Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76862	Ibrutinib	GSE92742	MCF10A	Human	6h	2uM	EID0441

Response Information :

Types	Number	Response transcription factors
Up-regulation	125	TRIP6; ASH2L; TGS1; NRBF2; PCBD1; PRKDC; MAGED1; HDAC6; MED24; HCFC2; RXRA; HMG20B; JARID2; RFXANK; MLXIPL; PHF8; FOXO1; NFE2L1; TTF2; PMF1; FOXO4; RBPMS; AFF2; TRIM22; RUVBL2; RUNX3; MED4; ZNF222; BPTF; ZNF274; RBM14; KAT6A; NFYC; TMF1; SIM1; ZKSCAN1; BRD8; EED; SP2; ERG; TFEC; AEBP1; CRY1; SREBF1; SP110; ZNF267; ZNF189; LITAF; NUP62; TDRD3; CITED1; PCGF2; HOXA5; MYB; GLI3; BAZ2B; GABPB1; SIX2; ZNF224; ERBB2; ATF7IP; SCAND1; TBP; HSF2; BNC2; BRF2; NR1I2; SALL2; HOXC6; CTR9; CHD7; SAP18; SMARCA2; BMI1; PPP1R13L; NCOA3; USP22; KAT2A; IRF1; ZNF432; TRAK1; SUV39H1; MYRF; MYCBP; ZNF140; PBXIP1; SUB1; SSBP2; KDM5D; BRD4; RSF1; NELFB; SPEN; ANKRD1; CREB5; MED23; ZNF281; RLF; RUNX1; KLF7; ZNF544; HMGB3; HOXB7; AFF1; IKBKAP; ZMYM2; PSIP1; PDLIM1; KLF9; ZEB1; TCFL5; LMCD1; MTA1; NKX3-1; ARID4B; RHOA; TLE1; PBX1; ZMIZ1; NRIP1; CITED2; CRK; PIR; CREB1; TCEA2
Down-regulation	127	DRAP1; ZFP36L1; BCL11A; NFE2L2; NFKB2; SOHLH2; REL; SMARCB1; TOX3; ZFHX3; FOXF2; PMS1; GTF2A2; TBL1X; ZNF239; FOXG1; DLX5; TBX3; DLX2; PURA; CBX6; TULP4; HMGA2; SUMO1; AHR; THAP7; FOXF1; ZZZ3; SATB2; HOXB13; GRHL2; NKX2-2; ZNF573; HSBP1; HIRA; RBBP8; TAF12; HHEX; EP300; CCNH; TLE2; CEBPZ; ZNF623; TRPS1; NFIC; BARX1; ZNF467; URI1; ARID5B; PFDN5; SPI1; RNF138; NR4A1; TFDP2; TGIF1; LOXL2; FLNA; FOXA2; AES; PRDM1; ARL2BP; TGIF2; CREM; ZFP30; NPM1; NEUROD1; XBP1; ERF; LIN28A; HDAC4; SIM2; NKX2-1; CTNNB1; SMARCA1; PEG3; CHD1; YBX1; NR4A2; ZBTB38; CBFA2T3; TGFB1; HIC2; SMAD6; CBX5; ING2; TXNIP; NAB2; RBPJ; LEF1; ZXDC; ID1; ZNF652; MNDA; EPAS1; OSR2; UBE2B; TFAP2C; NFE2L3; ZNF331; NR4A3; MEIS1; ETV5; EYA1; SPDEF; ZFP36L2; ASCL1; ZBTB16; MLXIP; ERBB4; PHIP; THAP11; FOS; HMGA1; DACH1; TBX2; DMTF1; WT1; PHF20; ISL1; EGR3; SOX9; ID4; DAXX; TCF4; SATB1; NR2F1; ZNF423