Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76920	Vx-745	GSE92742	MCF10A	Human	6h	10uM	EID0441

Response Information :

Types	Number	Response transcription factors
Up-regulation	191	ETV1; ASH2L; PHF8; TAF10; PCBD1; PIAS2; HDAC9; NCOR2; TCERG1; DDX5; NRBF2; BMI1; AATF; SMAD1; FOXG1; MNAT1; KLF12; MYBL2; MED1; ZNF528; ELF1; ZNF672; FOXD1; ZNF143; NUP62; NR2E1; PCGF2; TAF4; AFF4; TADA2A; MAZ; LZTS1; EGR1; TRRAP; ELK1; MBD2; AEBP1; MLX; HCFC2; KDM5D; HDAC6; PMF1; NFKBIB; BRF2; HOXA5; TAF1D; USP22; ZNF473; RUVBL2; KAT7; TOB1; UIMC1; CITED1; RBM14; ATF5; SP2; MEF2A; BATF3; RBPMS; ZNF576; RFX7; TBP; TP53; FOSL1; YAF2; CREB3L1; SUV39H1; CTR9; BAZ1A; CRY1; BRD8; BLM; TMF1; BAZ2B; SMAD5; TTF2; ZNF23; NR1I2; ERBB2; YEATS4; RXRA; LHX2; HSF2; MTDH; PRKDC; TSC22D2; EED; SAP18; SATB2; ZMIZ2; MAFB; PPARGC1A; MAGED1; ARNTL; RERE; RNF6; HOXC6; GLI3; RFX5; CBFB; UBE2I; NFE2L1; MYCBP; C1D; NCOA6; ADNP; PHF2; BCL10; DDIT3; PSMC3IP; SCAND1; ZNF432; MSX1; GABPB1; HNRNPD; ZNF267; LOXL2; RBBP7; CREBZF; RCOR3; NFYC; RNF141; ZFP64; SMAD2; ZBTB18; HLTF; ASCL1; SPIB; SIX1; ZNF226; ZNF384; AIP; NPAS2; BRPF1; VDR; RNF14; EGR3; EGR2; SUB1; SMARCA2; ZMYM2; BCL11B; VEZF1; PTTG1; NR1H2; PATZ1; NEDD8; MED6; SOX15; FOSB; CREB5; HDAC1; MTA1; ZNF83; MLXIP; ETV5; HOXB7; MAFF; SIX2; BRCA1; TSC22D1; HEY1; RUNX1; CBX3; MNT; PIR; FOXO3; ID3; NKX3-1; SOX9; HTATIP2; PAX5; TWIST1; FOXO1; CRK; TFEB; ATF1; TOX; PDLIM1; RHOA; IKBKAP; NFIB; TSC22D3; NR2F2; NRIP1; ARID4B; TLE4; TLE1; SHOX2; THAP11; FOS
Down-regulation	144	REL; NFE2L2; JUN; MNDA; ZNF571; BTG1; ZNF611; RAD21; NFKB2; SMARCA1; ZNF43; ZNF117; SUMO1; OSR2; MYCL; PAWR; HOXD13; LIN28A; ZNF623; ZFPM2; ZNF22; BCL11A; ZNF682; ZNF74; ZNF257; PITX2; TEAD3; AHR; GRHL2; CREB3L2; ZNF160; URI1; ZNF264; ZNF586; TBL1XR1; FOXF2; TRPS1; TFAP2A; TLE2; ZSCAN31; TBX21; CAMTA1; DLX5; ZNF331; RB1; KLF1; IRF6; CREM; CALR; MYBL1; NFAT5; ZZZ3; ZNF239; ZNF124; ZFHX3; ZNF33B; HIVEP1; ZNF85; DEAF1; TCF7L1; ZNF573; ARID5B; DLX4; ZNF136; VGLL1; KAT2B; NKX2-1; ZNF165; HIRA; KLF3; NR4A3; NKX2-2; ZNF180; CDIP1; HOXD1; PHIP; ZNF467; NFE2L3; ID4; TERF1; SMAD6; SOX11; TXNIP; OVOL2; HBP1; GATA6; EPAS1; HOXB2; HHEX; DAXX; NR4A2; MGA; ZNF512B; TGIF1; HOXD3; PRDM2; ELF5; TRIM24; NR5A2; CRYM; JUP; ERBB4; PRDM1; FOXN3; ZIC1; TCF4; NEUROD1; ZNF44; DNMT3B; PAX6; ZNF148; KLF11; HSF1; ZNF423; TBX3; ZXDC; CCNH; HIC2; AR; KLF9; EN1; ELF3; WT1; SPDEF; ID1; MEIS2; TBX2; IRF7; CERS6; ZNF91; ZBTB16; BHLHE41; MECOM; NR1D2; DACH1; HMGA2; ESR1; IRF9; NFATC3; FOXF1; RORA; PHF20; NR2F1; SATB1