Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76861	Ibrutinib	GSE92742	MCF10A	Human	6h	10uM	EID0441

Response Information :

Types	Number	Response transcription factors
Up-regulation	107	MAGED1; PLAG1; HMGN3; FOSL2; WNT4; ACTL6B; NFYC; SERTAD2; RCOR1; XRCC6; L3MBTL1; KDM4A; MYT1; SOX11; VGLL1; ZMYND8; FOXK2; TCF20; TDRD3; WWC1; TSC22D3; MZF1; ELF1; PITX2; MXI1; MTA1; LZTS1; POU2AF1; NCOA6; FOXO4; SOX4; BPTF; NFATC1; POU2F1; MED6; AEBP1; GATAD2A; ERBB2; ERBB4; AFF1; MBD2; ZNF711; ZNF589; ZNF232; MYT1L; LPIN2; CCNC; ATF7IP; IL16; BRD4; HLTF; DLX5; NRIP1; GON4L; MTF2; GFI1; NCOR2; HMGB1; PDLIM1; ZNF148; ZNF331; FOXJ3; ZNF248; EGR4; CXXC1; RFX5; SCAND1; SPEN; FOXC1; NFIL3; CREB3L2; RBBP8; NCOA2; BCL11B; ZNF131; CTR9; SIAH2; TBL1X; MYCN; HDGF; GTF3A; EMX2; KLF6; CREB1; HOXC6; RNF6; BHLHE40; DACH1; ZNF117; ZMYM2; PEG3; EYA1; IRF4; NFKB2; IRF9; NFATC3; BIRC2; HOXA10; EGR3; DAXX; NR2F2; PHF20; NFIB; CEBPA; TCEA2; NR4A2; ESR1
Down-regulation	128	DRAP1; MYC; KAT5; CALR; PSMD9; HSBP1; CEBPZ; LITAF; TGFB1I1; TRAF6; POU5F1B; FOSL1; AHR; PA2G4; SSBP2; CAPN15; PPRC1; PBX1; CTBP1; BCL3; TADA3; ZNF22; RNF4; DPF2; NRF1; ZFP36L1; ZNF394; TCERG1; CCDC59; LOXL2; RELA; ZNF593; ETV4; BATF3; VPS72; NR2F6; ZNF669; SMAD7; SAFB2; FOXG1; ABL1; ARNTL; ELK1; PHF2; ATF1; SAP30; LIN28A; FHL2; BMI1; GABPB1; ZNF32; HEY1; TCF21; DEK; SALL1; ELF4; ZEB2; CENPB; CBFB; SMARCA4; RNF138; MEOX2; POLR3F; MNDA; ZBTB43; ZNF160; HDAC4; PITX1; NANOG; ZNF12; ATF5; CD3D; SMAD3; SSRP1; DDIT3; PAX6; STAT4; MAFF; CDK9; WWTR1; ARID4B; CREB5; ZFP36L2; NFAT5; SLC2A4RG; KLF9; ELK3; NKX2-2; HTATIP2; SOX13; SNAI2; TP63; HHEX; ZSCAN18; DNAJC1; MNT; TFEB; SMARCC2; SOX15; FOXF2; TCF7; CREG1; KLF7; NR2F1; ZNF175; ZNF302; FOXF1; HES1; DMTF1; THAP11; ID1; ZBTB16; MYRF; TCFL5; STAT6; IKBKAP; NR1H2; MYBL1; KAT6B; PSIP1; TLE1; GATA3; TSC22D1; KDM5D; ASCL1; MECOM; SATB1; FOS