Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76923	Vx-745	GSE92742	MCF10A	Human	6h	0.08uM	EID0441

Response Information :

Types	Number	Response transcription factors
Up-regulation	192	HDAC6; IKZF1; TAF10; ASH2L; JARID2; TOB1; ZNF143; MNAT1; TCERG1; PHF8; MAGED1; NUP62; MED1; ETV1; ZNF672; EGR1; BRD2; PIAS2; NRBF2; AATF; RUVBL1; LOXL2; ZBTB18; MEF2A; ELK1; NCOR2; MAFB; BRF2; MYBL2; EGR3; AFF4; VGLL4; MAFG; RBM14; SMAD1; BMI1; KLF12; NONO; HLTF; AEBP1; UIMC1; VEZF1; CTR9; PMF1; RUVBL2; HCFC2; NR2E1; TAF1D; STAT5A; FOSL1; DDX5; TSC22D2; CHD7; HSF2; C1D; FOXD1; USP22; NR1I2; CREB3L1; ZNF226; SMAD2; NAB1; NFKBIB; BRPF1; MITF; GLI3; ARNTL; TADA3; CREBZF; PTTG1; BAZ1A; TP53; RUNX1; BTAF1; ZNF267; CREB3; NRIP1; TAF4; THAP1; PURA; MTF2; MLX; SUV39H1; HEY1; ADRB2; FOXO1; CITED1; TRAK1; AIP; ZNF473; MAZ; TBP; MBD2; SCAND1; GATAD2A; ELF1; FOSB; SIX1; UBE2I; ZNF23; BRD4; ZNF189; PRKDC; MAFF; PQBP1; EED; SAP18; EP400; PPARG; LPIN2; RFX5; TFCP2L1; HNRNPD; MTF1; MED6; NFE2L1; KAT7; MNT; RXRA; ERCC2; BRCA1; GABPB1; BCL11B; IL16; SSRP1; SMARCE1; RBBP8; NCOA6; DDIT3; HTATIP2; ZNF24; PSMC3IP; LEF1; ORC2; RUNX3; TWIST1; NFATC1; NCOA4; SOX4; GATA4; RNF141; RFX7; ZNF131; ZNF432; MYCBP; RBBP7; PITX1; TAF9; HMGN3; USF2; TSG101; ERG; KLF7; TSC22D3; TBPL1; TCFL5; ING3; YWHAB; SOX9; ATF1; MTA1; RNF14; UBE3A; DNAJC1; HOXC6; HDAC9; BCOR; SOX15; MSX1; TOX; HOXC10; ETV5; RBM39; SUB1; FOXO3; ASCL1; EDF1; ZNF266; SERTAD2; EMX2; TLE4; KDM5D; IKBKAP; RHOA; NKX3-1; PDLIM1; ZMYM2; SMAD3; CRK; TLE1; ID3; ARID4B
Down-regulation	147	GRHL2; RAD21; MYCL; JUN; ZNF611; ZNF512B; NFE2L2; BCL11A; KAT2B; REL; FOXF2; ZNF623; HIVEP1; AHR; ZNF264; MNDA; NFKB2; CDK2; ZNF571; ZNF22; ARNTL2; MED21; ZNF43; HOXD13; TEAD3; TLE2; ZNF586; SUMO1; TFAP2A; CAMTA1; PIAS4; ZNF124; ZNF74; SMAD6; TRPS1; ZNF331; ARNT2; DLX4; ZNF136; ZNF682; NKX2-1; ZFHX3; IRF6; ZNF350; YEATS2; ZNF667; NFAT5; ZNF652; HOXB13; ZNF33B; MEOX2; ZNF112; DLX5; ZNF430; SOHLH2; TCF7L1; ZNF345; NEUROD1; CREB3L2; ARID5B; OSR2; ZNF665; MYBL1; WWP1; HDAC7; OVOL2; ZNF239; ZNF180; ZNF160; ZFPM2; RBFOX2; GATA6; ZNF117; ZZZ3; PRDM1; JAK2; NFE2L3; THAP4; FOXF1; SMARCA1; HIRA; TCF15; VGLL1; ZNF253; CALR; HOXB2; ERBB4; HSF1; NKX2-2; ID4; CTNNB1; ELF5; NCOR1; FOXC1; SP3; HOXD1; THAP10; PAWR; MEIS2; ZXDC; ZNF551; NR4A2; EN1; ABT1; PHIP; ZNF467; ZNF44; RXRG; ZNF93; TERF1; CREM; HOXB5; ID1; TBX3; WT1; ZSCAN31; HIPK1; MYCN; PBX3; TCF21; HIC2; MEIS1; TGIF1; HOXD3; ZSCAN18; INSM1; NANOG; JUP; NR4A3; AR; PAX6; REPIN1; CREB1; NR2F2; TFAP2C; THAP11; NR2F1; EYA1; TBX2; ZFP36L2; PHF20; DAXX; MECOM; RORA; SATB1; DACH1; ID2