Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76972	Ixazomib	GSE92742	NKDBA	Human	24h	10uM	EID0442

Response Information :

Types	Number	Response transcription factors
Up-regulation	383	HOXC6; TBP; PUF60; ZMYM2; TRIM32; EDF1; BRD8; NRBF2; SNW1; BRPF1; ZNF189; DRAP1; TRIM28; NUP62; NFIL3; SMAD2; NONO; ATF4; ORC2; IKBKAP; PIAS2; BCLAF1; RUVBL2; MLX; ZBTB11; CHD1; NCOA4; ZBTB40; MED1; ZFP64; KDM2A; KDM5A; FOXO4; MED4; JARID2; ZNF212; NFE2L1; COPS2; RBM14; LPIN2; KAT5; HCFC2; SETD2; PSPC1; RNF4; PAX8; PCGF2; CTR9; PPARG; CRY1; KLF12; USF2; BATF3; FOXD1; ING1; ELK1; FHL2; DNAJC1; NFKBIA; KDM5D; TRIM16; TCERG1; ASXL1; NCOR2; KAT7; XBP1; KDM4A; ZSCAN5A; HSF2; MMS19; ZNF267; HLTF; MED6; FOXJ3; AFF1; GABPB1; BRD3; YBX1; ZNF629; ZNF516; RBBP5; ZNF292; RNF111; UIMC1; NFYC; SNIP1; NCOA6; HOXD10; BMI1; RNF14; MSL3; SETD3; ZEB2; ZNF764; ALX1; PATZ1; PIR; PPARGC1A; RBPJ; UBE3A; RB1; ZNF473; JUN; POLR2A; SMARCE1; PRRX2; ARID4A; RFC1; ZFY; MEF2A; ZNF16; ZNF23; UBP1; CCDC59; SP110; PHF8; SMARCA4; ZNF45; ZBTB24; NRF1; SMARCA2; ABL1; ZNF410; SFMBT1; NFATC1; PLAGL2; MED23; PHF20; ZNF384; KLF2; UBE2B; RNF10; SOX4; MYCBP; ELF1; HMG20B; ZNF672; MAGED1; TMF1; BBX; ZNF639; CREG1; TSC22D2; RHOA; MED24; RLF; DNAJC2; BRD2; DDX5; NEDD8; PMF1; IKZF5; SREBF1; TRIP4; TAF10; NR2F2; ECD; DPF2; CDK8; ZNF226; MED27; C1D; CREBZF; NFAT5; SCAND1; ING3; PHF2; CDK7; ERCC3; SIX2; TEAD1; GTF3A; KAT8; CUX1; VEZF1; HMG20A; E2F6; ZNF148; HOXA7; MYOD1; REST; ARID4B; TBPL1; ATF7IP; SMAD5; MAZ; EP400; BTAF1; CRK; SP100; RBBP4; CNOT2; EN2; PBRM1; RNF6; MITF; TCF15; MGA; ZNF408; TRAK1; RBM39; NELFB; BIRC2; HSBP1; MSX1; TRIM33; NKX3-1; ZNF143; ZNF646; NACA; ZNF263; ZNF443; SP2; NR3C2; ZBTB43; TAF1D; YBX3; FOXO3; SND1; PHOX2B; YAF2; USP22; BCL10; MAF; EYA1; ZMYND8; DNMT3B; ZFHX4; HIVEP2; ENO1; BRF2; AATF; CCNC; SMAD3; TCEB2; HOXC10; UBE2I; STAT5A; IRF1; VGLL4; HOXB7; MTA1; SFPQ; DDIT3; BAZ1A; RELA; TLE1; SIRT7; TRRAP; CREB5; SIM2; BAZ2B; ZMIZ2; EP300; BAZ1B; NFRKB; MYC; ADNP; MTDH; NCOA1; SATB1; HIVEP1; SIX1; SUPT4H1; SMARCD3; NPM1; CIR1; HDAC2; TCF12; SSX1; TBL1X; ZNF7; CEBPZ; NFKBIB; ARNT; TLE4; ZNF184; ZNF446; BTF3; MAFG; HNRNPD; PCGF1; HTATIP2; ESRRG; BASP1; SAFB2; TSC22D1; GTF2IRD1; ATF6; PIAS1; TRAF6; TSG101; SP140L; TBL1XR1; TFDP2; JUNB; RBBP7; WHSC1; HMGXB3; BATF; PIAS3; HCFC1; CARM1; KMT2A; MXD4; YWHAB; DDX54; PSMD9; TSC22D4; BCL3; USP16; FOXC1; MAX; RREB1; TGFB1I1; ZNF468; RXRB; AIP; SALL1; ATF3; RCOR1; SP3; HMBOX1; DR1; CREB3L1; RUNX3; PCBD1; SMAD4; NSD1; PHF1; E2F3; SAP18; ZNF721; TTF1; ADNP2; HDAC1; BANP; PRDM4; TADA3; GATAD2A; ZNF302; ZBTB1; LEF1; ZNF217; ERBB2; ZNF587; ZNF14; MED7; SMAD7; MAFB; JUND; SATB2; SMARCA5; ZNF274; RYBP; WWC1; RUNX1; RFX5; NFKB1; ZNF394; TAF11; TRIP6; ZNF652; CDYL; EMX2; REPIN1; SUB1; ZBTB38; NR2C1; ZNF593; PFDN5; STAT3; ZBTB18; CTNNB1; JAK2; FOXO1; CEBPG; ETV5; LITAF; SAP30; TCF7; TP53; ID2
Down-regulation	343	MEIS2; SALL2; PRDM14; TFAP2A; IRF6; SPDEF; CEBPD; MYBL1; IRF9; BNC2; RAD21; RARG; NFATC4; DACH1; FOXF2; E2F4; CREBL2; TULP3; CDIP1; LHX3; ACTL6B; NR1H2; TCF21; ARL2BP; ZNF665; TRPS1; ZNF74; SRY; ZNF232; ETS1; HIPK2; EHF; ZNF816; FOXH1; RBFOX2; ZNF331; VGLL1; ZIC3; ZSCAN18; CSDC2; GRHL2; PEG3; SOX17; ZNF589; TP73; ERBB4; OVOL2; RUVBL1; AEBP1; TAF5L; SOX13; ZNF117; YEATS4; NFYB; ID4; ZBTB44; GATA6; SOX3; ZNF239; WNT4; ZNF701; ZNF667; NANOG; CBL; TAF6L; BRWD1; ZNF223; CBFA2T3; NR2F1; ZNF75D; BARX1; SOX2; FEZF2; SNAI1; EMX1; TCF3; ZNF573; LIN28A; ZNF180; THRB; ARRB1; ATN1; ZNF343; TAF1C; CENPF; ZXDC; ELK4; NAB2; TCEA2; OVOL1; NEUROD2; TFDP1; KLF3; TGIF2; ST18; ZNF141; ZNF154; PBX3; RFX1; PRRX1; E2F5; DEK; E2F1; MYBL2; SRF; HOXB5; HMGB2; POU6F2; MYRF; PSMC3; KAT2A; BRIP1; ZNF85; NEUROD1; PBX1; SNAI2; OLIG2; FOXM1; ZSCAN9; CNOT3; TAF4B; KDM5C; GTF2I; CALR; NHLH1; ZNF654; VENTX; TCEA1; NOC2L; ZNF43; ZNF215; FUBP1; TAF1; SUMO1; ID3; SOX15; TP63; NFE2L3; CUX2; PROP1; REL; CAPN15; WDR77; ZNF195; JUP; SLC2A4RG; CHD2; CDX1; PRDM12; MED14; GMNN; TAF9B; TEAD4; TOX; SHOX2; TBX5; ZNF345; PAX6; ZNF623; SUPT3H; DLX5; SOX18; HSF4; ZNF571; VAX2; THRA; HDAC9; ZBED2; ALX4; POLR3C; GTF2A2; HOXB1; CREB1; E4F1; NEUROG2; CBX2; ZNF253; CDK9; SMARCC2; FOXG1; ZNF444; ZMYND11; ESR1; TLE2; ZFP69B; FOXE1; NFATC3; BNC1; TDP2; SOX21; ILF2; HIRA; ACTL6A; ZNF257; TERF1; DNMT1; ZNF91; ZEB1; EGR4; INSM1; CBX7; ZNF682; NFIX; ZMIZ1; THAP10; TRIM22; CDK2; ATOH1; HIC2; TTF2; PITX1; SUV39H1; HMGA1; WDHD1; MLLT10; ZNF415; ZNF835; ZFPM2; TBX1; TFCP2; ZNF692; TCF7L1; ZNF235; CAMTA2; FOXA2; TBX21; NR2F6; MBD1; ZNF606; SSBP3; ID1; ASCL1; SKIL; ZNF512B; PRDM2; HMGB1; CTBP2; TCF7L2; TGFB1; CREB3; EN1; SMARCB1; MAP3K10; SIX6; ING4; CCNH; PPP1R13L; HOXD1; KLF13; TLX3; FOS; ZNF22; CBX5; NKX2-1; MED12; RING1; HOXA1; ZNF557; SPIB; PAWR; ZNF140; ZNF273; ERF; ZNF354A; POU5F1B; ZNF268; BHLHE41; VDR; RORC; RBBP8; IFI16; PPARD; ARID1A; ZNF219; ZNF551; CCNA2; ZNF93; PHIP; EHMT2; MKL2; VPS72; MED21; ZNF562; MYCL; NFE2L2; MECP2; ARID3A; PIAS4; NR4A3; CBFA2T2; UBTF; EPAS1; ZNF350; SSBP2; ZNF224; TWIST1; ZNF33B; BCL11A; AHR; NR4A1; PBXIP1; PMS1; ZFP36L2; EGR2; PTRF; ARID5B; ZNF586; MYCN; PRDM1; ZHX2; TFAP2C; CBX4; TCF4; HOXB2; HLF; NR2E1; IRF8; GLI2; ZNF264; HHEX; SOHLH2; ZNF124; PRMT2; NR0B1; HLX; L3MBTL1; ZNF131; FOXF1; LMCD1; ZIC1; YAP1; TERF2; NR4A2; FOXA1; PRKDC; POU2AF1; AR; HOXB6; PAX5; FOXN3; TBX3; KLF9; SOX9