Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76940	Azd-8330	GSE92742	MCF10A	Human	6h	10uM	EID0441

Response Information :

Types	Number	Response transcription factors
Up-regulation	124	ASH2L; TRIM29; PCBD1; TAF10; NFE2L1; HDAC6; AEBP1; PHF8; TRAF6; CREB3; ZNF274; TOB1; TTF2; HDAC9; VGLL4; TADA3; BRD8; AATF; MTDH; PEX2; NR2E1; HEY1; AFF4; TAF4; FOXO4; ATF5; TSC22D3; MBD2; BRF2; ZBTB24; MNAT1; MED1; BRD4; NCOR2; WHSC1L1; MAGED1; BMI1; SMAD1; PRKDC; ADRB2; ZNF473; ZNF394; CTR9; RFXANK; CAPN15; TP53; NUP62; RFX7; FOXN2; NRIP1; TWIST1; C1D; MAFB; PTTG1; ZMIZ1; MITF; RLF; ZNF177; SMAD5; AIP; NCOA6; EZH1; TMF1; DDIT3; SALL2; USP22; CITED1; SREBF1; TBP; HSF2; KDM2A; ARNTL; CHD4; KLF7; ELF4; SP2; SCAND1; ZNF83; NKX3-1; HOXC6; CUX1; MYCBP; MED24; HOXA5; SUV39H1; VEZF1; TP63; ZNF432; HMGN3; EMX2; BIRC2; SAP30; SAP18; ZNF140; SMARCA2; NEDD8; ZNF281; TFAM; RBBP7; RBPMS; JUND; NCOA3; SIX1; CDK9; ZNF302; TCFL5; BRCA1; HOXB7; BAZ1A; TBPL1; LEF1; PSIP1; CITED2; IKBKAP; ARID4B; NR1D2; RUNX1; PIR; KDM5D; ID3; CRK; RHOA; ATF3; TLE1
Down-regulation	98	MYC; LIN28A; VPS72; NKX2-1; NFKB2; GLI1; NKX2-2; SMARCA1; NFE2L2; FOXF2; HHEX; FOXC1; BACH1; SMARCD1; NANOG; BCL11A; ZFP36L1; HDAC7; SSBP2; SMARCD3; EPAS1; EVX1; SOHLH2; TBL1X; REL; KAT2B; ZNF586; POU5F1B; ZNF74; HMGA2; TAF1A; BARX1; NFE2L3; ELF5; ZNF512B; MNDA; RBPJ; ELK3; SOX10; MYBL1; ZZZ3; FOSL1; TGFB1I1; ETV5; NR0B1; SALL1; XBP1; DAXX; PITX2; TCF15; EGR3; CREM; CREBL2; RREB1; TGIF1; NPAT; CHD9; ZNF124; TERF1; NEUROD1; ETV4; CTNNB1; KLF4; ZNF93; KLF10; SMAD7; PCGF3; NR4A3; RNF138; FOXF1; ZBTB20; ID4; TRPS1; DNMT3B; CREB3L2; RORA; NAB2; NR4A1; PEG3; MYCN; PHIP; EN1; FHL2; PLAGL1; CD3D; PAX6; DMTF1; TFAP2C; POU2AF1; GATA6; TCF4; NR2F1; TBX2; MEIS2; SATB1; ESR1; NR4A2; THAP11