Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76889	Ruxolitinib	GSE92742	MCF10A	Human	6h	10uM	EID0441

Response Information :

Types	Number	Response transcription factors
Up-regulation	145	BTG1; GATA2; DLX2; SFMBT1; MYB; SMARCD1; ZBTB48; ZKSCAN3; BRD2; TERF2; ATF4; MGA; AEBP1; RAD21; GFI1; MED12; DEAF1; LZTS1; ZNF134; ZNF669; ELF1; DLX4; ELF4; TCF12; NKRF; ZNF394; GLI1; GMEB1; GTF2I; ZNF430; HMG20A; POU4F1; KAT7; CNBP; MSX1; AFF1; NHLH1; TGIF2; TFDP2; NFKB1; ZNF580; HOXD11; PBX3; CTCF; ZNF606; CHD7; CBX2; HOXC4; ZNF24; YAP1; ETS2; ZSCAN32; ARNT; EHMT1; HOXC10; FOXA1; BCOR; RNF111; NPAS2; GLI3; EGR1; MEF2A; RELA; NFYC; BCL10; PKNOX2; ZNF510; RNF138; RING1; DLX5; TCF3; MBD2; TGFB1; RREB1; LPIN2; MAZ; CDK9; ELF3; DR1; ZFP64; MDM2; AR; ZBED1; SIX2; SMAD5; ARRB1; BLM; LEF1; DBP; UBTF; E2F2; MTF2; ERBB2; RFX5; TRIM25; NFATC4; SOX4; CHD4; SMARCA1; CITED1; IRF4; BCL11A; ZNF43; HMGA1; HHEX; BACH2; SMAD3; ZNF266; TRIM27; HNRNPD; ID2; SATB1; ZNF148; NFYA; SOX10; E2F5; JUNB; CREB3L2; ARID5B; HIPK1; HOXA1; ZNF117; RNF6; HDAC1; XBP1; PIR; PAX6; BIRC2; SMAD1; ESR1; HOXB7; NFATC3; ZHX2; ID3; HMGA2; ZNF131; TGIF1; HOXB2; TLE1; NCOA2; DAXX; HES1; NFKB2; CRK; THAP11
Down-regulation	105	PSMD9; TOB1; BCL6; ZNF212; ELF5; NFYB; BLZF1; BASP1; TFEC; MED21; NR2C1; CARF; MAFG; CDC5L; MTF1; BAZ2B; ZBTB38; PAWR; ZNF268; ZHX3; SND1; ADRB2; TBL1XR1; IRF8; ZNF205; TRIM29; HSBP1; PSMC3; PMS1; SAFB2; EVX1; KAT6A; BHLHE41; INSR; HIPK2; ESRRG; HMGB3; EMX2; ZNF281; DNAJC2; GRHL2; MED23; MLXIPL; BPTF; PTRF; TP53; MAFB; COPS5; HSF2; PITX1; PRDM10; NCOR2; NCOA4; TMF1; POLR3F; MNDA; THAP10; ZNF721; RBPMS; ZNF83; SNAI2; HTATIP2; NANOG; ST18; ANKRD1; CEBPD; TSC22D3; ZMYND11; CREB5; CCDC59; RSF1; DNAJC1; MYRF; EHF; LIN28A; PEG3; PSIP1; ZNF532; CTBP2; RBM39; MLXIP; NR4A1; TCF7L2; NFIB; ARID4B; IKBKAP; SPDEF; KAT6B; MYCN; IRF9; NFIL3; TSC22D1; HIRA; ABL1; WT1; NR1H2; MECOM; TBX3; TRPS1; ASCL1; HOXA10; ZEB1; ID1; FOS; TCFL5