Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76873	Pf-431396	GSE92742	MCF10A	Human	6h	10uM	EID0441

Response Information :

Types	Number	Response transcription factors
Up-regulation	132	HOXA4; PCBD1; TSC22D3; NFE2L1; ASH2L; AFF4; HCFC2; PEX2; HOXA5; SMAD5; VPS72; GFI1; HEY1; BTG1; RYBP; THAP1; MAZ; FOXN2; PMF1; KLF7; GLI3; AEBP1; SUB1; TSC22D4; MNAT1; RFX7; ELF4; MITF; ELF1; NRIP1; C1D; TTF2; HAND1; HDAC9; RARA; PHF8; POU3F2; EGR1; ZBED4; GTF2A1; NCOR2; NR2E1; ADNP2; YEATS4; PIAS2; BRD4; LDB1; ERBB2; ZBTB18; ACTL6A; MLX; SAP30; ZNF669; DNMT1; NR1I2; IKZF5; BMI1; SP100; RLF; SP2; TAF10; FOSB; SPEN; ID3; MED1; ZNF552; USP22; RARB; PHOX2B; YAF2; SMARCE1; TFAM; PPARGC1A; HOXB6; EED; GATAD2A; HDAC6; SMAD1; HMGB1; PRKDC; GABPB1; ZFP36L2; ZNF140; HOXA1; NFKBIA; MXI1; KMT2B; PBX3; CITED1; MSX1; SUPT4H1; MYCBP; ASCL1; NFATC3; UBE3A; ZNF84; JUNB; KLF13; ZNF432; MLXIP; CUX2; HSF2; PTTG1; SAP18; ZNF532; BRF2; EGR2; ZNF12; TBP; MYCN; SOX15; MAGED1; TLE4; PIR; TXNIP; KAT6B; SERTAD2; MAFB; RHOA; KLF6; PDLIM1; MYRF; ATF3; KLF10; HTATIP2; SNAI2; NFIB; EMX2; TLE1; CITED2; FOS; THAP11
Down-regulation	119	ZNF611; ZNF160; MYC; TBL1X; ZNF721; PIAS4; ZNF571; ZNF665; ZNF573; ZBTB38; NFKB2; BCL11A; LIN28A; TLE2; RREB1; REL; SCAI; SMARCA1; ZNF623; ZNF512B; CDYL; MYCL; SNAPC4; ZNF264; PITX1; ZNF239; BRD3; PEG3; DEAF1; FOXF2; PLAG1; RUNX3; ADRB2; CREBL2; EYA2; GCFC2; MAF; FOXA1; CREM; TEAD3; PURA; NANOG; TRIM32; NKX2-2; PHIP; NFE2L2; PQBP1; IRF2; TFAP2C; PCGF3; E2F5; MAK; TRPS1; TRIM16; NR1H3; GTF2F1; ZNF331; TRIM27; DLX4; ZNF415; HHEX; MNDA; NFE2L3; PITX2; TCF25; ERCC3; AHR; STAT4; SMARCA4; NKX2-1; PHF20; NR0B1; GRHL2; TERF1; CBX7; TDP2; MYBL1; PREB; INSR; ZNF43; EHF; NR4A2; CBX4; HMGA2; ZSCAN18; ZNF91; ZNF44; ZNF93; XBP1; ZBTB20; HLF; NEUROD1; ELF3; RBPJ; CTNNB1; CTBP2; SUZ12; FOXN3; DLX5; IKBKAP; FOXC1; TGIF1; ZNF83; AES; KDM5D; HIRA; CREG1; KLF4; ZNF652; TCF7; NR1D2; ERBB4; TBX2; IRF7; HIC2; CEBPA; SATB1; FOXF1; ID4