZSCAN32; SIX2; RHOA; APEX1; ZNF200; CIITA; SREBF1; ENO1; DPF2; CBX3; CREG1; ZNF646; ETV4; HMGXB3; KAT8; RBPJ; USP16; GTF2F1; SND1; ZNF35; SAP130; ADRB2; SFMBT1; COPS2; RBBP7; ZNF7; MED23; PQBP1; CREB5; KLF12; SFPQ; ZNF516; SP2; ZNF184; ABL1; MNDA; TBL1X; MEOX1; ZBTB43; THAP3; PRPF6; NFAT5; BBX; ZNF408; GATAD2A; PHF20; PCGF1; AGO2; ZNF468; SSX1; LPIN2; HDAC7; PIAS3; DAXX; ZNF446; WT1; BLZF1; TFDP2; JARID2; KLF2; AATF; POLR2A; HOXD3; GABPB1; PBRM1; HCFC1; ZNF14; SMARCA4; MYC; SMARCD1; ZSCAN12; HOXC10; ZBTB39; SCAND1; PIAS1; TRIP4; GTF2IRD1; MAML1; SMARCD3; ATF5; SIN3B; SP3; PFDN5; TGFB1I1; CNOT6; SIRT7; TAF7; TBPL1; NPM1; BANP; ECD; NELFB; HAND1; TSC22D4; KMT2A; TXNIP; TAF11; FOXO3; TBX3; NCOA6; DDX54; ZNF335; PCBD1; RELA; HDAC4; YBX1; BCL11B; RXRA; ITGB3BP; TCEB2; ZNF3; NSD1; CCDC59; CDYL; TSG101; MGA; WWC1; SALL1; PHF1; TLE1; LDB1; HTATIP2; SIRT2; HEY2; ZNF226; TEAD3; SP140L; ING2; HDAC1; RUNX3; TCF12; VGLL4; TCF7; RNF10; MEN1; CENPB; FOXC1; HOXB7; DDIT3; PSMD9; SIAH2; ZNF394; RCOR1; ZBTB1; SOX12; SAFB2; JUNB; BMI1; NKX3-1; RREB1; SAP30; SUPT4H1; HSBP1; ZMYND8; MXI1; RSF1; NR1D2; E2F3; NFE2L3; HMGN3; KDM5D; SUB1; CLOCK; MAZ; BTG1; CRYM; ZNF587; MITF; BASP1; ZHX2; MSX1; HMGXB4; ZBTB38; RORA; ESR1; IRF7; BCL11A; TSC22D1; SOX9; OSR2
Down-regulation	285	PDLIM1; RAD21; TFDP1; DACH1; ZSCAN18; CRK; VGLL1; CDIP1; E2F4; PBX3; ZNF74; GATA6; ID3; IRF6; SNAI1; TCF21; LHX3; ZNF223; ETS1; CBFA2T3; NFIX; ARL2BP; FOXF2; CENPF; ZNF665; CAMTA2; BNC2; SNAI2; ZEB1; ZNF117; SPEN; LMCD1; CARF; CNOT3; SPDEF; KAT2A; FOS; MEIS2; BRWD1; NR2F1; ZNF692; HMGB2; MYBL1; NFE2L2; ZMIZ1; CREBL2; EN1; NR1H2; POU3F2; AEBP1; ZNF667; NFYB; TULP3; BRIP1; PRDM14; FUBP1; FEZF2; EHF; ZIC3; E2F1; NEUROD1; SIX6; SOX17; NFATC4; PAX6; KLF11; ZNF225; BRCA1; NHLH2; ST18; TCEA1; KLF5; ID4; ZBED2; HIPK2; PRDM13; IRF9; EMX2; MECP2; MLLT10; TRPS1; NEUROG1; TAF1; ZNF85; TEAD4; ACTL6B; LHX2; INSM1; FOXG1; BACH1; RFX1; SOX3; FOXA2; SRF; REL; CAPN15; SRY; EMX1; TGFB1; SUV39H1; ZNF816; TFAM; NFX1; SKIL; MBD3; ZNF573; NKX2-1; ZBTB20; ZNF75D; EYA2; TOX; CUX2; KLF9; ZNF345; IRF3; PRDM2; MDM4; ZNF415; ELF4; GTF2A2; EGR4; ATN1; SMARCB1; ZNF232; TP73; ZNF654; HMGA1; ZNF281; YEATS4; FOXM1; ERG; ZNF835; CALR; LOXL2; SHOX2; PRRX1; RARG; NFE2; ZNF43; CNBP; ZNF91; NLK; POLR3C; ZNF529; ZSCAN9; CREB1; DLX5; ZNF83; HES1; PAWR; ZNF264; NR4A3; SUMO1; PRDM12; TCF7L1; TCEA2; MYT1L; E4F1; PPARD; ZFP36L2; OVOL2; LIN28A; NR2E1; ARID5B; TAF4B; CCNA2; KLF13; ZIC1; DEK; HMGB1; CDX1; CBFB; PSMC3; ZNF10; ZNF273; HOXA10; TAF1C; ID1; ZNF224; ZNF22; PSIP1; TTF2; ZNF180; KLF6; HSF1; SOX2; TAF9B; ZNF32; HIRA; HMGB3; C1QBP; TLE2; ZNF34; ELF3; SALL2; NFATC3; TERF2; TRIM22; FOSB; SMARCD2; ZNF331; ZKSCAN1; SUZ12; NR0B2; HDAC9; RCOR3; PPRC1; VPS72; ZFPM2; ASH2L; NR4A1; SOX11; SMAD4; BNC1; PPP1R13L; KLF4; PBX1; AHR; HIC2; PTRF; HIPK1; KMT2B; PAXBP1; TP63; ENY2; IFI16; MYBL2; PLAG1; NR2F6; HLX; FLI1; ZNF195; DMTF1; HHEX; NFIB; ZNF551; ZNF623; CBFA2T2; NANOG; SSBP2; MEIS1; VDR; GLI2; MYCL; CHD7; ZNF93; NCOA2; SOX13; ZNF124; RBPMS; ASCL1; ZNF177; TBX2; ERBB4; FOXN3; BACH2; NR5A2; POU2AF1; EPAS1; DNMT1; FOSL1; TSC22D2; TAF9; KLF7; GTF2I; ZNF586; WWTR1; ZNF131; FOXF1; TCF4; TGIF1; SOHLH2; SPIB; PRKDC; BCOR; MAFF; MYRF; ETS2; ZNF329; EGR2; IRF8; HOXB2; HEY1; HOXA5; DLX2