Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76912	Tgx-221	GSE92742	MCF10A	Human	6h	10uM	EID0441

Response Information :

Types	Number	Response transcription factors
Up-regulation	132	PHF8; PCBD1; SMAD1; ASH2L; SALL2; MAGED1; TRRAP; ETV1; ZBTB18; ZNF771; MLXIPL; TCERG1; HOXA4; MED1; RERE; VPS72; ATF5; HCFC2; SREBF1; TRIP6; HDAC9; CHD8; TAF4; TSC22D4; PRKDC; TAF10; HDAC6; USP22; NUP62; MAZ; ZNF222; FOXO4; PMF1; MED15; GLI3; TMF1; SMARCD2; MTA1; RBPMS; BRF2; LZTS1; NRBF2; NCOR2; TFAM; ZNF274; KLF7; PPARGC1A; RBM14; RYBP; NR2E1; HOXA5; HMGB3; ELK1; MTDH; SPEN; DDX5; ADRB2; CITED1; HEY1; DDIT3; NLK; CTR9; SAFB2; BAZ2A; BAZ1B; PIAS2; SUV39H1; BRD2; BAZ1A; BPTF; KAT6A; HIPK2; FOXD1; SSRP1; KMT2B; SAP30; FOSL1; BAZ2B; TBP; MED24; SMAD5; BRD4; ZNF267; GATAD2A; PATZ1; SCAND1; VDR; CBX6; KAT2A; FOXO1; CREB5; CBFB; BRD8; BBX; ZNF24; TWIST1; KDM5D; MED13; PTTG1; SMAD3; ZNF432; IRF8; HSF2; MNT; NFIB; ING3; RRN3; ASCL1; SAP18; IKBKAP; EGR2; PSIP1; TBPL1; NKX3-1; AEBP1; MAFB; FHL2; RBBP7; SIX1; EGR3; STAT6; TSC22D3; CRK; TFEB; ID3; EMX2; NRIP1; ARID4B; FOXO3; TLE4; ISL1; FOS
Down-regulation	110	PGR; OSR2; NFE2L2; NFKB2; ZNF623; SOHLH2; RREB1; ZNF239; TLE2; REL; GRHL2; NCOA1; ZSCAN31; TFAP2C; FOXF2; ELF5; PSMC3; TEAD3; SOX11; CREM; KLF1; MNDA; BCL11A; HMGB2; NEUROD1; DLX4; JUN; TOX3; CAMTA1; NKX2-1; FOXC1; ZNF573; DLX5; TRPS1; BACH1; ZNF512B; PRDM2; TFAP2A; TAF12; PCGF3; ZNF33B; PHIP; ZNF586; TDP2; ZNF331; MYBL1; NKX2-2; GATA6; ZNF117; DAXX; AES; URI1; LIN28A; PEG3; TFDP2; ZNF124; EN1; ZFPM2; PAX6; ESR1; HHEX; FOXL2; ARID5B; PFDN5; HOXD3; SIAH2; EPAS1; TCEB2; IRF6; ZNF43; CREB3L2; GTF2I; E2F2; KLF4; TBL1X; SMARCA1; NFE2L3; TGIF1; IRF1; HOXC10; NR4A2; FOXN3; ZNF652; LMCD1; ELF3; DACH1; FOXF1; TBX2; TXNIP; ID1; DMTF1; HMGA2; MEIS1; NR2F1; WT1; KLF10; ZNF423; ZIC1; SPDEF; TCF4; ERBB4; ZHX2; TBX3; MECOM; ABL1; PHF20; ID4; LEF1; ZEB1; SATB1