Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76863	Ibrutinib	GSE92742	MCF10A	Human	6h	0.4uM	EID0441

Response Information :

Types	Number	Response transcription factors
Up-regulation	82	ASH2L; PRKDC; HCFC2; NFE2L1; ZNF274; HDAC6; ETV1; PCGF2; ZBTB18; TCERG1; ZBTB24; TP53; MLXIPL; PMF1; TAF10; MXI1; TDRD3; PHF8; CRY1; SPEN; MYB; BRD8; CTR9; RLF; ZNF23; HSF2; NUP62; CHD7; TMF1; ZNF84; FOXO1; SP2; KAT6A; MAGED1; HIVEP2; USP22; ACTL6A; LPIN2; TRIM29; MED1; NCOR2; RFX5; BNC2; ZNF140; ANKRD1; ZNF432; ZNF146; ZMYND11; BAZ1A; SUB1; ZNF32; AFF1; PTTG1; CITED1; ZNF83; ZNF226; BRF2; ZBTB11; HMGB1; TBP; MAFB; KLF6; MYCBP; NCOA3; SAP18; TSC22D3; IKBKAP; AEBP1; BCOR; NFIB; ENO1; TAL1; ZNF131; TBPL1; ZNF302; SOX9; RHOA; ASCL1; ARID4B; SHOX2; CRK; TLE1
Down-regulation	80	SOHLH2; REL; NFE2L2; NFKB2; HOXC10; ZFP36L1; FOXF2; DLX5; THAP7; AHR; TLE2; ZNF589; OVOL2; RNF4; CARM1; EP300; DLX2; BCL11A; NR1H3; GRHL2; CREBL2; CALR; MYCL; NKX2-2; FOXF1; PRRX2; MEOX2; MECOM; SMAD6; KAT2B; AES; TOX3; ZNF124; WWTR1; NFAT5; PCGF3; ARID5B; FLNA; NEUROD1; CTNNB1; PEG3; TOX; HIC2; BANP; SMARCD3; TRPS1; CREM; LIN28A; HOXD3; HHEX; NR4A2; TXNIP; SPDEF; HIRA; TBX3; HMGA2; BHLHE41; HOXD1; LEF1; OSR2; PAX6; THAP11; ID1; MEIS1; ERBB4; ELF3; IRF7; SATB1; TCF4; EYA1; KLF5; FOS; PHF20; ZNF331; DAXX; TCFL5; ZNF423; KAT6B; ID4; DACH1