Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76956	Canertinib	GSE92742	MCF10A	Human	6h	10uM	EID0441

Response Information :

Types	Number	Response transcription factors
Up-regulation	106	TAF10; PCBD1; ASH2L; PHF8; BRD2; TSC22D3; HOXA4; DDIT3; TRIM29; TOB1; ZNF394; HDAC6; ATF5; AIP; HCFC2; TRRAP; HMG20B; ARNTL; NFE2L1; SRF; NR2E1; SALL2; STAT1; EZH1; APBB1; HDAC9; DDX5; ZKSCAN1; TSC22D4; HOXA5; MAZ; CEBPG; AEBP1; PTTG1; PEX2; BRD8; PIAS2; DNMT1; ZSCAN18; BTAF1; KDM2A; MLXIPL; ZNF274; ZNF32; CITED1; RNF141; MAGED1; USP22; HDAC5; ATF4; SPEN; SPIB; NR2C1; PRKDC; ST18; FOXD1; EMX2; CTR9; BRF2; NFYC; CRY1; JUND; KAT6A; MED1; HMGB1; KMT2B; CENPF; ERBB2; TBP; ATF3; MXI1; PBX3; BRD4; SUPT3H; NKX3-1; MYCBP; DMTF1; HTATIP2; COPS5; ZNF384; ZNF83; HOXC10; MEOX1; NCOR2; NR1H2; FOXN3; KLF7; RBPMS; SIX1; SAP18; CD3D; HOXC6; SAP30; RFX5; TSC22D2; EZH2; FOXO1; PIR; PBX1; TWIST1; KDM5D; PSIP1; IKBKAP; ARID4B; THAP11; CRK
Down-regulation	106	MYC; BACH1; ETS2; NFE2L2; NKX2-1; AHR; REL; NFKB2; BASP1; ZNF512B; ZBTB38; GRHL2; MNDA; ELK3; TXNIP; OSR2; SOX11; UBP1; CREM; TFAP2A; ZNF611; TGFB1; NFE2L3; ZNF586; CARM1; ZNF43; ZSCAN31; FOXF2; NKX2-2; ZNF180; NFAT5; ZNF623; TLE2; HMGA2; HHEX; CEBPZ; KAT2B; OVOL2; KLF10; THAP4; POU2F1; EPAS1; FOXA2; FOXC1; ZNF160; NR4A2; ID1; SP3; TFAP2C; ETV4; ZNF124; RREB1; BCL11A; DAXX; URI1; BCLAF1; PAWR; NR4A3; TOPORS; RBFOX2; PCGF3; TGIF1; TEAD4; NR4A1; EHF; ZNF117; EGR2; CTNNB1; FOSL1; SIAH2; ZBTB20; CHD9; ZNF292; NR1D2; TRIM32; LIN28A; DLX5; SMARCA1; NEUROD1; ZBED1; FOXF1; ARID5B; PAX5; PHIP; ZNF331; HES1; BHLHE40; KLF4; HIRA; TRPS1; ESR1; NR2F1; ID4; PHF20; MECOM; DACH1; CREB1; MEIS2; ERBB4; NFATC3; FOS; TBX3; HOXA10; ZNF423; SATB1; TSC22D1