Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76905	Pyrazolanthrone	GSE92742	MCF10A	Human	6h	2uM	EID0441

Response Information :

Types	Number	Response transcription factors
Up-regulation	196	ASH2L; PHF8; TFE3; JARID2; PRKDC; PAX8; MAF; ZNF587; ZBTB7A; HMG20A; TFEC; ZNF672; EP400; TBL1XR1; NRBF2; MDM4; TGS1; DDX5; MSC; GATAD2A; ELK1; PCGF2; PURA; MLX; NOCT; KAT7; ETV1; MAGED1; CSDE1; L3MBTL1; MNAT1; CITED1; NUP62; ARID4A; TRRAP; BRD7; BTG1; ZEB2; TCERG1; PCBD1; RBM14; MLXIPL; RCOR3; SETD3; RBBP4; AFF4; CHD9; MTA2; CUX1; RCOR1; IL16; DDIT3; BRF2; NAB1; MITF; SATB2; AATF; FLNA; GLI3; MAX; TP53; SNW1; HMBOX1; MAFG; SREBF1; SF1; MSX1; CNOT1; TSC22D2; TOX3; BRD4; RBPMS; SMAD1; ZNF654; ZNF267; BAZ2A; CBFB; ADNP; ARID3B; ZNF143; SMAD5; LZTS1; NCOA1; TAF1; NPAS2; SSX1; NFX1; FUBP1; PPARG; ZNF160; HMGB3; ADRB2; ZNF783; HDAC1; POLR2A; DNAJC1; TDP2; ZNF274; SAFB2; CUX2; ZNF189; ZNF516; KDM5D; E2F3; TFAP2C; ENO1; NR1I2; TXNIP; ZNF282; MED4; RYBP; MED1; USP22; HDAC6; BRD2; EZH1; HSBP1; RERE; TRIP6; SOX13; THRAP3; KDM2A; DDX17; GTF2IRD1; SP2; EGR2; NFKB1; TWIST1; RBBP5; NFYC; GABPB1; TBP; ELF4; SMARCA2; HDAC4; IKBKAP; BRPF1; HEY2; SNAI2; ZNF281; LPIN2; SAP18; ZNF91; MYCBP; JUP; NFATC3; ZNF721; FOSL2; MNT; FOSL1; AFF1; SERTAD2; KLF6; NR1D2; FOXO1; SIX2; CREB5; ZNF131; HSF2; FOSB; MKL2; HTATIP2; HOXC6; TCFL5; SIAH2; NFAT5; ID2; RBL2; SIM2; CRK; MED24; MEOX1; SIX1; TBPL1; MLXIP; CENPF; ATF1; FHL2; PIR; NFIL3; ABL1; KLF10; LMCD1; EMX2; RFX5; RHOA; FOXO3; ERG; EYA1; ATF3; EGR3; TBX3; CREB1; THAP11; ARID4B; FOS
Down-regulation	170	YBX3; PAWR; RUVBL2; INSR; ZNF573; ZNF264; CAMTA1; THAP10; FOXG1; ARID5A; PSMC3; ZNF580; USP21; ARNTL2; TOB1; REL; ELK3; CARHSP1; AHR; MEOX2; PFDN5; SP140L; POU2AF1; BCL11A; NFATC1; ATN1; TGIF1; GATA6; MAK; THAP7; ZSCAN31; ZBTB17; ST18; ZNF239; RFC1; ZNF423; ZNF165; ZFPM2; SUPT3H; ZBTB18; IRF3; KAT2B; XRCC6; VGLL1; GRHL2; FOXK2; ZNF74; ZFP69B; NR2C1; ZNF571; DEAF1; ZZZ3; SRCAP; PQBP1; KDM4C; CTBP2; ARID5B; ZNF835; SREBF2; DLX2; E2F8; NFE2L2; MXD3; TCEB2; TOX; HOXA5; ZMIZ1; NFE2L3; NFKB2; TAF10; TRIM28; FOXC1; CREM; EHF; ZNF112; ZBED2; SOX11; ID1; HIRA; HHEX; GCFC2; TLE2; CXXC1; SIX6; PRDM2; ERF; HES1; NOC2L; PNRC1; LZTR1; EN1; ZNF33B; ZNF551; KLF2; ZIC1; ERBB4; FOXJ1; CRY1; ZNF45; MEIS1; PHF20; HMGA2; SCAND1; BACH2; YBX1; MED17; MYT1L; GTF3A; IRF7; CBFA2T3; ZNF593; ZNF415; ZNF536; ASXL1; NKX2-1; NR4A1; RREB1; HMGN3; MEIS2; WWTR1; ZNF107; ATF4; HMGB1; WNT4; ZNF468; CBX4; OLIG2; RING1; PRRX1; ZNF467; ZBTB38; CCNC; PAX6; TEAD4; ZEB1; PHF1; ETV5; DAXX; MXI1; CEBPD; IRF6; TP63; PAX5; BASP1; AES; MXD4; TCF4; ZFP36L2; NFIB; MYBL1; PHIP; ZSCAN18; HOXD1; MNDA; PSIP1; NR2F1; OSR2; BIRC2; CBX7; TLE1; SHOX2; MECOM; SMAD3; ELF3; ERBB2; ID3; RORA; SATB1; KAT6B; NR4A2