Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76973	Ixazomib	GSE92742	NKDBA	Human	24h	3.3333uM	EID0442

Response Information :

Types	Number	Response transcription factors
Up-regulation	251	PUF60; TBP; ZMYM2; NFKBIA; BRD8; SMAD2; TRIM32; NONO; KDM5D; CHD1; PIAS2; EDF1; SNW1; NRBF2; RNF4; FHL2; ZNF212; ATF4; ZFP64; DRAP1; BCLAF1; RBBP5; PIR; SNIP1; PHF20; MMS19; XBP1; TCERG1; PAX8; LPIN2; KAT5; KDM5A; HOXD10; ASXL1; MSL3; ZFY; HCFC2; COPS2; KDM2A; IKBKAP; FOXO4; MLX; RUVBL2; EZH1; HSF2; MYCBP; ZBTB40; CDK8; NUP62; ZNF473; NCOR2; UBE2B; YBX1; PMF1; ZNF45; ZBTB20; DNAJC2; NFE2L1; SP110; TRIM16; FOXJ3; UBE3A; BCL11B; ALX1; ZNF23; RBPJ; SCAND1; JUN; HOXD3; NFYC; ZNF721; ZNF764; MED4; E2F6; CRY1; ZNF516; PIAS1; MAGED1; ZNF148; HMG20B; GTF2F1; RB1; SSX1; MAF; SP2; ZNF266; GTF2IRD1; MYC; RBM14; SETD2; SIX2; DNAJC1; CNOT2; NCOA4; MEOX1; IRX4; RFC1; DDIT3; ZNF226; SMARCE1; BRPF1; ZNF267; ZNF652; TCF15; SOX10; YBX3; BIRC2; UIMC1; RNF14; ZNF3; CCDC59; EYA1; SOX4; ABL1; TBPL1; BRD3; PPARG; RFX5; RXRG; MED6; TEAD1; ZNF44; MAFB; NCOA6; GABPB1; NEDD8; CREB5; TRIP4; TCF7; PHF8; SND1; ING3; ZFHX4; MED23; NFRKB; PCGF2; TBL1X; NKX3-1; MED1; ERCC3; RBBP4; CEBPZ; NFAT5; ZNF611; MAFG; MED24; AFF1; LEF1; BANP; PRPF6; ZMYND8; BRD2; CREG1; TGFB1I1; NPM1; FOXO3; ZNF12; PBRM1; ZNF263; BATF3; JARID2; KAT8; SOX5; CTR9; ZNF410; SREBF1; ZNF160; CUX1; SIRT7; RORA; SNAI2; RHOA; LITAF; BBX; TBL1XR1; RBBP7; NR2F2; ZNF394; DDX5; DPF2; APEX1; GTF3A; TCF12; TSC22D4; SMARCA2; TLE1; ADNP; VGLL4; RXRA; BTF3; MAX; RBM39; HDAC4; ZMIZ2; USP16; SMARCD3; MITF; TRIM29; TFDP2; HDAC1; RLF; AIP; TAF11; ENO1; MTF2; NR2C1; RNF10; E2F3; SMARCA5; CITED1; PHF1; RUNX3; KMT2A; NCOA2; TBX3; WT1; MLXIP; MAZ; RSF1; CEBPG; MNDA; CNOT6; ZNF24; ISL1; ZNF302; JUND; HTATIP2; ATF3; TSC22D2; SMAD1; ARID4B; YWHAB; PCGF1; SP140L; ZNF587; MXI1; BAZ1A; ZBTB18; MEOX2; COPS5; ZNF430; SUB1; ETV5; SAP18; HOXB7; SATB1; CERS6; PLAGL1; TSC22D1; HOXA5; TP53
Down-regulation	269	MEIS2; VGLL1; E2F4; TCEA2; IRF9; CREBL2; TAF5L; CENPF; KDM5C; GATA6; IRF6; CSDC2; FOXF2; EZH2; TAF1C; CALR; DACH1; ZSCAN9; ACTL6B; ARL2BP; FOXH1; TFAP2A; RARG; BNC2; ERBB4; TCF3; SALL2; NFYB; MYBL1; HMGA1; CNOT3; NR1H2; SRY; ZSCAN18; SNAI1; FUBP1; LHX3; GRHL2; TGFB1; ELK4; KAT6B; RAD21; FOXM1; CBFA2T3; NFATC4; ETS1; RUVBL1; SUV39H1; TRPS1; ZXDC; THRA; SUMO1; SOX3; BRWD1; TCF21; SOX15; SPDEF; ZNF444; SOX17; PRDM14; ATN1; ZNF239; AHR; EHF; CDIP1; SRF; E2F1; SIAH2; PAX6; SPEN; MLLT10; SLC2A4RG; PEG3; SMARCC2; MYT1L; SHOX2; ASH2L; CDK9; NOC2L; DLX5; PPP1R13L; FOSL2; TEAD4; ZNF606; ZNF816; NFE2L2; ZMYND11; TFDP1; NAB2; ID4; TOX; VAX2; BRIP1; HMGB2; EMX1; EGR3; SOX13; NANOG; OLIG2; PPARD; HIPK2; THAP10; TULP3; ZNF331; NR4A1; HLX; SUPT6H; ZMIZ1; PSMC3; NEUROD1; OVOL2; PSIP1; LIN28A; FOS; ZNF85; MBD3; GFI1; ZZZ3; MYBL2; EHMT2; PPRC1; ZNF75D; ZNF180; ZNF667; ZIC3; CDX1; TCEA1; CITED2; PTTG1; ZNF432; ZIC1; TRIM22; BACH1; DEK; NRIP1; PRDM12; MXD3; HDAC9; DBP; PAXBP1; ID3; LMCD1; PMS1; ZNF175; KLF3; PBX3; GTF2A2; HOXC4; ZNF140; BRCA1; ZNF205; ZNF665; ST18; PRRX1; TAF12; CARHSP1; MYNN; MED21; EN1; AEBP1; TFCP2; POU2F2; MED12; SMAD6; SOX2; CAPN15; MYRF; MECP2; WDHD1; MED14; SPIB; ZNF117; NPAS2; ZNF623; SUPT3H; HIC2; TCF7L1; TLE2; ZEB1; BARX1; SSBP3; ZNF557; NFATC3; NR2F1; ZNF350; REL; ZNF692; TBX21; ZBED2; ZNF768; FOXG1; ZFHX3; ZNF415; INSM1; HES1; ZNF22; FOXA2; CREB1; CCNA2; NCOA3; PBX1; SMARCB1; PAWR; CBX5; KLF13; PRMT2; E2F8; TERF2; ACTL6A; SMARCD2; KDM5B; LOXL2; SMARCA1; ELF5; ZNF93; ZNF33B; GTF2I; TTF2; NR2F6; SOX11; ZNF195; CEBPE; PNRC1; VDR; ETS2; MEIS1; KLF4; ZNF586; MNAT1; NR1H3; CERS4; NR5A2; DLX2; SSBP2; HMGB3; TGIF1; VPS72; ESR1; ASCL1; ZNF512B; ZNF177; ZNF281; FOXF1; SREBF2; RBBP8; TBX2; KLF9; FOSB; TAF9B; CDK2; HOXB6; SOHLH2; IRF8; ID1; MAFF; WWTR1; DAXX; FOXN3; ZNF131; GLI2; MYCN; NR4A2; EPAS1; HOXB2; MYCL; MECOM; HHEX; HEY1; EGR2