Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76886	Pelitinib	GSE92742	MCF10A	Human	6h	2uM	EID0441

Response Information :

Types	Number	Response transcription factors
Up-regulation	129	BRD2; DDIT3; TRIM22; RERE; VPS72; CITED1; ZBTB48; TSC22D3; MEN1; TRRAP; RCOR1; BRD8; ELF5; ARID1A; DPF2; E2F8; MDM4; WHSC1; RBBP8; NFE2L1; SAFB; MAGED1; MYB; ASH2L; JARID2; PHF8; BRD4; KAT5; TAF4; HLTF; INSR; MYCL; SALL2; ZNF337; BHLHE41; EHF; NONO; HDAC6; EZH1; TFCP2; PBX1; SIN3B; HAND1; LZTS1; BAZ2A; FOXJ3; RXRA; ZNF516; NR2E1; HDAC9; CEBPG; BRF2; AATF; EYA2; SETDB1; RBPMS; SOX13; ZNF384; CUX2; POLR2A; MED20; ST18; BAZ2B; PIR; TCF25; ZNF195; SSRP1; FOXA1; AEBP1; ATF4; HDAC5; PTTG1; PRKDC; THRAP3; TOX; TDRD3; NR5A2; CHD4; TCEA1; HMGB1; SMAD1; ZKSCAN1; DMTF1; SSX1; TGFB1I1; AIP; KAT2A; ZNF24; SPEN; NAB1; TFAP2C; ETV5; ZMIZ1; SAP18; CTR9; SOX17; CENPF; SMARCA1; TRIM24; TRAK1; HOXD1; HMGB3; LOXL2; MYCN; PCGF3; MYRF; ZNF532; SUB1; NCOA2; NFIL3; ZBTB18; PSIP1; NFIB; ATF3; NR1H2; ASCL1; IRF9; TCF7L2; CREB1; ELF3; CEBPA; SIX1; ARID4B; EMX2; KDM5D; MECOM; FOS; TCEA2; CITED2
Down-regulation	108	PSMD9; MYC; AHR; REL; ZNF573; NFKB1; CARM1; ZEB2; ELK3; PA2G4; HOXA7; ZBTB38; MEOX2; SMAD7; CEBPZ; BCL10; PNRC1; ZNF611; E2F4; ETS2; KLF1; SSBP2; LEF1; PBX3; CHD1; CBFB; KLF11; RAN; KLF2; YWHAB; BACH1; ZNF430; ZNF468; CHD9; CREM; ZNF264; ZNF160; SIAH2; HDGF; POU2AF1; MTF1; CASZ1; PEG3; ENO1; FHL2; CBX3; ZNF652; TGIF1; NR4A3; THAP4; ELF1; NFAT5; WWP1; DEK; FOSL1; PAX6; IRF2; PAX5; RXRG; ZNF721; RNF10; NFKB2; CNBP; ZNF44; MAFB; WWTR1; TCF7; INSM1; FOXD1; ZNF107; DAXX; KLF4; LITAF; ZNF91; AES; ARID5B; SIX2; HMGA2; MYBL1; ZFP36L2; NR4A2; TSC22D2; ZNF200; TRPS1; STAT4; TXNIP; KLF9; PLAGL1; YAP1; TLE1; IKBKAP; ERBB2; BIRC2; IRX5; NR1D2; HOXB2; KAT6B; TBX2; ZNF131; ZNF331; HOXA10; KLF10; HOXC6; EGR3; ZEB1; TCFL5; THAP11; SATB1