Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76921	Vx-745	GSE92742	MCF10A	Human	6h	2uM	EID0441

Response Information :

Types	Number	Response transcription factors
Up-regulation	125	SMARCD2; ZNF586; ZNF587; ZNF134; ASH2L; ZNF211; ZNF264; STAT2; ZNF394; RBM14; MAX; ZNF446; NFKB1; TRIP6; MITF; PAX8; ADNP2; PMF1; NPAS2; NFRKB; ZNF764; BHLHE41; SATB2; ZNF419; TRIM29; MAFF; KAT7; RNF141; NFYC; ZMYND8; TOX3; ZNF606; AIP; KAT5; CNOT6; TCEA1; HIRA; HOXA5; SMAD5; FOXG1; PURA; KLF5; ZNF304; BAZ2B; CHD3; MTA1; PATZ1; ZKSCAN1; MYCL; HMGXB4; IKZF5; HOXB2; TRIM16; TFCP2L1; SALL1; ZNF467; MXI1; YAP1; HLF; MNDA; VEZF1; PHF2; ZBTB11; RNF138; CREB5; MAF; ZNF24; ATF3; ETV4; TOB1; TCF21; CUX1; RBBP4; ZNF544; NAB1; ELF3; ZBED1; FOXE1; ATF4; ZNF91; LITAF; DNMT3B; DDX17; TCFL5; AFF1; E2F2; YWHAB; RNF14; CITED1; ZNF443; KDM5D; ZNF274; CEBPD; SAP18; NR4A3; TBL1X; IRF7; SOX4; NR3C2; MAFB; SMARCA1; HES1; LEF1; SATB1; PBX2; AES; ZNF131; KLF6; BIRC2; PIR; MEIS2; NR1H2; ZNF331; EYA1; KAT6B; FOXF1; EGR3; IRX5; FOS; SOX9; TCF4; TLE4; NR4A2; ID3; ARID4B
Down-regulation	77	BTG1; TCF7L1; YEATS2; ACTL6B; TBL1XR1; HIF1A; LOXL2; BRIP1; SMARCA4; RAD21; ZNF22; LMCD1; TAF1A; TTF2; ZFHX3; YBX1; PNRC1; SOX3; ZEB2; ACTL6A; AATF; KAT2B; TRIB3; HOXB6; RB1; NR5A2; CBFA2T3; SOX10; BASP1; MYBL1; ATN1; SPIB; UBP1; CCNE1; MYT1; ST18; CTNNB1; NEUROD1; CHD9; ENO1; ZNF721; CALR; ZIC1; ARID1A; CTBP2; TERF1; BCOR; OSR2; ETS1; DEK; POU2AF1; NFATC3; KLF4; HOXD1; THAP11; MED24; PHIP; PSIP1; FOSB; PAX5; KLF9; TCF7L2; MYCN; TFAP2C; ZFP36L2; RUNX1; SHOX2; TRPS1; RFX5; DMTF1; ASCL1; ID1; ABL1; ZEB1; NR2F1; TLE1; ESR1