Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76915	Tgx-221	GSE92742	MCF10A	Human	6h	0.08uM	EID0441

Response Information :

Types	Number	Response transcription factors
Up-regulation	123	AFF4; ASH2L; TAF10; CTR9; MDM4; PCBD1; BAZ2A; AEBP1; RBM14; TCERG1; TOB1; RFX7; FOXN2; NR2E1; HMG20A; PHF8; ZBTB24; ARNTL; CCNT1; ZNF274; MAZ; SMAD5; NUP62; ATF5; TRRAP; ETV1; ZBED4; ZBTB25; PPRC1; GATAD2A; SPEN; TLX3; PRKDC; ZNF672; HDAC6; CITED1; NCOR2; HDAC9; MED1; SMAD1; HEY1; AIP; NFE2L1; RELA; PCGF1; USP22; ADRB2; DDX5; BRD4; TFCP2L1; MBD2; UBE2I; MAGED1; PIAS2; NLK; FOXG1; ZFP36L2; BRD8; MTDH; TFCP2; ZNF23; RUVBL2; BAZ1A; ZKSCAN1; MED24; BCL10; ZNF337; STAT6; DPF2; TFAM; RB1; KLF7; SSRP1; KMT2B; FOSL1; BRPF1; ATF7IP; NR1I2; TBP; RNF138; SUV39H1; EED; PTRF; GATA4; FOXD1; GTF2I; ZBTB18; NPAS2; SOX15; CNBP; FOXO1; KDM5D; RUNX1; BRF2; BMI1; IKBKAP; KLF13; NR2F2; MKL2; TSC22D1; SERTAD2; YAP1; SIX1; BIRC2; TBPL1; RBPMS; FOXO3; KAT6B; SOX9; PDLIM1; FOS; HOXC6; HMGA1; NKX3-1; EMX2; KLF10; ID1; CRK; ARID4B; ASCL1; ID3; TLE1; THAP11
Down-regulation	114	JUN; ZNF611; NKX2-2; GRHL2; ZNF586; KAT2B; NFKB2; MNDA; TLE2; NFE2L2; ZNF512B; TOX3; HHEX; REL; ZSCAN31; ZNF571; EVX1; TULP4; LIN28A; ZNF112; FOXF2; TCF25; GLI1; SMARCA1; ZNF160; CREM; ZNF239; IKZF1; ZNF93; TEAD3; SOHLH2; NEUROD1; MAK; AHR; HOXB2; E2F8; ZFPM2; ZNF43; MYCL; PCGF3; SALL1; BACH1; RBFOX2; GATA6; LOXL2; PEG3; ZNF665; WWP1; ZNF652; ZNF331; CREBL2; PBX1; PHIP; ZNF423; TFAP2A; NR4A2; ZNF91; ZNF232; BCL3; NFE2L3; OSR2; ZBTB38; FOXF1; SMARCD3; HLF; NR4A3; PFDN5; TFAP2C; ARID5B; ERBB4; TRPS1; FOXJ1; DEK; ZBTB20; NFAT5; NR1D2; HOXB5; MAF; NR3C2; MYBL1; NR0B1; HLX; FOSL2; NANOG; BHLHE41; ELK4; FOXE1; CTNNB1; MEIS1; MEIS2; SMAD6; ZNF117; TBX3; KLF2; ZIC1; IRF6; NFATC3; TGIF1; EDF1; RORA; ID4; POU2AF1; HIRA; PAX6; TBX2; ATF3; SATB1; NR2F1; ZHX2; MECOM; DMTF1; ID2; ESR1; DAXX