Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76860	Linsitinib	GSE92742	MCF10A	Human	6h	0.08uM	EID0441

Response Information :

Types	Number	Response transcription factors
Up-regulation	125	ADRB2; VGLL4; RUNX3; ZKSCAN1; BCL3; MYB; FOXK2; ZBTB18; CUX2; GATA6; NFYC; MITF; TRRAP; GTF3A; CITED1; NONO; NFE2L3; SOX4; BASP1; BPTF; TBX1; STAT1; YEATS2; SALL1; ZNF354A; BHLHE40; RELB; MXI1; ZZZ3; CDK8; SOX12; GATAD2A; TGFB1I1; MBD2; RBL1; WNT4; HOXB13; MED24; TRIP11; ARNTL; ZMYND8; NLK; SPEN; SOX13; TEAD3; CNOT6; MEIS2; DDX5; MAFK; TRIM22; NR2F2; ZBED4; SATB2; PNRC1; HBP1; GON4L; PHF1; NPM1; FOXG1; CD3D; GFI1; ZNF23; IRF2; HOXA11; JUND; MAGED1; EYA2; SSBP3; ELF5; ZNF224; OSR2; PIR; BRD4; CHD1; TSC22D3; TBL1X; DMTF1; NAB1; ID2; RBBP5; MED13; SCAND1; HOXC6; MTF2; THAP10; NR2F1; ZMYM2; HIRA; NR1H2; ZBTB38; SATB1; HOXD11; ZFP36L1; PDLIM1; YWHAB; HOXB7; ZHX2; WWC1; ZNF266; RORA; RBBP7; RLF; SIAH2; HOXA10; CBX7; EGR3; ZNF131; ARID5B; AR; NCOA3; MYRF; RBPMS; CITED2; SMARCA1; ESR1; MNT; SPDEF; NFIB; TGIF1; DAXX; NFKB2; THAP11; KAT6B; PHF20; ZEB1
Down-regulation	112	CCNA2; PSMD9; TCERG1; PA2G4; ETS2; RYBP; CREB3; TOB1; CCNE1; ST18; CAMTA1; TFEC; RNF4; RBM14; ATF1; RRN3; AATF; TOPORS; HSBP1; HMBOX1; BAZ2A; DEK; NR0B1; RAD21; PSMC3; TRIP6; PMF1; KMT2A; KAT2A; NR4A1; NEDD8; ASH2L; CDC5L; INSM1; SAFB2; HTATIP2; ZBED2; TBL1XR1; HIPK3; E2F3; BCL11A; CDYL; TXNIP; EED; WHSC1; KLF7; TCF12; PEG3; ZNF263; ZNF415; PURA; DDIT3; CREBZF; ZNF384; ZNF282; LOXL2; SSBP2; NFX1; EDF1; ETS1; RCOR3; REXO4; EZH2; SND1; NUP62; NFATC3; ENO1; BRCA1; ING3; STAT6; CARHSP1; NFE2; NKX2-1; KLF6; KLF10; ZBED1; NR4A3; MEIS1; ID1; SMAD3; JUP; BMI1; RBPJ; ZBTB20; ABL1; HEY1; PBX3; TAL1; TLE1; TLE4; MECOM; CREB1; CCNC; NRIP1; KLF2; HES1; TSC22D2; HLX; BIRC2; KLF5; TBX2; NKX3-1; PBX1; PAX6; GATA3; ATF3; FOS; EMX2; DACH1; TCFL5; ASCL1; ID3