Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76957	Canertinib	GSE92742	MCF10A	Human	6h	0.4uM	EID0441

Response Information :

Types	Number	Response transcription factors
Up-regulation	114	ZBTB18; ASH2L; TAF10; PCBD1; TSC22D3; GLI3; HDAC6; PHF8; MAGED1; MITF; HCFC2; HOXA4; AEBP1; TP53; TRAF6; ZBTB25; VGLL4; SPIB; MLXIPL; ZNF8; NFIX; ZNF211; HOXC4; ATF5; NFE2L1; CREB3; ZNF274; HOXC6; FOXO4; PTTG1; ZNF672; TTF2; HOXA5; WHSC1; MMS19; BRCA1; RCOR3; CITED1; ATF7IP; NCOR2; PMF1; BRF2; FOXO1; MAZ; RLF; RBBP8; RERE; C1D; ZKSCAN1; DDX5; SOX10; PIAS2; CEBPG; SPEN; HMGB3; ZNF32; ZNF281; ELF5; THRAP3; HSF2; HMGB1; SMAD1; ERBB2; UBE2I; LDB1; NFYC; BRD4; CTR9; SALL2; MLX; MED1; ZNF140; TP63; TTF1; STAT6; ZNF83; TRAK1; CREBZF; MAFB; BAZ1A; TBP; HEY1; NEDD8; RBPMS; BNC2; MYCBP; HTATIP2; ATF3; NR2F2; KLF7; HDAC1; SAP18; VDR; JUND; MXI1; PSIP1; BACH2; CENPF; MLXIP; PAXBP1; FOXN3; ARID5B; ZSCAN18; TCFL5; TSC22D2; RUNX1; RHOA; ARID4B; IKBKAP; CRK; PIR; CITED2; LEF1; THAP11
Down-regulation	103	MYC; MNDA; FOXF2; NFKB2; TGFB1; OSR2; ETS2; NR0B1; NFE2L2; ZNF623; SMARCA1; ZBED2; BHLHE41; ZNF611; RAD21; REL; ELK3; CREM; RREB1; CAMTA1; ZNF512B; NKX2-1; BACH1; TBL1X; THAP4; SOHLH2; HHEX; BASP1; NKX2-2; NR4A2; ZNF248; ZNF586; HMGA2; SMARCD3; PEG3; ZNF711; PAWR; NEUROD1; ZNF124; ZFP36L1; FOXF1; TLE2; LIN28A; URI1; ZNF160; BCL3; HDAC4; ZFPM2; ZNF573; DAXX; PRDM1; BCL11A; SOX11; NFE2L3; IRF1; MECOM; ID1; NR4A3; WWTR1; ZNF721; TFAP2C; DACH1; NR4A1; NANOG; DNAJC2; EPAS1; KAT2B; XBP1; RBPJ; ETV5; FOXL2; KLF10; PAX6; ETV4; AES; ERBB4; ELF3; TEAD4; FOSL1; TGIF1; HOXD1; TRPS1; MYT1L; HOXD3; SOX9; ID4; WT1; ZNF652; HES1; PHF20; PLAGL1; ZNF331; PHIP; MYCN; NR2F1; PBX1; MYBL1; NFATC3; MEIS2; MEIS1; EGR3; TBX3; SATB1