Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76958	Canertinib	GSE92742	MCF10A	Human	6h	0.08uM	EID0441

Response Information :

Types	Number	Response transcription factors
Up-regulation	104	PCBD1; ZNF274; ASH2L; TSC22D3; SMAD1; PHF8; FOXO4; TCF21; HSF2; SALL2; NFE2L1; TP53; MED1; ELF1; PCGF2; MAGED1; AEBP1; MITF; CTR9; SMARCE1; FOXO1; HMGB2; ZNF528; MTDH; TRIP6; RBPMS; PMF1; HDAC6; TRIM29; PTRF; UIMC1; BRCA1; MXI1; NFYC; CITED1; SMARCA2; USP22; MAF; PBX1; PIR; SUV39H1; HOXA5; KAT6A; COPS5; NRIP1; ERBB2; SMAD5; HOXA11; SOX13; PRKDC; BRF2; HDAC9; MTF2; BNC2; HOXD11; PSMC3IP; NCOA4; TP63; EGR2; NKX3-1; RBBP7; ZNF552; TLE4; CDK9; ELF4; TBP; VEZF1; ZBTB16; RLF; FLNA; MLXIP; UBE3A; ZNF32; BIRC2; POU4F1; ID3; SUB1; MYRF; PAXBP1; NR2F2; BAZ1A; MYCBP; RFX5; MED24; ZNF131; LITAF; MSX1; BBX; EDF1; HEY1; ZSCAN18; PSIP1; PEG3; MEIS2; IKBKAP; JUND; SIX1; KDM5D; HOXA10; ARID4B; CRK; TBX3; ESR1; HOXC6
Down-regulation	88	MYC; ZBED2; NKX2-1; ZNF239; ZNF22; MYCL; HOXC10; PIAS4; NFE2L2; HIVEP1; NFKB2; GTF3A; NFE2L3; ZNF586; ZNF124; BASP1; DLX5; ZNF512B; EGR4; MED17; BCL11A; ZNF165; PKNOX1; NEUROD1; BACH1; ZNF74; ERF; ZNF43; THAP4; EHF; REL; ZNF574; MYCN; POU5F1B; LHX6; PAWR; PRDM1; ZSCAN9; TOX3; KLF11; RREB1; SMARCA4; PLAGL2; NFE2; BCL3; ZNF253; HDGF; ARID5B; TLE2; FOSL1; ZNF415; ETV4; YBX1; XBP1; DAXX; PCGF3; SERTAD2; ZBTB38; SATB2; HHEX; MNDA; NKX2-2; HIRA; CREB3L2; ZFP36L2; ZNF217; LIN28A; NR4A1; NFAT5; HIC2; ZNF117; MYT1L; EN1; ID1; HES1; MNT; PHF20; MYBL1; TXNIP; TRPS1; CREM; MECOM; FOS; CREB1; FOXF1; NFATC3; SATB1; NR4A2