Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76891	Ruxolitinib	GSE92742	MCF10A	Human	6h	0.4uM	EID0441

Response Information :

Types	Number	Response transcription factors
Up-regulation	113	ASH2L; TAF10; PCBD1; TCERG1; NUP62; AATF; JARID2; BRD2; PRKDC; TRRAP; TTF2; ZNF143; HDAC6; PMF1; CRY1; PHF8; HCFC2; ZBTB7A; NFE2L1; RBM14; MTA2; EP400; MLX; GLI3; RERE; GATAD2A; CSDE1; CUX1; MTDH; ETV1; CTR9; NR2E1; BAZ1A; BRD4; ZBTB18; SPEN; MITF; UBE2I; PIAS2; PCGF2; UIMC1; NCOR2; NPAS2; FOSL1; ZNF432; MSX1; HOXA5; YAF2; HSF2; THRAP3; BAZ2B; SMAD5; RUVBL2; STAT1; GFI1; TBP; MED1; USP22; HDAC9; EMX2; PHF2; ZBTB11; RFX7; HEY1; PTTG1; BRPF1; MAGED1; HNRNPD; CENPF; MAFB; SUV39H1; PTRF; POLR3F; NEDD8; ZNF384; LITAF; FOXO1; HOXC6; SIX1; CREBZF; ZMIZ1; MYRF; CREB5; TCFL5; BMI1; MED24; FOXO3; BIRC2; CDK9; SMAD1; BRF2; IKBKAP; EGR3; ANKRD1; NCOA3; TSC22D2; ZNF410; CREG1; CITED1; TBPL1; FOSB; ZHX2; FOS; AEBP1; PIR; ATF1; NR2F2; CRK; RHOA; ARID4B; SOX9; SMAD3; TLE1
Down-regulation	115	RAD21; ZNF264; NKX2-1; MYCL; ZNF611; SOHLH2; REL; NFE2L2; NFKB2; MAF; NR1H3; ZNF136; TRPS1; OVOL2; ZNF623; CEBPD; TLE2; ZNF160; ZNF571; KAT2B; TULP4; ZNF124; ZNF512B; SMAD6; BCL11A; ZNF665; NCOA1; TOX3; DLX4; ST18; ZNF573; ZSCAN31; AES; ZNF430; GRHL2; FOXF2; ELF3; CREBL2; TFDP2; CREM; JUP; ZNF721; DLX2; ZNF711; NEUROD1; SMARCA1; RB1; ZNF253; ZNF586; SUPT3H; PHIP; ZFPM2; ZNF43; IRF6; PFDN5; MYBL1; ARID5B; OSR2; CBX4; DACH1; ZNF652; URI1; ZNF329; TGIF1; ERBB4; ZNF44; ZNF536; PCGF3; DLX5; ZNF117; BHLHE41; PEG3; ZNF331; BASP1; CALR; ZNF248; NR1D2; NKX2-2; ZIC1; LIN28A; TXNIP; SATB2; MNDA; ZBTB20; FOXF1; ZNF217; CTNNB1; NANOG; TCF4; MECOM; EN1; KLF11; TCF7; PAX6; CD3D; NR2F1; KLF9; TOX; NFE2L3; GATA6; HHEX; ID4; NR4A2; HIC2; TBX2; ID1; CREB1; MEIS2; PHF20; MEIS1; KAT6B; ID2; TBX3; GATA3; DAXX