Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76943	Azd-8330	GSE92742	MCF10A	Human	6h	0.08uM	EID0441

Response Information :

Types	Number	Response transcription factors
Up-regulation	123	ASH2L; ELF1; TOB1; FOXO1; WDHD1; TP53; HSF2; NFE2L1; HCFC2; TSC22D3; TAF10; ZNF184; MED7; THAP1; BNC2; BRCA1; MITF; YEATS4; ZNF764; ZNF268; SMAD5; ADNP2; KAT7; PDLIM1; SMAD1; RBM14; SNIP1; CRY1; RBL1; PCGF2; SUB1; PIAS2; MAGED1; NRBF2; PSMC3IP; RFC1; HDAC6; SP2; PRKDC; TMF1; SETD2; CUX1; SALL2; ZNF468; RLF; TAF9B; GABPB1; TAF11; MED1; RCOR3; AFF1; USP22; ZSCAN12; ZBTB11; EYA2; MAF; RBBP5; MED24; ZNF23; ZNF281; BRF2; RNF10; GFI1; MLLT10; MLXIP; KAT6A; MXI1; RNF14; NCOR2; BRD8; ZBTB1; CITED2; HMGB1; TAF7; RSF1; LITAF; CNOT2; ZNF304; RFX7; MSX1; RBBP4; NUP62; VEZF1; CREBZF; NFATC3; ELF4; RBPMS; TBP; SCAND1; HOXB7; CEBPG; RFX5; BCOR; ANKRD1; ZNF274; HOXC6; ZBTB18; ING2; ZNF140; WWC1; RBBP7; AEBP1; CREG1; ATF3; RRN3; ESR1; ZNF131; CENPF; MYRF; TBPL1; IKBKAP; ATF1; PSIP1; HTATIP2; ID3; ARID4B; PIR; KDM5D; TLE1; TLE4; THAP11; WT1; CRK
Down-regulation	95	MYC; SOX9; BASP1; TOX3; BCL11A; ATN1; FOXA2; HIRA; REL; ELF5; NFKB2; ETV4; BHLHE41; ZNF430; ZNF623; ST18; SOX11; NFE2L3; CALR; CDX1; FOSL1; ZNF264; TGFB1; NKX2-1; SSBP2; PREB; PRDM1; ZBTB38; CREBL2; HMGA2; ZNF239; FOXF2; ZNF22; SALL1; TFAP2A; MNDA; ZNF93; TLE2; EPAS1; NKX2-2; E2F6; MYCL; CNOT3; NR2F1; PEG3; HHEX; XBP1; WWTR1; PRRX2; CREM; PROX1; TCF20; PRDM2; TRPS1; ZFP36L2; PAX6; TRIM27; ELK3; HSF1; MEIS1; FHL2; EHF; TBL1X; ETV5; MYCN; SMAD6; LIN28A; DAXX; ZEB1; ARID5B; NFAT5; DACH1; ZNF91; FOXC1; ZNF652; IRF6; ZNF331; CTNNB1; TCF7; ERBB4; HIC2; HMGA1; EN1; FOS; TFAP2C; FOXF1; SATB1; DMTF1; CREB1; NR4A2; ZIC1; ID4; TCF4; ZNF423; KAT6B